Altered thymocyte development observed in EphA4-deficient mice courses with changes in both thymic epithelial and extracellular matrix organization Javier García-CecaSara Montero-HerradónAgustín G. Zapata Original Article Open access 05 November 2022 Article: 583
Induction of pulmonary HLA-G expression by SARS-CoV-2 infection Barbara SeligerSimon Jasinski-BergnerMarcus Bauer Original Article Open access 05 November 2022 Article: 582
GLI1+ cells are a source of repair-supportive mesenchymal cells (RSMCs) during airway epithelial regeneration Xuran ChuArun LingampallyElie El Agha Original Article Open access 05 November 2022 Article: 581
SiHSFA2e regulated expression of SisHSP21.9 maintains chloroplast proteome integrity under high temperature stress Roshan Kumar SinghMehanathan MuthamilarasanManoj Prasad Original Article 03 November 2022 Article: 580
Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms Simon G. RoycePaul V. LicciardiTom C. Karagiannis Original Article 01 November 2022 Article: 579
Longitudinal metabolomic profiles reveal sex-specific adjustments to long-duration spaceflight and return to Earth Julia E. StroudMichael S. GaleGerlinde A. S. Metz Original Article 01 November 2022 Article: 578
Integrative insights and clinical applications of single-cell sequencing in cancer immunotherapy Zaoqu LiuHuanyun LiXinwei Han Review 31 October 2022 Article: 577
CD34+ cell atlas of main organs implicates its impact on fibrosis Xiangyuan PuPengwei ZhuHongkun Zhang Original Article 31 October 2022 Article: 576
Tubb3 expression levels are sensitive to neuronal activity changes and determine microtubule growth and kinesin-mediated transport Jennifer RadwitzTorben J. HausratMatthias Kneussel Original Article Open access 29 October 2022 Article: 575
Mitochondrial proteotoxicity: implications and ubiquitin-dependent quality control mechanisms Mariusz KarbowskiYumiko OshimaNicolas Verhoeven Review 29 October 2022 Article: 574
Mfn2-mediated mitochondrial fusion promotes autophagy and suppresses ovarian cancer progression by reducing ROS through AMPK/mTOR/ERK signaling Rahail AshrafSanjay Kumar Original Article 29 October 2022 Article: 573
Tumor-derived exosomal non-coding RNAs as diagnostic biomarkers in cancer Nasim EbrahimiFerdos FaghihkhorasaniAmir Reza Aref Review 29 October 2022 Article: 572
Structure and function of the N-terminal extension of the formin INF2 Leticia Labat-de-HozLaura ComasMiguel A. Alonso Original Article Open access 28 October 2022 Article: 571
Omics approach to reveal the effects of obesity on the protein profiles of the exosomes derived from different adipose depots Minting ChenFan ZhangHiu Yee Kwan Original Article 28 October 2022 Article: 570
Distinctive aspects of the placental epigenome and theories as to how they arise William A. PastorSin Young Kwon Review Open access 26 October 2022 Article: 569
Anthracycline-induced cardiotoxicity and cell senescence: new therapeutic option? Fernando A. C. SearaTais H. Kasai-BrunswickAntonio C. Campos-de-Carvalho Review 26 October 2022 Article: 568
Mycobacterium tuberculosis exploits MPT64 to generate myeloid-derived suppressor cells to evade the immune system Sanpreet SinghSudeep K. MauryaJaved N. Agrewala Original Article 25 October 2022 Article: 567
In human astrocytes neurotropic flaviviruses increase autophagy, yet their replication is autophagy-independent Petra Tavčar VerdevMaja PotokarJernej Jorgačevski Original Article Open access 25 October 2022 Article: 566
Basal Gp78-dependent mitophagy promotes mitochondrial health and limits mitochondrial ROS Parsa AlanKurt R. VandevoordeIvan R. Nabi Original Article Open access 25 October 2022 Article: 565
Cannabidiol as a modulator of α7 nicotinic receptors Juan Facundo ChrestiaMaría del Carmen EsandiCecilia Bouzat Original Article 25 October 2022 Article: 564
SLC6A14 facilitates epithelial cell ferroptosis via the C/EBPβ-PAK6 axis in ulcerative colitis Yanjun ChenWenying YanWeichang Chen Original Article 22 October 2022 Article: 563
Lost in promiscuity? An evolutionary and biochemical evaluation of HSD10 function in cardiolipin metabolism Yvonne WohlfarterReiner EidelpesMarkus A. Keller Original Article Open access 22 October 2022 Article: 562
