Stage-dependent immunity orchestrates AQP4 antibody-guided NMOSD pathology: a role for netting neutrophils with resident memory T cells in situ Akihiro NakajimaFumihiro YanagimuraIzumi Kawachi Original Paper 24 April 2024 Article: 76
BTK inhibition limits microglia-perpetuated CNS inflammation and promotes myelin repair Anastasia GeladarisSebastian TorkeMartin S. Weber Original Paper Open access 24 April 2024 Article: 75
Nanopore sequencing from formalin-fixed paraffin-embedded specimens for copy-number profiling and methylation-based CNS tumor classification Ann-Kristin AfflerbachAnne AlbersChristian Thomas Correspondence Open access 20 April 2024 Article: 74
Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion Evan UdineMariely DeJesus-HernandezMarka van Blitterswijk Original Paper Open access 19 April 2024 Article: 73
Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects Esmat KarimiJochen GohlkeHenk Granzier Original Paper Open access 18 April 2024 Article: 72
Histologic correlates of “Choroidal abnormalities” in Neurofibromatosis type 1 (NF1) Anat O. Stemmer-RachamimovLiana KozannoJoseph F. 3rd Rizzo Original Paper 12 April 2024 Article: 71
Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease Prabesh BhattaraiTamil Iniyan GunasekaranBadri N. Vardarajan Original Paper Open access 10 April 2024 Article: 70
Regulated cell death and its role in Alzheimer’s disease and amyotrophic lateral sclerosis Dietmar Rudolf ThalKlara GaworSebastiaan Moonen Review 07 April 2024 Article: 69
Metabologenomic characterization uncovers a clinically aggressive IDH mutant glioma subtype Farshad NassiriAndrew AjisebutuGelareh Zadeh Original Paper 07 April 2024 Article: 68
Altered TFEB subcellular localization in nigral neurons of subjects with incidental, sporadic and GBA-related Lewy body diseases Tim E. MoorsMartino L. MorellaWilma D. J. van de Berg Original Paper Open access 06 April 2024 Article: 67
Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimer’s disease and related dementias Methasit Jaisa-aadClara Muñoz-CastroAlberto Serrano-Pozo Original Paper Open access 03 April 2024 Article: 66
Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer’s disease reveals distinct sequential responses to Aβ and tau Astrid WachterMaya E. WoodburyBradley T. Hyman Original Paper Open access 01 April 2024 Article: 65
Microglial phagolysosome dysfunction and altered neural communication amplify phenotypic severity in Prader-Willi Syndrome with larger deletion Felipe Correa-da-SilvaJenny CarterChun-Xia Yi Original Paper Open access 31 March 2024 Article: 64
Correction to: MET receptor serves as a promising target in melanoma brain metastases Torben RedmerElisa SchumannJosefine Radke Correction Open access 27 March 2024 Article: 63
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice Tuancheng FengHuan DuFenghua Hu Original Paper 25 March 2024 Article: 62
TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy George A. Edwards IIICaleb A. WoodJoanna L. Jankowsky Original Paper 25 March 2024 Article: 61
A muscarinic receptor antagonist reverses multiple indices of diabetic peripheral neuropathy: preclinical and clinical studies using oxybutynin Carolina M. CasseliniHenri K. ParsonNigel A. Calcutt Original Paper 25 March 2024 Article: 60
Correction: Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-truncted Abeta in sporadic Alzheimer disease cases and mouse models Yvonne BouterJose Socrates Lopez NoguerolaThomas A. Bayer Correction 25 March 2024 Article: 59
Disentangling and quantifying the relative cognitive impact of concurrent mixed neurodegenerative pathologies Carolina Maldonado-DíazSatomi HiyaTimothy E. Richardson Original Paper Open access 23 March 2024 Article: 58
Gene transcript fusions are associated with clinical outcomes and molecular groups of meningiomas Naomi ZakimiMinh P. NguyenDavid R. Raleigh Correspondence Open access 20 March 2024 Article: 57
Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia Christine MarquesAaron HeldBrian J. Wainger Original Paper Open access 13 March 2024 Article: 56
MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons Hong XuQi QiuVirginia M.-Y. Lee Original Paper Open access 12 March 2024 Article: 55
Role of GBA variants in Lewy body disease neuropathology Ronald L. WaltonShunsuke KogaMichael G. Heckman Original Paper 12 March 2024 Article: 54
Alteration of LARGE1 abundance in patients and a mouse model of 5q-associated spinal muscular atrophy Andreas RoosLinda-Isabell SchmittTim Hagenacker Original Paper Open access 12 March 2024 Article: 53
Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease Jarod RutledgeBenoit LehallierKathleen L. Poston Original Paper Open access 11 March 2024 Article: 52
