1. Local mechanisms that regulate bone formation: The subject of a recent NIH-sponsored workshop

   • W. A. Peck
   • A. H. Reddi
   • S.L Gordon

   Editorial Pages: 1 - 3

2. Corticosteroids and bone

   • W. Peck
   • C. Gennari
   • L. V. Avioli

   Round Table Discussion Pages: 4 - 7

3. Total body and regional bone mineral by dual-photon absorptiometry in metabolic bone disease

   • R. B. Mazess
   • W. W. Peppler
   • E. Smith Jr.

   Clinical Investigations Pages: 8 - 13

4. Total body calcium mass in primary hyperparathyroidism and long-term changes

   • L. E. Jimenez
   • T. J. Spinks
   • G. F. Joplin

   Clinical Investigations Pages: 14 - 18

5. Serum vitamin D metabolites in younger and elderly postmenopausal women

   • Claus Christiansen
   • Paul Rødbro

   Clinical Investigations Pages: 19 - 24

6. The influence of age and sex on bone resorption of secondary hyperparathyroidism in renal osteodystrophy

   • H. Erik Meema
   • Dimitrios G. Oreopoulos
   • P. Robert Uldall

   Clinical Investigations Pages: 25 - 30

7. Evidence for an extracellular plasmin-dependent proteolytic system in mineralizing matrices

   • Rodney Michael Robinson
   • Robert Edward Taylor
   • Henning Birkedal-Hansen

   Clinical Investigations Pages: 31 - 38

8. Transmission electron microscopic study of calcium phosphate formation in supersaturated solutions seeded with apatite

   • Y. Doi
   • E. D. Eanes

   Clinical Investigations Pages: 39 - 47

9. Adsorption of molecules of biological interest onto hydroxyapatite

   • E. C. Moreno
   • M. Kresak
   • D. I. Hay

   Clinical Investigations Pages: 48 - 59

10. Role of acid phosphate in hydroxyapatite lattice expansion

    • R. A. Young
    • D. W. Holcomb

    Clinical Investigations Pages: 60 - 63

11. Solubility of calcium salts, enamel, and hydroxyapatite in aqueous solutions of simple carbohydrates

    • Kauko K. Mäkinen
    • Eva Söderling

    Clinical Investigations Pages: 64 - 71

12. The effects of prostaglandin E₂, parathyroid hormone, 1,25 dihydroxycholecalciferol, and cyclic nucleotide analogs on alkaline phosphatase activity in osteoblastic cells

    • M. Kumegawa
    • E. Ikeda
    • M. Hiramatsu

    Clinical Investigations Pages: 72 - 76

13. Assessment of anin vivo diffusion chamber method as a quantitative assay for osteogenesis

    • I. Bab
    • B. A. Ashton
    • M. E. Owen

    Clinical Investigations Pages: 77 - 82

14. Distribution of fibroblastic colony-forming cells in rabbit bone marrow and assay of their osteogenic potential by anin vivo diffusion chamber method

    • B. A. Ashton
    • C. C. Eaglesom
    • M. E. Owen

    Clinical Investigations Pages: 83 - 86

15. Divergent effects of forskolin on 3′,5′ cyclic adenosine monophosphate production and parathyroid hormone secretion

    • Larry K. Cantley
    • Drusilla L. Scott
    • David A. Ontjes

    Clinical Investigations Pages: 87 - 94

16. Stereological studies on the epiphyseal growth plate in low phosphate, vitamin D-deficiency rickets with special reference to the distribution of matrix vesicles

    • Finn P. Reinholt
    • Anders Hjerpe
    • Bengt Engfeldt

    Clinical Investigations Pages: 95 - 101

17. Effect of cartilage-derived factor on DNA and protein synthesis in cultured rat calvariae

    • Ernesto Canalis
    • Yukio Kato
    • Fujio Suzuki

    Clinical Investigations Pages: 102 - 107

18. The subcellular distribution of [¹⁴C]dichloromethylenebisphosphonate and [¹⁴C]1-hydroxyethylidene-1,1-bisphosphonate in cultured calvaria cells

    • Rolf Felix
    • Harald L. Guenther
    • Herbert Fleisch

    Clinical Investigations Pages: 108 - 113

19. The influence of dihydroxylated vitamin D metabolites on bone formation in the chick

    • Ian R. Dickson
    • Alan K. Hall
    • Sohan S. Jande

    Clinical Investigations Pages: 114 - 122

20. Clomiphene protects against osteoporosis in the mature ovariectomized rat

    • Paula T. Beall
    • Lalith K. Misra
    • Adrian LeBlanc

    Rapid Communications Pages: 123 - 125

21. Presence of lysinoalanine and histidinoalanine in bovine dentin phosphoprotein

    • Yoshinori Kuboki
    • Ryuichi Fujisawa
    • Satoshi Sasaki

    Rapid Communications Pages: 126 - 128

22. Vitamin-D-dependent calcium-binding-protein and parvalbumin occur in bones and teeth

    • M. R. Celio
    • A. W. Norman
    • C. W. Heizmann

    Rapid Communications Pages: 129 - 130

23. Announcements

    Announcement Pages: 131 - 132

24. Effect of aluminum and parathyroid hormone on osteoblasts and bone mineralization in chronic renal failure

    • Colin R. Dunstan
    • Richard A. Evans
    • Allen C. Alfrey

    Clinical Investigations Pages: 133 - 138

25. Effects of weight loss on serum 1,25-(OH)₂-vitamin D concentrations in adults: A preliminary report

    • J. Lemann Jr.
    • R. W. Gray
    • N. D. Adams

    Clinical Investigations Pages: 139 - 144

26. Comparative study of deflazacort, a new synthetic corticosteroid, and dexamethasone on the synthesis of collagen in different rat bone cell populations and rabbit articular chondrocytes

