Multi-omics profiling of CSF from spinal muscular atrophy type 3 patients after nusinersen treatment: a 2-year follow-up multicenter retrospective study Irene FaravelliDelia GagliardiLinda Ottoboni Original Article Open access 05 August 2023 Article: 241
Synergistic effects of hormones on structural and functional maturation of cardiomyocytes and implications for heart regeneration Anne-Marie GalowJulia BrenmoehlAndreas Hoeflich Review Open access 05 August 2023 Article: 240
The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies Roxanne Hsiang-Chi LiouShih-Wei ChenYu-Hui Wong Original Article Open access 04 August 2023 Article: 239
Soluble mutant huntingtin drives early human pathogenesis in Huntington’s disease Andrés MiguezCinta GomisJosep M. Canals Original Article Open access 03 August 2023 Article: 238
The expanding organelle lipidomes: current knowledge and challenges Maria J. SarmentoAlicia LlorenteMorana Jaganjac Review Open access 02 August 2023 Article: 237
An impaired splicing program underlies differentiation defects in hSOD1G93A neural progenitor cells Veronica VerdileVeronica RiccioniMaria Paola Paronetto Original Article 31 July 2023 Article: 236
Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis Sascha PustAndreas BrechKaisa Haglund Original Article Open access 31 July 2023 Article: 235
Proteolytic inactivation of CXCL12 in the lungs and circulation of COVID-19 patients Seppe CambierFabio BerettaPaul Proost Original Article 28 July 2023 Article: 234
Collagen VI sustains cell stemness and chemotherapy resistance in glioblastoma Matilde CesconElena RampazzoLuca Persano Original Article Open access 28 July 2023 Article: 233
BoGH13ASus from Bacteroides ovatus represents a novel α-amylase used for Bacteroides starch breakdown in the human gut Haley A. BrownAnna L. DeVeauxNicole M. Koropatkin Original Article 28 July 2023 Article: 232
The immunoproteasome subunit β2i ameliorates myocardial ischemia/reperfusion injury by regulating Parkin-Mfn1/2-mediated mitochondrial fusion Hui-Xiang SuPang-Bo LiHui-Hua Li Original Article 27 July 2023 Article: 231
Discovery of a selective NLRP3-targeting compound with therapeutic activity in MSU-induced peritonitis and DSS-induced acute intestinal inflammation Yinghua ZhouZhongjin YangPing Sun Original Article 27 July 2023 Article: 230
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells Yang BaiLong ZhangJinkun Wen Original Article Open access 27 July 2023 Article: 229
Integration of nuclear Ca2+ transients and subnuclear protein shuttling provides a novel mechanism for the regulation of CREB-dependent gene expression Anna KarpovaSebastian SamerMichael R. Kreutz Original Article Open access 25 July 2023 Article: 228
Development, circuitry, and function of the zebrafish cerebellum Sol Pose-MéndezPaul SchrammReinhard W. Köster Review Open access 25 July 2023 Article: 227
Restored UBE2C expression in islets promotes β-cell regeneration in mice by ubiquitinating PER1 Hemin JiangShuai ZhengQi Fu Original Article 24 July 2023 Article: 226
GSK-3β orchestrates the inhibitory innervation of adult-born dentate granule cells in vivo E. P. Moreno-JiménezM. Flor-GarcíaMaría Llorens-Martín Original Article Open access 23 July 2023 Article: 225
Transcriptomic landscape reveals germline potential of porcine skin-derived multipotent dermal fibroblast progenitors Wen-Xiang LiuChun-Xiao LiShun-Feng Cheng Original Article 22 July 2023 Article: 224
Kindlin-2 controls angiogenesis through modulating Notch1 signaling Yuechao DongGuixing MaHuiling Cao Original Article 22 July 2023 Article: 223
Single-cell multi-omics profiling reveals key regulatory mechanisms that poise germinal vesicle oocytes for maturation in pigs Xiaolong YuanNa ChenFei Gao Original Article 22 July 2023 Article: 222
Myeloid-derived suppressor cells impair CD4+ T cell responses during chronic Staphylococcus aureus infection via lactate metabolism Oliver GoldmannEva Medina Original Article Open access 22 July 2023 Article: 221
Genome editing and cancer therapy: handling the hypoxia-responsive pathway as a promising strategy Emanuela StamponeDebora BencivengaAdriana Borriello Review Open access 21 July 2023 Article: 220
Dietary restriction to optimize T cell immunity is an ancient survival strategy conserved in vertebrate evolution Kunming LiXiumei WeiJialong Yang Original Article 20 July 2023 Article: 219
