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Expression Profiling of Human Tumors

Diagnostic and Research Applications

  • Book
  • © 2003

Overview

Editors:
  1. Marc Ladanyi

    1. Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. William L. Gerald

    1. Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-x
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  2. Introduction

    1. Front Matter

      Pages 1-1
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    2. Introduction: Present and Potential Impact of Expression Profiling Studies of Human Tumors

      • Marc Ladanyi, William L. Gerald
      Pages 3-7

  3. Technical Aspects

    1. Front Matter

      Pages 9-9
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    2. cDNA Microarrays

      • Paul S. Meltzer
      Pages 11-21

    3. Oligonucleotide Microarrays

      • Marina Chicurel, Dennise Dalma-Weiszhausz
      Pages 23-46

    4. Serial Analysis of Gene Expression (SAGE) in Cancer Research

      • C. Marcelo Aldaz
      Pages 47-60

    5. Tissue Arrays

      • Cyrus V. Hedvat
      Pages 61-72

    6. Microarray Data Analysis

      • Pablo Tamayo, Sridhar Ramaswamy
      Pages 73-101

    7. The Role of Tumor Banking and Related Informatics

      • Stephen J. Qualman, Jay Bowen, Sandra Brewer-Swartz, Mary France
      Pages 103-117

  4. Applications

    1. Front Matter

      Pages 119-119
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    2. Characterization of Gene Expression Patterns for Classification of Breast Carcinomas

      • Irene L. Andrulis, Nalan Gokgoz, Shelley B. Bull
      Pages 121-145

    3. Microarray Analysis of Colorectal Cancer

      • Daniel A. Notterman, Carrie J. Shawber, Wei Liu
      Pages 147-171

    4. Gene Expression Analysis of Prostate Carcinoma

      • William L. Gerald
      Pages 173-197

    5. Classification of Human Lung Carcinomas by mRNA Expression Profiling

      • Arindam Bhattacharjee, Matthew Meyerson
      Pages 199-217

    6. Molecular Profiling of Bladder Cancer Using High-Throughput DNA Microarrays

      • Marta Sánchez-Carbayo, Carlos Cordon-Cardo
      Pages 219-233

    7. Gene Expression Profiling of Renal Cell Carcinoma and its Clinical Implications

      • Masayuki Takahashi, Bin Tean Teh
      Pages 235-255

    8. Expression Profiling of Pancreatic Ductal Adenocarcinoma

      • Christine A. Iacobuzio-Donahue, Ralph H. Hruban
      Pages 257-275

    9. Gene Expression in Ovarian Carcinoma

      • Garret M. Hampton
      Pages 277-294

    10. Classification of Pediatric Tumors Using DNA Microarrays

      • Javed Khan, Marc Ladanyi
      Pages 295-304
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Keywords

About this book

A comprehensive review of the use of global gene expression profiling to understand human tumors. The authors focus on the analysis of human tissue samples for a variety of cancers, including breast, colorectal, lung, renal, ovarian, bone, and brain tumors, among others. A primer on the technology and its novel analytical methods. Contains over 40 color images. Explains both the theory and practice of comprehensive gene expression profiling. Timely and topical, Expression Profiling of Human Tumors: Diagnostic and Research Applications offers every oncologist, pathologists, and cancer surgeons an essential introduction to the most promising new high-throughput investigative approaches in molecular biology-technology that is already dramatically reshaping the future of cancer research, diagnostic pathology, and clinical oncology.

Reviews

"This timely and topical book provides cancer researchers, oncologists, pathologists and cancer surgeons with an essential introduction to the most promising high-throughput investigative approach in molecular biology today...." (biotech-online.com)

"...written clearly and in great detail with excellent often colorful illustrations which make them very easy to follow and very understandable...a major contribution to the field of expression profiling of human tumors for both these in the fields as well as those wanting to learn about this technique and its applications." (Medical Oncology)

Editors and Affiliations

  • Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, USA

    Marc Ladanyi, William L. Gerald

Bibliographic Information

  • Book Title: Expression Profiling of Human Tumors

  • Book Subtitle: Diagnostic and Research Applications

  • Editors: Marc Ladanyi, William L. Gerald

  • DOI: https://doi.org/10.1007/978-1-59259-386-6

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2003

  • Hardcover ISBN: 978-1-58829-122-6Published: 01 May 2003

  • Softcover ISBN: 978-1-61737-375-6Published: 09 December 2010

  • eBook ISBN: 978-1-59259-386-6Published: 01 May 2003

  • Edition Number: 1

  • Number of Pages: X, 399

  • Topics: Pathology

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