1. Population approaches in drug development

   • L. Aarons
   • L. P. Balant
   • S. Vozeh

   Conference Report Pages: 389 - 391

2. Age standardisation of drug utilisation: comparisons of different methods using cardiovascular drug data from Sweden and Spain

   • J. Merlo
   • J. Ranstam
   • A. Melander

   Originals Pages: 393 - 398

3. Esmolol, an ultrashort-acting, selective β₁-adrenoceptor antagonist: pharmacodynamic and pharmacokinetic properties

   • C. Volz-Zang
   • B. Eckrich
   • D. Palm

   Originals Pages: 399 - 404

4. The effect of the gastrointestinal lipase inhibitor, orlistat, on serum lipids and lipoproteins in patients with primary hyperlipidaemia

   • S. Tonstad
   • D. Pometta
   • P. van der Wal

   Originals Pages: 405 - 410

5. Serum glucose, insulin and C-peptide response to oral glucose after intravenous administration of hydrocortisone and methylprednisolone in man

   • A. Bruno
   • P. Carucci
   • G. Pagano

   Originals Pages: 411 - 415

6. Characterization of cyclosporine a uptake in human erythrocytes

   • C. Reichel
   • M. von Falkenhausen
   • H. J. Dengler

   Originals Pages: 417 - 419

7. Growth hormone-releasing activity of hexarelin in humans

   • B. P. Imbimbo
   • T. Mant
   • R. Deghenghi

   Originals Pages: 421 - 425

8. Antihypertensive efficacy of twice daily controlled release diltiazem using 24 hour intra-arterial blood pressure monitoring

   • B. S. Sridhara
   • P. Thomas
   • E. B. Raftery

   Originals Pages: 427 - 430

9. Metabolic effects of long-term angiotensin-converting enzyme inhibition with fosinopril in patients with essential hypertension: relationship to angiotensin-converting enzyme inhibition

   • R. Reneland
   • P.-E. Andersson
   • H. Lithell

   Originals Pages: 431 - 436

10. Effects of glycopyrrolate on capsaicin-induced cough in normal volunteers treated with captopril

    • M. van Wyk
    • K. De Sommers
    • J. R. Snyman

    Originals Pages: 437 - 439

11. Dexfenfluramine-induced prolactin release as an index of central synaptosomal 5-hydroxytryptamine during treatment with fluoxetine

    • K. De Sommers
    • M. van Wyk
    • J. R. Snyman

    Originals Pages: 441 - 444

12. Fluvastatin efficacy and tolerability in comparison and in combination with cholestyramine

    • E. Hagen
    • H. Istad
    • P. Pfister

    Originals Pages: 445 - 449

13. Paracetamol pharmacokinetics during the first trimester of human pregnancy

    • L. Beaulac-Baillargeon
    • S. Rocheleau

    Originals Pages: 451 - 454

14. The effect of ciclotropium on human heart rate

    • R. W. Ding
    • R. E. Port
    • E. Weber

    Originals Pages: 455 - 459

15. Single dose human pharmacology of umespirone

    • R. L. Holland
    • K. Wesnes
    • B. Dietrich

    Originals Pages: 461 - 468

16. Insulin concentrations and insulin sensitivity after short-term amiloride in healthy subjects

    • J. W. Eriksson
    • J. Fowelin
    • V. Urbanavicius

    Short Communications Pages: 469 - 472

17. Urinary excretion of phenobarbitone and its metabolites in chronically treated patients

    • I. Bernus
    • R. G. Dickinson
    • M. J. Eadie

    Short Communications Pages: 473 - 475

18. The quinolone, flumequine, has no effect on theophylline pharmacokinetics

    • B. Lacarelle
    • O. Blin
    • A. Durand

    Short Communications Pages: 477 - 478

19. Do the penicillin antibiotics interact with digoxin?

    • K. M. Rhodes
    • S. N. Brown

    Letters To The Editors Pages: 479 - 480

20. Genetically determined sparteine oxidation polymorphism in a Polish population

    • K. Orzechowska-Juzwenko
    • J. Pawlik
    • Z. Hora

    Letters To The Editors Pages: 481 - 483

21. Influence of halothane anaesthesia on protein binding of drugs

    • R. Calvo
    • E. Suárez
    • J. M. Rodríguez Sasiaín

    Letters To The Editors Pages: 484 - 484

22. Announcements

    Announcement Pages: 485 - 485