Articles

1. Methylmercury exposure at dosage conditions that do not affect growth can impair memory in adolescent mice

   • Ryota Yamagata
   • Ai Saito
   • Gi-Wook Hwang

   Original Article 27 April 2024

   

2. Publisher Correction: Short-term inhalation exposure to cigarette smoke induces oxidative stress and inflammation in lungs without systemic oxidative stress in mice

   • Yoon-Seok Seo
   • Kwang-Hoon Park
   • Moo-Yeol Lee

   Publisher Correction 23 April 2024

3. Steroidogenic cytochrome P450 enzymes as drug target

   • Changmin Kim
   • Eunseo Jeong
   • Donghak Kim

   Review Article 22 April 2024

   

4. Updates on the mechanisms of toxicities associated with monoclonal antibodies targeting growth factor signaling and immune cells in cancer

   • Miso Park
   • Ji Won Kim

   Review Article 22 April 2024

   

5. Lysine-63-linked polyubiquitination: a principal target of cadmium carcinogenesis

   • Abderrahmen Chargui

   Review Article 21 April 2024

   

6. Biosafety assessments of hexafluoropropylene trimer derivative as a fluorinated cooling fluid for electronics

   • Yi-Tong Zhou
   • Pei-Jie Zhang
   • Jin-Xuan Fan

   Original Article 17 April 2024

   

7. Risk assessment of cyclohexasiloxane D6 in cosmetic products

   • Yeonju Ko
   • Donghyeon Lim
   • Ok-Nam Bae

   Original Article 15 April 2024

8. Regulatory role of Echinochrome A in cancer-associated fibroblast-mediated lung cancer cell migration

   • Da-Young Eum
   • Chaeyoung Lee
   • Kyu Heo

   Original Article 11 April 2024

   

9. Elucidation of the effects of 2,5-hexandione as a metabolite of n-hexane on cognitive impairment in leptin-knockout mice (C57BL/6-Lepem1Shwl/Korl)

   • Hai Duc Nguyen
   • Won Hee Jo
   • Min-Sun Kim

   Original Article 09 April 2024

   

10. Roundup^® induces premature senescence of mouse granulosa cells via mitochondrial ROS-triggered NLRP3 inflammasome activation

    • Heliang Ni
    • Xiangdong Hu
    • Shuang Tang

    Original Article 29 March 2024

    

11. Evaluation of acute, 28-day, 13-week repeated dose oral toxicity and genotoxicity of a herbal extract (HemoHIM G) from Angelica sinensis, Ligusticum chuanxiong, and Peaonia lactiflora

    • Su-Bin Bak
    • Hansol Choi
    • Hak Sung Lee

    Original Article Open access 16 March 2024 Pages: 297 - 311

    

12. Pulmonary toxicity assessment of polypropylene, polystyrene, and polyethylene microplastic fragments in mice

    • Isaac Kwabena Danso
    • Jong-Hwan Woo
    • Kyuhong Lee

    Original Article Open access 08 March 2024 Pages: 313 - 323

    

13. n-Acetylcysteine protects against diazinon-induced histopathological damage and apoptosis in renal tissue of rats

    • Gaiqin Dong
    • Qingfeng Li
    • Xiaozhong Li

    Original Article 07 March 2024 Pages: 285 - 295

    

14. Short-term inhalation exposure to cigarette smoke induces oxidative stress and inflammation in lungs without systemic oxidative stress in mice

    • Yoon-Seok Seo
    • Kwang-Hoon Park
    • Moo-Yeol Lee

    Original Article 16 February 2024 Pages: 273 - 283

    

15. Concentration of polychlorinated biphenyls and risk assessment in finless porpoises from the East China Sea

    • Bingyao Chen
    • Huiping Jiang
    • Xiuqing Hao

    Original Article 15 February 2024 Pages: 259 - 271

    

16. Toxicity of a novel antifungal agent (ATB1651 gel) in Yucatan minipigs (Sus scrofa) following 4 weeks of daily dermal administration

    • Hyung-Sun Kim
    • Goo-Hwa Kang
    • Jeong Ho Hwang

    Original Article Open access 06 February 2024 Pages: 247 - 258

    

17. Baicalein inhibits IL-1β-induced extracellular matrix degradation with decreased MCP-1 expression in primary rat chondrocytes

    • InA Cho
    • Ki-Ho Chung
    • Jeong-Tae Koh

    Original Article 02 February 2024 Pages: 237 - 246

    