WD repeat domain 82 (Wdr82) facilitates mouse iPSCs generation by interfering mitochondrial oxidative phosphorylation and glycolysis Guina CuiJingxuan ZhouKerong Shi Original Article Open access 20 July 2023 Article: 218
Pancreatic lipase-related protein 2 is selectively expressed by peritubular myoid cells in the murine testis and sustains long-term spermatogenesis Hai-Ping TaoTeng-Fei LuYun-Peng Hou Original Article 19 July 2023 Article: 217
Protrudin-mediated ER-endosome contact sites promote phagocytosis Liv Anker ElfmarkEva Maria WenzelCamilla Raiborg Original Article Open access 19 July 2023 Article: 216
VGLL4 promotes vascular endothelium specification via TEAD1 in the vascular organoids and human pluripotent stem cells-derived endothelium model Yingyi QuanMinjie HuYongyu Wang Original Article 19 July 2023 Article: 215
Comparative study of PRPH2 D2 loop mutants reveals divergent disease mechanism in rods and cones Larissa IkelleMustafa MakiaMuna I. Naash Original Article Open access 19 July 2023 Article: 214
DUSP1 interacts with and dephosphorylates VCP to improve mitochondrial quality control against endotoxemia-induced myocardial dysfunction Hang ZhuJin WangHao Zhou Original Article 18 July 2023 Article: 213
DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK1 − TRAF3 complex Yanwei ZhangJing CenJun Zou Original Article 18 July 2023 Article: 212
NUMA1 modulates apoptosis of esophageal squamous cell carcinoma cells through regulating ASK1-JNK signaling pathway Shuying YinSimin ZhaoZigang Dong Original Article 18 July 2023 Article: 211
Autophagy protein 5 controls flow-dependent endothelial functions Pierre NivoitThomas MathivetOlivia Lenoir Original Article Open access 18 July 2023 Article: 210
Dietary Na+ depletion up-regulates NKCC1 expression and enhances electrogenic Cl− secretion in rat proximal colon Andrew J. NickersonVazhaikkurichi M. Rajendran Original Article 17 July 2023 Article: 209
Correction: Persistence of FoxJ1+ Pax6+ Sox2+ ependymal cells throughout life in the human spinal cord Chantal RipollGaetan PoulenJean-Philippe Hugnot Correction 15 July 2023 Article: 208
Emerging roles of the cellular prion protein (PrPC) and 37/67 kDa laminin receptor (RPSA) interaction in cancer biology Adriana LimoneValentina MaggisanoStefania Bulotta Review Open access 15 July 2023 Article: 207
Intrapancreatic fat, pancreatitis, and pancreatic cancer Anna C. LillyIgor AstsaturovErica A. Golemis Review Open access 15 July 2023 Article: 206
EAT-2 attenuates C. elegans development via metabolic remodeling in a chemically defined food environment Xuwen CaoYusu XieLiusuo Zhang Original Article 14 July 2023 Article: 205
Correction: Overexpression of VIRMA confers vulnerability to breast cancers via the m6A-dependent regulation of unfolded protein response Quintin LeeRenhua SongJustin J.-L. Wong Correction Open access 14 July 2023 Article: 204
Catalytic antibodies in arrhythmogenic cardiomyopathy patients cleave desmoglein 2 and N-cadherin and impair cardiomyocyte cohesion Sunil YeruvaKonstanze StangnerJens Waschke Original Article Open access 14 July 2023 Article: 203
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways Claudia TitoIlaria GenoveseFrancesco Fazi Original Article Open access 13 July 2023 Article: 202
Correction: EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory Kathrin BarthVerica VasićMirko H. H. Schmidt Correction Open access 13 July 2023 Article: 201
Artificial induction of circadian rhythm by combining exogenous BMAL1 expression and polycomb repressive complex 2 inhibition in human induced pluripotent stem cells Hitomi KanekoTaku KaitsukaKazuhito Tomizawa Original Article 08 July 2023 Article: 200
Evolutionary shifts in pheromone receptors contribute to speciation in four Helicoverpa species Song CaoChen ShiGuirong Wang Original Article 08 July 2023 Article: 199
Looking outside the box: a comparative cross-kingdom view on the cell biology of the three major lineages of eukaryotic multicellular life Ralph PanstrugaWolfram AntoninAlexander Lichius Review Open access 07 July 2023 Article: 198
The emerging roles of long noncoding RNAs in lymphatic vascular development and disease Konstantin I. IvanovOlga V. SamuilovaAndrey A. Zamyatnin Jr. Review Open access 06 July 2023 Article: 197
Epigenetic silencing of OR and TAS2R genes expression in human orbitofrontal cortex at early stages of sporadic Alzheimer’s disease Victoria Cunha AlvesJoana Figueiro-SilvaEva Carro Original Article Open access 05 July 2023 Article: 196
