Pharmacodynamics of DT-IgG, a dual-targeting antibody against VEGF-EGFR, in tumor xenografted mice Selwyn J. HurwitzHongzheng ZhangDong M. Shin Original Article 13 September 2011 Pages: 577 - 590
A phase I study of daily everolimus plus low-dose weekly cisplatin for patients with advanced solid tumors Matthew G. FuryEric ShermanDavid Pfister Original Article 13 September 2011 Pages: 591 - 598
Evaluation of a formula for individual dosage of nedaplatin based on renal function Shinya SatoHiroyuki FujiwaraJunzo Kigawa Original Article 15 September 2011 Pages: 599 - 603
An open-label study to describe pharmacokinetic parameters of erlotinib in patients with advanced solid tumors with adequate and moderately impaired hepatic function Cindy L. O’BryantPaul HaluskaSuresh Ramalingam Original Article 22 September 2011 Pages: 605 - 612
Adjuvant therapy for resectable high-risk soft tissue sarcoma: feasibility and efficacy of a sandwich chemoradiotherapy strategy Christian H. BrandtsChristiane SchulzMichael Thomas Original Article 24 September 2011 Pages: 613 - 620
Targeting autophagy enhances BO-1051-induced apoptosis in human malignant glioma cells Pei-Ming ChuLi-Hsin ChenShih-Hwa Chiou Original Article 27 September 2011 Pages: 621 - 633
Phase II study of weekly docetaxel and fixed dose rate gemcitabine in patients with previously treated advanced soft tissue and bone sarcoma Eun Mi LeeSun Young RhaJin-Hee Ahn Original Article 30 September 2011 Pages: 635 - 642
Pharmacokinetics of TH-302: a hypoxically activated prodrug of bromo-isophosphoramide mustard in mice, rats, dogs and monkeys Donald JungLin LinM. Matteucci Original Article 01 October 2011 Pages: 643 - 654
Phase II study of use of a single cycle of induction chemotherapy and concurrent chemoradiotherapy containing capecitabine/cisplatin followed by surgery for patients with resectable esophageal squamous cell carcinoma: long-term follow-up data Dong Hoe KooSeung-Il ParkSung-Bae Kim Original Article 04 October 2011 Pages: 655 - 663
Debio 0507 primarily forms diaminocyclohexane-Pt-d(GpG) and -d(ApG) DNA adducts in HCT116 cells C. L. KingS. RamachandranM. Barbier Original Article 04 October 2011 Pages: 665 - 677
Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice Liu ZhongfaMing ChiuKenneth K. Chan Original Article 04 October 2011 Pages: 679 - 689
The role of MTHFR and RFC1 polymorphisms on toxicity and outcome of adult patients with hematological malignancies treated with high-dose methotrexate followed by leucovorin rescue Patrizia ChiusoloSabrina GiammarcoSimona Sica Original Article 09 October 2011 Pages: 691 - 696
In vitro evaluation of clinical activity and toxicity of anticancer drugs using tumor cells from patients and cells representing normal tissues Caroline HaglundAnna Ã…leskogElin Lindhagen Original Article 09 October 2011 Pages: 697 - 707
A phase I dose-escalation and pharmacokinetic study of sunitinib in combination with pemetrexed in patients with advanced solid malignancies, with an expanded cohort in non-small cell lung cancer L. Q. M. ChowN. BlaisD. R. Camidge Original Article Open access 12 October 2011 Pages: 709 - 722
miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP Wei ZhuHuaguo XuPing Liu Original Article 13 October 2011 Pages: 723 - 731
First-time-in-human study of GSK923295, a novel antimitotic inhibitor of centromere-associated protein E (CENP-E), in patients with refractory cancer Vincent ChungElisabeth I. HeathKyle D. Holen Original Article 22 October 2011 Pages: 733 - 741
A randomized phase II study of two doses of vorinostat in combination with 5-FU/LV in patients with refractory colorectal cancer M. G. FakihA. GromanJ. R. Muindi Original Article 22 October 2011 Pages: 743 - 751
Effect of food and a proton pump inhibitor on the pharmacokinetics of S-1 following oral administration of S-1 in patients with advanced solid tumors Max E. ScheulenKaku SaitoDirk Strumberg Original Article 22 October 2011 Pages: 753 - 761
Phase I rapid dose-escalation study of AGS-1C4D4, a human anti-PSCA (prostate stem cell antigen) monoclonal antibody, in patients with castration-resistant prostate cancer: a PCCTC trial Emmanuel S. AntonarakisMichael A. CarducciMichael J. Morris Original Article 22 October 2011 Pages: 763 - 771
Phase II trial of sorafenib in combination with 5-fluorouracil infusion in advanced hepatocellular carcinoma Iacopo PetriniMonica LencioniSergio Ricci Original Article 28 October 2011 Pages: 773 - 780
Intrapleural paclitaxel for malignant pleural effusion from ovarian and breast cancer: a phase II study with pharmacokinetic analysis Giuseppe LombardiMaria Ornella NicolettoVittorina Zagonel Original Article 29 October 2011 Pages: 781 - 787
Pharmacokinetics, metabolism and excretion of [14C]-lenalidomide following oral administration in healthy male subjects Nianhang ChenLian WenGondi Kumar Original Article Open access 29 October 2011 Pages: 789 - 797
ABT-263 sensitizes TRAIL-resistant hepatocarcinoma cells by downregulating the Bcl-2 family of anti-apoptotic protein Guan WangYao ZhanWenhua Li Original Article 29 October 2011 Pages: 799 - 805
Feasibility of biweekly combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in patients with metastatic solid tumors: results of a two-step phase I trial: XELIRI and XELIRINOX T. MazardM. YchouE. Assenat Original Article 30 October 2011 Pages: 807 - 814
A phase I pharmacokinetic study of bexarotene with vinorelbine and cisplatin in patients with advanced non-small-cell lung cancer (NSCLC) Heather A. WakeleeGary MiddletonCharlotte D. Jacobs Clinical Trial Report 06 November 2011 Pages: 815 - 824
A phase I pharmacokinetic study of bexarotene with paclitaxel and carboplatin in patients with advanced non-small cell lung cancer (NSCLC) Jordi RodonCharlotte D. JacobsHeather A. Wakelee Clinical Trial Report 06 November 2011 Pages: 825 - 834
A phase I and pharmacokinetic study of oral 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) in the treatment of advanced-stage solid cancers: a California Cancer Consortium Study Joseph ChaoTimothy W. SynoldYun Yen Clinical Trial Report 22 November 2011 Pages: 835 - 843
Pharmacokinetics of carboplatin in a hemodialysis patient with small-cell lung cancer Mikako HiraikeYoichi HirakiKosuke Kashiwabara Short Communication 23 December 2011 Pages: 845 - 848