Synthesis and biological evaluation of new 2-(6-alkyl-pyrazin-2-yl)-1H-benz[d]imidazoles as potent anti-inflammatory and antioxidant agents Bhookya ShankarPochampally JalapathiKarunakar rao Kudle Original Research 17 April 2017 Pages: 1835 - 1846
Novel derivatives of substituted 6-fluorobenzothiazole diamides: synthesis, antifungal activity and cytotoxicity Marcela PejchalováRadim HavelekVladimír Pejchal Original Research 17 April 2017 Pages: 1847 - 1862
A novel PTP1b inhibitor vanadium-flavone complex: synthesis and pharmacodynamic evaluation in streptozotocin-induced diabetic mice Liying DuanJunwei YeGuiling Ning Original Research 19 April 2017 Pages: 1863 - 1870
Synthesis and biological evaluation of α-methyl-chalcone for anti-cervical cancer activity Bing-zhao RenMourboul AbliseZheng Yang Original Research 22 April 2017 Pages: 1871 - 1883
In vitro and in silico evaluation of chromene based aroyl hydrazones as anticonvulsant agents Violina T. AngelovaYulian VoynikovJana Tchekalarova Original Research 22 April 2017 Pages: 1884 - 1896
Isolation and characterization of Streptomyces tauricus from Thajiwas glacier—a new source of actinomycin-D Shabir Ahmad RatherAabid Manzoor ShahQazi Parvaiz Hassan Original Research 26 April 2017 Pages: 1897 - 1902
QSAR and pharmacophore modeling of anti-tubercular 6-Fluoroquinolone compounds utilizing calculated structural descriptors DipikshaMohd SalmanSisir Nandi Original Research 26 April 2017 Pages: 1903 - 1914
Chemopreventive effect of saponin isolated from Gymnema sylevestre on prostate cancer through in silico and in vivo analysis Rajamanickam Pon NivedhaVenkatesan SuryanarayananManikkam Rajalakshmi Original Research 26 April 2017 Pages: 1915 - 1925
Computational insights into HER3 gatekeeper T768I resistance mutation to bosutinib in HER3-related breast cancer Chun-Ling DongFang-Chun GuoJie Xue Original Research 26 April 2017 Pages: 1926 - 1934
Synthesis and evaluation of the anticonvulsant activities of 2,3-dihydrophthalazine-1,4-dione derivatives Xiang-Jun LiuHong-Jian ZhangZhe-Shan Quan Original Research 27 April 2017 Pages: 1935 - 1946
(S,E)-2-hydroxy-N-(2-hydroxy-5-nitrobenzylidene) propane hydrazide as a quorum sensing inhibitor of Pseudomonas aeruginosa Azam HeidariFakhri HaghiRahman Bikas Original Research 28 April 2017 Pages: 1947 - 1955
Novel arylazothiazoles and arylazo[1,3,4]thiadiazoles as potential antimicrobial and anticancer agents: synthesis, molecular modeling, and biological screening Sayed M. RiyadhAnwar A. DeawalySaleh Ihmaid Original Research 02 May 2017 Pages: 1956 - 1968
Design, synthesis and QSAR studies of 2-amino benzo[d]thiazolyl substituted pyrazol-5-ones: novel class of promising antibacterial agents Mahesh B. PalkarAniket PatilRajshekhar V. Karpoormath Original Research 05 May 2017 Pages: 1969 - 1987
Development and application of novel molecular descriptors for predicting biological activity R. DuttA. K. Madan Original Research 06 May 2017 Pages: 1988 - 2006
Replacing triazole with diazole to optimize physicochemical properties of a click-based lead compound Yinping TianWenhui LvJie Shen Original Research 09 May 2017 Pages: 2007 - 2014
Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents Cem YamaliDilan Ozmen OzgunNoriyuki Okudaira Original Research 09 May 2017 Pages: 2015 - 2023
Synthesis, antioxidative and antiproliferative activity of methoxy amidino substituted benzamides and benzimidazoles Maja CindrićIrena SovićKristina Starčević Original Research 09 May 2017 Pages: 2024 - 2037
BIX-01294 inhibits oncoproteins NSD1, NSD2 and NSD3 Masayo MorishitaDamiaan E. H. F. MeviusEric di Luccio Original Research 09 May 2017 Pages: 2038 - 2047
Investigation on the effects of pomiferin from Maclura pomifera on indomethacin-induced gastric ulcer: An experimental study in rats İlyas BozkurtEsra DilekMesut Bünyami Halici Original Research 12 May 2017 Pages: 2048 - 2056