18. Pathological changes in various organs in HLA-B*57:01 transgenic mice with abacavir-induced skin eruption

    • Akira Kazaoka
    • Kazuyoshi Kumagai
    • Kousei Ito

    Original Article Open access 06 January 2024 Pages: 223 - 235

    

19. Efficiency of pharmaceutical toxicity prediction in computational toxicology

    • Yoshihiro Uesawa

    Invited Review 04 January 2024 Pages: 1 - 9

    

20. Catalytic enhancements in cytochrome P450 2C19 by cytochrome b₅

    • Gyu-Hyeong Lee
    • Vitchan Kim
    • Donghak Kim

    Original Article 02 January 2024 Pages: 215 - 222

    

21. A convenient spectrophotometric test for screening skin-sensitizing chemicals using reactivity with glutathione in chemico

    • Dong Ho Cha
    • Geon Ho Kim
    • Tae Cheon Jeong

    Original Article 13 December 2023 Pages: 203 - 213

    

22. Protective effect of cilostazol on vascular injury in rats with acute ischemic stroke complicated with chronic renal failure

    • Ru Sun
    • Qun Gu
    • Jingjing Min

    Original Article Open access 13 December 2023 Pages: 189 - 202

    

23. Association between urinary arsenic concentration and genetic polymorphisms in Korean adults

    • Seul-Gi Lee
    • Sang-Yong Eom
    • Jung-Duck Park

    Original Article 23 November 2023 Pages: 179 - 188

    

24. Distribution of molybdenum in soft tissues and blood of rats after intratracheal instillation of molybdenum(IV) sulfide nano- and microparticles

    • Renata Kuraś
    • Maciej Stępnik
    • Beata Janasik

    Original Article Open access 14 November 2023 Pages: 163 - 177

    

25. Comparative study on estrogen receptor alpha dimerization and transcriptional activity of parabens

    • Jong-Yeon Kim
    • Yooheon Park
    • Hae‐Jeung Lee

    Original Article 05 October 2023 Pages: 153 - 161

    

26. Molecular mechanism of empagliflozin cardioprotection in 5-fluorouracil (5-FU)-induced cardiotoxicity via modulation of SGLT2 and TNFα/TLR/NF-κB signaling pathway in rats

    • Marwa Monier Mahmoud Refaie
    • Sayed Shehata
    • Eman Shaaban Mahmoud Abd El Rahman

    Original Article Open access 03 October 2023 Pages: 139 - 151

    

27. Comparative metabolism of fargesin in human, dog, monkey, mouse, and rat hepatocytes

    • Min Seo Lee
    • Eun Jeong Park
    • Hye Suk Lee

    Original Article 26 September 2023 Pages: 125 - 137

    

28. Neurobehavioral effects of the exposure to mercury vapor and methylmercury during postnatal period on mice

    • Jin-Yong Lee
    • Minoru Yoshida
    • Chiho Watanabe

    Original Article 21 September 2023 Pages: 111 - 124

    

29. Anthraquinone as emerging contaminant: technological, toxicological, regulatory and analytical aspects

    • Alice Teresa Valduga
    • Itamar Luís Gonçalves
    • Edy Sousa de Brito

    Review Article 04 September 2023 Pages: 11 - 21

    

30. Naringenin suppresses aluminum-induced experimental hepato-nephrotoxicity in mice through modulation of oxidative stress and inflammation

    • Ravina Rai
    • Zaved Ahmad
    • Siddhartha Kumar Mishra

    Original Article 01 September 2023 Pages: 97 - 110

    

31. Phloretin targets SIRT1 to alleviate oxidative stress, apoptosis, and inflammation in deep venous thrombosis

    • Xiaodong Wang
    • Jin Yan
    • Yin Ying

    Original Article 30 August 2023 Pages: 83 - 96

    

32. YPEL3 expression induces cellular senescence via the Hippo signaling pathway in human breast cancer cells

    • Yeonju Kwon
    • Hyein Lee
    • Young-Jin Chun

    Original Article 24 August 2023 Pages: 711 - 719

    

33. Chemerin/CMKLR1 pathway exacerbates cisplatin-induced spiral ganglion neuron injury

    • Jie Tian
    • Ying Mu
    • Lili Ma

    Original Article 24 August 2023 Pages: 73 - 81

    