    • H. L. Guenther
    • R. Felix
    • H. Fleisch

    Laboratory Investigations Pages: 145 - 152

27. Glucocorticoids increase the 1,25(OH)₂D₃ receptor concentration in rat osteogenic sarcoma cells

    • Stavros C. Manolagas
    • Jean Abare
    • Leonard J. Deftos

    Laboratory Investigations Pages: 153 - 157

28. Effect of cortisol on periosteal and nonperiosteal collagen and DNA synthesis in cultured rat calvariae

    • Ernesto Canalis

    Laboratory Investigations Pages: 158 - 166

29. Electromagnetic modulation of biological processes: Influence of culture media and significance of methodology in the Ca-uptake by embryonal chick tibiain vitro

    • Giuseppe Colacicco
    • Arthur A. Pilla

    Laboratory Investigations Pages: 167 - 174

30. Arachidonate metabolism during chondrogenesisin vitro

    • Kenneth P. Chepenik
    • Wai Chang Ho
    • Curtis L. Parker

    Laboratory Investigations Pages: 175 - 181

31. Differential response in alveolar bone osteoclasts residing at two different bone sites

    • Chung-Ching Liu
    • David J. Baylink

    Laboratory Investigations Pages: 182 - 188

32. Protamine: A powerfulin vivo inhibitor of bone resorption

    • Martha Potts
    • Samuel Doppelt
    • John T. Potts Jr.

    Laboratory Investigations Pages: 189 - 193

33. Benzo(B)Thiophene-2-Carboxylic acid: Calcium uptake and cyclic AMP production in isolated bone cells

    • J. C. Robin
    • M. J. Brown
    • R. M. Dziak

    Laboratory Investigations Pages: 194 - 199

34. Effects of vitamin D₃ metabolites on calcium fluxes in intact chicken skeletal muscle and myoblasts culturedin vitro

    • Daniel L. Giuliani
    • Ricardo L. Boland

    Laboratory Investigations Pages: 200 - 205

35. 24,25(OH)₂D₃, bone formation, and bone resorption in vitamin D-deficient, azotemic rats

    • W. G. Goodman
    • D. J. Baylink
    • D. J. Sherrard

    Laboratory Investigations Pages: 206 - 213

36. Co-isolation of proteolipids and calcium-phospholipid-phosphate complexes

    • B. D. Boyan
    • A. L. Boskey

    Laboratory Investigations Pages: 214 - 218

37. High-resolution electron microscopy of octacalcium phosphate and its hydrolysis products

    • D. G. A. Nelson
    • J. D. McLean

    Laboratory Investigations Pages: 219 - 232

38. Effects on fracture healing of an antagonist of the vitamin K cycle

    • R. A. Dodds
    • A. Catterall
    • J. Chayen

    Laboratory Investigations Pages: 233 - 238

39. Systematic purification of free and matrix-bound phosphophoryns of bovine dentin: Presence of matrix-bound phosphophoryn as a distinct molecular entity

    • Ryuichi Fujisawa
    • Tohru Takagi
    • Satoshi Sasaki

    Laboratory Investigations Pages: 239 - 242

40. Announcements

    Announcement Pages: 243 - 244

41. Effects of prednisone and deflazacort on mineral metabolism and parathyroid hormone activity in humans

    • C. Gennari
    • B. Imbimbo
    • L. V. Avioli

    Clinical Investigations Pages: 245 - 252

42. Primary hyperparathyroidism is associated with decreased insulin receptor binding and glucose intolerance

    • R. Prager
    • G. Schernthaner
    • R. Willvonseder

    Clinical Investigations Pages: 253 - 258

43. Isolation of phosphophoryn from human dentin organic matrix

    • Yuzo Takagi
    • Arthur Veis

    Clinical Investigations Pages: 259 - 265

44. Vitamin D deficiency in mothers of rachitic infants

    • Abdelwahab T. H. Elidrissy
    • Saleh H. Sedrani
    • David E. M. Lawson

    Clinical Investigations Pages: 266 - 268

45. Mineral loss in cortical and trabecular bone during high-dose prednisone treatment

    • H. Rickers
    • Aa. Deding
    • P. Rødbro

    Clinical Investigations Pages: 269 - 273

46. Extrarenal metabolism of 25-hydroxycholecalciferol in the rat: Regulation by 1,25-dihydroxycholecalciferol

    • Russell T. Turner
    • Richard C. Avioli
    • Norman H. Bell

    Laboratory Investigations Pages: 274 - 278

47. Adriamycin inhibits PTH-mediated but not PGE₂-mediated stimulation of cyclic AMP formation in isolated bone cells

    • Gail Kohler
    • Victor Shen
    • William A. Peck

    Laboratory Investigations Pages: 279 - 284

48. The inhibitory effect of cartilage proteoglycans on hydroxyapatite growth

    • Chun-Chang Chen
    • Adele L. Boskey
    • Lawrence C. Rosenberg

    Laboratory Investigations Pages: 285 - 290

49. Failure to detect an amorphous calcium-phosphate solid phase in bone mineral: A radial distribution function study

    • Marc D. Grynpas
    • Laurence C. Bonar
    • Melvin J. Glimcher

    Laboratory Investigations Pages: 291 - 301

50. Fluoride absorption: The influence of gastric acidity

    • Gary M. Whitford
    • David H. Pashley

    Laboratory Investigations Pages: 302 - 307