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Single calibration multiplane stereo-PIV: the effect of mitral valve orientation on three-dimensional flow in a left ventricle model

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Abstract

The characterization of flow patterns in the left ventricle may help the development and interpretation of flow-based parameters of cardiac function and (patho-)physiology. Yet, in vivo visualization of highly dynamic three-dimensional flow patterns in an opaque and moving chamber is a challenging task. This has been shown in several recent multidisciplinary studies where in vivo imaging methods are often complemented by in silico solutions, or by in vitro methods. Because of its distinctive features, particle image velocimetry (PIV) has been extensively used to investigate flow dynamics in the cardiovascular field. However, full volumetric PIV data in a dynamically changing geometry such as the left ventricle remain extremely scarce, which justifies the present study. An investigation of the left ventricle flow making use of a customized cardiovascular simulator is presented; a multiplane scanning-stereoscopic PIV setup is used, which allows for the measurement of independent planes across the measurement volume. Due to the accuracy in traversing the illumination and imaging systems, the present setup allows to reconstruct the flow in a 3D volume performing only one single calibration. The effects of the orientation of a prosthetic mitral valve in anatomical and anti-anatomical configurations have been investigated during the diastolic filling time. The measurement is performed in a phase-locked manner; the mean velocity components are presented together with the vorticity and turbulent kinetic energy maps. The reconstructed 3D flow structures downstream the bileaflet mitral valve are shown, which provides additional insight of the highly three-dimensional flow.

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Authors and Affiliations

  1. Institute Biomedical Technology, Ghent University, Ghent, Belgium

    Hicham Saaid, Patrick Segers & Pascal Verdonck

  2. German Aerospace Center, Institute of Aerodynamics and Flow Technology, Göttingen, Germany

    Matteo Novara

  3. Department of Materials, Textiles and Chemical Engineering, Ghent University, Ghent, Belgium

    Tom Claessens

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  1. Hicham Saaid
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  2. Patrick Segers
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  3. Matteo Novara
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  4. Tom Claessens
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  5. Pascal Verdonck
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Correspondence to Hicham Saaid.

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Saaid, H., Segers, P., Novara, M. et al. Single calibration multiplane stereo-PIV: the effect of mitral valve orientation on three-dimensional flow in a left ventricle model. Exp Fluids 59, 49 (2018). https://doi.org/10.1007/s00348-018-2504-5

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  • DOI: https://doi.org/10.1007/s00348-018-2504-5

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