Proteome alterations during clonal isolation of established human pancreatic cancer cell lines P. BernhardT. FeilenO. Schilling Original Article Open access 22 October 2022 Article: 561
Characterization of microtubule-associated protein tau isoforms and Alzheimer’s disease-like pathology in normal sheep (Ovis aries): relevance to their potential as a model of Alzheimer’s disease Emma S. DaviesRussell M. MorphewSebastian McBride Original Article Open access 21 October 2022 Article: 560
METTL3 modulates chromatin and transcription dynamics during cell fate transition Xiao-Min LiuYuanhui MaoShu-Bing Qian Original Article 20 October 2022 Article: 559
Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology Anika HeinzeCara SchuldtMarco B. Rust Original Article Open access 20 October 2022 Article: 558
Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA Miriam Morente-LópezRocío Mato-BasaloMaría C. Arufe Original Article Open access 20 October 2022 Article: 557
Arl13b controls basal cell stemness properties and Hedgehog signaling in the mouse epididymis Laura GirardetDaniel G. CyrClémence Belleannée Original Article 19 October 2022 Article: 556
The BACE1-generated C-terminal fragment of the neural cell adhesion molecule 2 (NCAM2) promotes BACE1 targeting to Rab11-positive endosomes Ryan KeableShangfeng HuVladimir Sytnyk Original Article Open access 17 October 2022 Article: 555
Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains Xingxing ChenYize SunShihua Li Original Article 17 October 2022 Article: 554
A plant-based mutant huntingtin model-driven discovery of impaired expression of GTPCH and DHFR Chiu-Yueh HungChuanshu ZhuJiahua Xie Original Article Open access 17 October 2022 Article: 553
L007-0069 kills Staphylococcus aureus in high resistant phenotypes She PengfeiLiu YaqianWu Yong Original Article 16 October 2022 Article: 552
Fluid shear stress promotes periodontal ligament cells proliferation via p38-AMOT-YAP Qiusheng ShiLisha ZhengYubo Fan Original Article 16 October 2022 Article: 551
Rewiring of the protein–protein–metabolite interactome during the diauxic shift in yeast Dennis SchlossarekMarcin LuzarowskiAleksandra Skirycz Original Article Open access 15 October 2022 Article: 550
Malaria parasites utilize two essential plasma membrane fusogens for gamete fertilization Sudhir KumarClari ValansiStefan H. I. Kappe Original Article 14 October 2022 Article: 549
HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress Joan Sala-GastonLeonardo PedrazzaJose Luis Rosa Original Article Open access 14 October 2022 Article: 548
Contribution of T- and B-cell intrinsic toll-like receptors to the adaptive immune response in viral infectious diseases Ejuan ZhangZhiyong MaMengji Lu Review Open access 12 October 2022 Article: 547
Integrin alpha9 emerges as a key therapeutic target to reduce metastasis in rhabdomyosarcoma and neuroblastoma Natalia NavarroCarla MolistJosep Roma Original Article Open access 11 October 2022 Article: 546
The left–right side-specific endocrine signaling in the effects of brain lesions: questioning of the neurological dogma Georgy Bakalkin Review Open access 11 October 2022 Article: 545
Human embryonic stem cell-specific role of YAP in maintenance of self-renewal and survival Mu Seog ChoeChang Min BaeMin Young Lee Original Article 11 October 2022 Article: 544
Role of sex hormone-binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology N. NarinxK. DavidD. Vanderschueren Review 07 October 2022 Article: 543
Phagocytosing differentiated cell-fragments is a novel mechanism for controlling somatic stem cell differentiation within a short time frame Shohei WakaoYo OgumaMari Dezawa Original Article Open access 06 October 2022 Article: 542
Postnatal deletion of Spns2 prevents neuroinflammation without compromising blood vascular functions Zafrul HasanToan Q. NguyenLong N. Nguyen Original Article 05 October 2022 Article: 541
Hetero-pentamerization determines mobility and conductance of Glycine receptor α3 splice variants Veerle LemmensBart TheveleinJelle Hendrix Original Article Open access 05 October 2022 Article: 540
Resveratrol in breast cancer treatment: from cellular effects to molecular mechanisms of action Mitra BehroozaghdamMaryam DehghaniAnupam Bishayee Review 04 October 2022 Article: 539