The hepatoprotective activity of a new derivative kaempferol glycoside from the leaves of Vietnamese Phyllanthus acidus (L.) Skeels Nguyen Cong Thuy TramNinh The SonDo Thi Thao Original Research 15 May 2017 Pages: 2057 - 2064
Cytotoxic activity evaluation and molecular docking study of phenolic derivatives from Achillea fragrantissima (Forssk.) growing in Egypt Basma M. AwadEman S. HabibSafwat A. Ahmed Original Research 16 May 2017 Pages: 2065 - 2073
Flavonoid rutinosides from Cinnamomum parthenoxylon leaves and their hepatoprotective and antioxidant activity Antoni PardedeMorina AdfaMamoru Koketsu Original Research 16 May 2017 Pages: 2074 - 2079
Synthesis and evaluation of novel urea and amide derivatives of 2-amino-4-phenylthiazole as potential antibacterial agents Zhi-Hua ZhangYu ChenSong You Original Research 17 May 2017 Pages: 2080 - 2087
Synthesis, biological evaluation and molecular docking studies of novel quinuclidinone derivatives as potential antimicrobial and anticonvulsant agents Krzysztof Z. ŁączkowskiKatarzyna LandowskaAnna Malm Original Research 19 May 2017 Pages: 2088 - 2104
The combination of Bleomycin with TRAIL agonists or PKC inhibitors sensitizes solid tumor cells to BLM-mediated apoptosis: new strategies to overcome chemotherapy resistance of tumors Souhir BrahimSonia ArouiAli Bettaieb Original Research 19 May 2017 Pages: 2105 - 2111
Molecular screening and analysis of novel therapeutic inhibitors against c-Jun N-terminal kinase Trinath DaggupatiKumaraswamy Naidu ChitralaSuneetha Yeguvapalli Original Research 19 May 2017 Pages: 2112 - 2118
Anti-HIV-1 and cytotoxicity of a new dimeric thiazepine alkaloid isolated from Ixora undulata Roxb. leaves Magdy M. D. MohammedKhaled M. Mohamed Original Research 20 May 2017 Pages: 2119 - 2126
Design, synthesis and in vitro evaluation of some small molecules malonyl CoA decarboxylase inhibitors containing pyrazoline scaffold and study of their binding interactions with malonyl CoA decarboxylase via preliminary docking simulation Deepali M. JagdaleC. S. Ramaa Original Research 22 May 2017 Pages: 2127 - 2140
Synthesis, in vitro antimicrobial, antioxidant, and antidiabetic activities of thiazolidine–quinoxaline derivatives with amino acid side chains Suhas A. ShintreDeresh RamjugernathNeil A. Koorbanally Original Research 22 May 2017 Pages: 2141 - 2151
Synthesis and anti(myco)bacterial activity of novel 5,5-diphenylpyrrolidine N-aroylthiourea derivatives and a functionalized hexahydro-1H-pyrrolo[1,2-c]imidazole Duygu ErşenMahmut ÜlgerYahya Nural Original Research 24 May 2017 Pages: 2152 - 2160
Synthesis and inhibitory effects of triarylpyrazoles on LPS-induced NO and PGE2 productions in RAW 264.7 macrophages Byung-Jun ParkMohammed I. El-GamalChang-Hyun Oh Original Research 29 May 2017 Pages: 2161 - 2171
(E)-2-Benzylidenecyclanones: part XIV. Study on interaction of some (E)-2-benzylidenebenzosuberone derivatives with calf thymus DNA by TLC and UV–Vis methods, a DNA cleavage study Zsuzsanna RozmerEvelin MartonPál Perjési Original Research 29 May 2017 Pages: 2172 - 2179
Design, synthesis and cytotoxic evaluation of a novel series of benzo[d]thiazole-2-carboxamide derivatives as potential EGFR inhibitors Lan ZhangXin-Shan DengChun Hu Original Research 29 May 2017 Pages: 2180 - 2189
Regioselective synthesis of some new 1,4-disubstituted sulfonyl-1,2,3-triazoles and their antibacterial activity studies Narasimha Swamy ThirukovelaShravankumar KankalaRavinder Vadde Original Research 29 May 2017 Pages: 2190 - 2195
Efficacy of extracts and iridoid glucosides from Pentas lanceolata on humoral and cell-mediated immune response of viral vaccine Howaida I. Abd-AllaHeba-tollah M. SweelamMohamed-Elamir F. Hegazy Original Research 29 May 2017 Pages: 2196 - 2204
Synthesis, characterization and biological evaluation of some new indomethacin analogs with a colon tumor cell growth inhibitory activity Sally I. Eissa Original Research 01 June 2017 Pages: 2205 - 2220