34. Assessment of reproductive toxicity of gold nanoparticles and its reversibility in male albino rats

    • Nancy A. Abdulhaq
    • Dina A. Elnady
    • Seham A. Gad El-Hak

    Original Article Open access 23 August 2023 Pages: 57 - 72

    

35. Kaempferol induces apoptosis through the MAPK pathway and regulates JNK-mediated autophagy in MC-3 cells

    • Su-Ji Jeon
    • Gi-Hwan Jung
    • Ji-Youn Jung

    Original Article 11 August 2023 Pages: 45 - 55

    

36. Potential role of inducible nitric oxide synthase (iNOS) activity in testicular dysfunction following co-administration of alcohol and combination antiretroviral therapy (cART) in diabetic rats: an immunohistochemistry study

    • Elna Owembabazi
    • Pilani Nkomozepi
    • Ejikeme F. Mbajiorgu

    Original Article Open access 03 August 2023 Pages: 31 - 43

    

37. Re-evaluation of a microbiological acceptable daily intake for tylosin based on its impact on human intestinal microflora

    • Min Ji Kim
    • Ji Young Kim
    • Guiim Moon

    Original Article Open access 02 August 2023 Pages: 23 - 30

    

38. Effects of toxicants on endoplasmic reticulum stress and hepatic cell fate determination

    • Jihoon Tak
    • Sang Geon Kim

    Invited Review 26 July 2023 Pages: 533 - 547

    

39. Molecular mechanisms of 1,2-dichloroethane-induced neurotoxicity

    • Yang Xiang
    • Xiaoshun Zhang
    • Xiaojing Meng

    Review Article 13 July 2023 Pages: 565 - 574

    

40. Effects of grape seed proanthocyanidin extract on side effects of high-dose methylprednisolone administration in male rats

    • Aslihan Sur
    • Seda Iflazoglu Mutlu
    • Selim Esen

    Original Article 07 July 2023 Pages: 749 - 759

    

41. Association of immunotoxicological indices with lung cancer biomarkers in poultry, grape, and rose farming workers

    • Anju Maharjan
    • Ravi Gautam
    • Yong Heo

    Original Article 29 June 2023 Pages: 739 - 747

    

42. Protective effects of cardamom aqueous extract against tamoxifen-induced pancreatic injury in female rats

    • Hala Attia
    • Afraa Alzoubi
    • Rehab Ali

    Original Article 27 June 2023 Pages: 721 - 737

    

43. Two weeks dose range-finding and four weeks repeated dose oral toxicity study of a novel reversible monoamine oxidase B inhibitor KDS2010 in cynomolgus monkeys

    • Kyung-Tai Kim
    • Doo-Wan Cho
    • Su-Cheol Han

    Original Article 24 June 2023 Pages: 693 - 709

    

44. Integrative roles of sphingosine kinase in liver pathophysiology

    • Kyu Min Kim
    • Eun Jin Shin
    • Sung Hwan Ki

    Review Article 19 June 2023 Pages: 549 - 564

    

45. A regional approach for health risk assessment of toxicants in plastic food containers

    • Lan Binh Thi Nguyen
    • Nguyen Thi Thanh Truc
    • Byeong-Kyu Lee

    Original Article 17 June 2023 Pages: 681 - 692

    

46. AXL is required for hypoxia-mediated hypoxia-inducible factor-1 alpha function in glioblastoma

    • Thuy-Trang T. Vo
    • Quangdon Tran
    • Jongsun Park

    Original Article 14 June 2023 Pages: 669 - 679

    

47. Oxygen consumption rate to evaluate mitochondrial dysfunction and toxicity in cardiomyocytes

    • Dohee Ahn
    • Ryeo-Eun Go
    • Kyung-Chul Choi

    Invited Review 13 June 2023 Pages: 333 - 339

    

48. Acute toxicity assessment of nine organic UV filters using a set of biotests

    • Stec Marcin
    • Astel Aleksander

    Original Article Open access 12 June 2023 Pages: 649 - 667

    

49. Atg5 knockout induces alternative autophagy via the downregulation of Akt expression

    • Hye-Gyo Kim
    • Myeong-Han Ro
    • Michael Lee

    Original Article 05 June 2023 Pages: 637 - 647

    

50. Endotoxin of Porphyromonas gingivalis amplifies the inflammatory response in hyperglycemia-induced zebrafish through a mechanism involving chitinase-like protein YKL-40 analogs

    • Gizem Gündüz
    • Merih Beler
    • Kemal Naci Kose

    Original Article 31 May 2023 Pages: 625 - 636