The prevalence and topography of spinal cord demyelination in multiple sclerosis: a retrospective study Alex D. WaldmanCecilia CataniaGabriele C. DeLuca Original Paper Open access 09 March 2024 Article: 51
RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS Holly SpenceFergal M. WaldronJenna M. Gregory Original Paper Open access 05 March 2024 Article: 50
Methylation class oligosarcoma, IDH-mutant could exhibit astrocytoma-like molecular features Lingyu LiuYuqing LiuKe-Nan Zhang Correspondence 05 March 2024 Article: 49
Astroglial calcium signaling and homeostasis in tuberous sclerosis complex Alessia RomagnoloGiulia DematteisEleonora Aronica Original Paper Open access 28 February 2024 Article: 48
Disruption of the blood–brain barrier is correlated with spike endocytosis by ACE2 + endothelia in the CNS microvasculature in fatal COVID-19. Scientific commentary on "Detection of blood–brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2” Cynthia MagroEsmerina TiliGerard Nuovo Correspondence 27 February 2024 Article: 47
Myofiber-type-dependent ‘boulder’ or ‘multitudinous pebble’ formations across distinct amylopectinoses Sharmistha MitraBaozhi ChenBerge A. Minassian Original Paper 27 February 2024 Article: 46
Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE Abigail AlexanderVictor E. AlvarezThor D. Stein Original Paper 26 February 2024 Article: 45
MET receptor serves as a promising target in melanoma brain metastases Torben RedmerElisa SchumannJosefine Radke Original Paper Open access 22 February 2024 Article: 44
Canine meningiomas are comprised of 3 DNA methylation groups that resemble the molecular characteristics of human meningiomas Naomi ZakimiChristina N. MazckoDavid R. Raleigh Correspondence Open access 20 February 2024 Article: 43
Aggressive human MenG C meningiomas have a molecular counterpart in canines Akdes S. HarmanciBeth BoudreauAkash J. Patel Correspondence 20 February 2024 Article: 42
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport Paraskevi TziortzoudaJolien SteyaertLudo Van Den Bosch Original Paper Open access 16 February 2024 Article: 41
Regional AT-8 reactive tau species correlate with intracellular Aβ levels in cases of low AD neuropathologic change Nauman MalikMohi-Uddin MiahDavid J. Koss Original Paper Open access 14 February 2024 Article: 40
The contribution of β-amyloid, Tau and α-synuclein to blood–brain barrier damage in neurodegenerative disorders Ying-Chieh WuTizibt Ashine BogaleArianna Bellucci Review Open access 12 February 2024 Article: 39
Endothelial cells and macrophages as allies in the healthy and diseased brain Adam DenesCathrin E. HansenMarkus Schwaninger Review Open access 12 February 2024 Article: 38
The niche matters: origin, function and fate of CNS-associated macrophages during health and disease Adrià Dalmau GasullMartina GlavanMarco Prinz Review Open access 12 February 2024 Article: 37
Macrophages and endothelial cells in the neurovascular unit Jan WenzelMarkus Schwaninger Editorial Open access 12 February 2024 Article: 36
Reply: pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion Ramin RahmanzadeFelix Sahm Correspondence Open access 10 February 2024 Article: 35
Pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion. Scientific commentary on ‘Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics’ Alexandre Vasiljevic Correspondence Open access 10 February 2024 Article: 34
“RYR1 and the cerebellum”: scientific commentary on “Defective Cerebellar Ryanodine Receptor Type 1 and Endoplasmic Reticulum Calcium ‘Leak’ in Tremor Pathophysiology” Heinz JungbluthDennis T. FamiliNicol C. Voermans Correspondence Open access 07 February 2024 Article: 33
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease Martí Colom-CadenaJamie ToombsTara L. Spires-Jones Original Paper Open access 06 February 2024 Article: 32
New insights into neuropathology and pathogenesis of autoimmune glial fibrillary acidic protein meningoencephalomyelitis Yong GuoVerena EndmayrRomana Höftberger Original Paper Open access 03 February 2024 Article: 31
Scientific commentary on: “Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer’s disease and primary tauopathies” Frederike C. OertelDaniel CasillasAri J. Green Correspondence Open access 03 February 2024 Article: 30
Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains Mingee ChungE. Kathleen CarterZachary T. McEachin Original Paper Open access 03 February 2024 Article: 29
Neuroinflammatory disease signatures in SPG11-related hereditary spastic paraplegia patients Laura KrummTatyana PoznerMartin Regensburger Original Paper Open access 02 February 2024 Article: 28
Similar brain proteomic signatures in Alzheimer’s disease and epilepsy Dominique LeitnerGeoffrey PiresEleanor Drummond Original Paper Open access 30 January 2024 Article: 27
