1. Antibacterial Dosing in Intensive Care

   • Jason A. Roberts
   • Jeffrey Lipman

   Current Opinion 30 September 2012 Pages: 755 - 773

   

2. Chronopharmacokinetics of Ciclosporin and Tacrolimus

   • Massimo Baraldo
   • Mario Furlanut

   Leading Article 30 September 2012 Pages: 775 - 788

   

3. Lack of Pharmacokinetic Interaction for ISIS 113715, a 2′-0-Methoxyethyl Modified Antisense Oligonucleotide Targeting Protein Tyrosine Phosphatase 1B Messenger RNA, with Oral Antidiabetic Compounds Metformin, Glipizide or Rosiglitazone

   • Richard S. Geary
   • Joann D. Bradley
   • Andrè A. van Vliet

   Original Research Article 30 September 2012 Pages: 789 - 801

   

4. Population Pharmacokinetics of Melagatran, the Active Form of the Oral Direct Thrombin Inhibitor Ximelagatran, in Atrial Fibrillation Patients Receiving Long-Term Anticoagulation Therapy

   • Sofie Bååthe
   • Bengt Hamrén
   • Ulf G. Eriksson

   Original Research Article 30 September 2012 Pages: 803 - 819

   

5. Pharmacokinetics, Pharmacodynamics and Safety of Febuxostat, a Non-Purine Selective Inhibitor of Xanthine Oxidase, in a Dose Escalation Study in Healthy Subjects

   • Reza Khosravan
   • Brian A. Grabowski
   • Laurent Vernillet

   Original Research Article 30 September 2012 Pages: 821 - 841

   

6. Comparison of Equivalent Doses of Fentanyl Buccal Tablets and Arteriovenous Differences in Fentanyl Pharmacokinetics

   • Mona Danvish
   • Mary Kirby
   • John G. Jiang

   Original Research Article 30 September 2012 Pages: 843 - 850

   

7. Parametric and Nonparametric Population Methods

   • Johannes H. Proost
   • Douglas J. Eleveld

   Correspondence 30 September 2012 Pages: 851 - 852

   

8. The Author’s Reply

   • Roger Jelliffe

   Correspondence 30 September 2012 Pages: 852 - 854