1. Up front January 2016

   Up front 30 November 2015 Pages: 1 - 2

2. A new chapter

   • Sally M. Marshall

   Editorial 26 October 2015 Pages: 3 - 4

3. Maternal obesity legacy: exercise it away!

   • Petter S. Alm
   • Anna Krook
   • Thais de Castro Barbosa

   Commentary 21 October 2015 Pages: 5 - 8

   

4. Of mice (dogs) and men: getting to the heart of obesity-associated cardiac dysfunction

   • Christopher M. Haggerty
   • Linyuan Jing
   • Brandon K. Fornwalt

   Commentary 30 October 2015 Pages: 9 - 12

   

5. Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment

   • R. David Leslie
   • Jerry Palmer
   • Ake Lernmark

   Review 24 October 2015 Pages: 13 - 20

   

6. CTLA4-Ig in B7-1-positive diabetic and non-diabetic kidney disease

   • Roberto Bassi
   • Alessia Fornoni
   • Paolo Fiorina

   Review 26 September 2015 Pages: 21 - 29

   

7. Circulating leptin in non-alcoholic fatty liver disease: a systematic review and meta-analysis

   • Stergios A. Polyzos
   • Konstantinos N. Aronis
   • Christos S. Mantzoros

   Meta-Analysis 26 September 2015 Pages: 30 - 43

   

8. Role of insulin in the regulation of human skeletal muscle protein synthesis and breakdown: a systematic review and meta-analysis

   • Haitham Abdulla
   • Kenneth Smith
   • Iskandar Idris

   Meta-Analysis 24 September 2015 Pages: 44 - 55

   

9. High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: a randomised controlled trial

   • Sophie Cassidy
   • Christian Thoma
   • Michael I. Trenell

   Article Open access 09 September 2015 Pages: 56 - 66

   

10. The insulin resistance phenotype (muscle or liver) interacts with the type of diet to determine changes in disposition index after 2 years of intervention: the CORDIOPREV-DIAB randomised clinical trial

    • Ruth Blanco-Rojo
    • Juan F. Alcala-Diaz
    • Jose Lopez-Miranda

    Article 16 October 2015 Pages: 67 - 76

    

11. Resistance training improves skeletal muscle insulin sensitivity in elderly offspring of overweight and obese mothers

    • Marco Bucci
    • Ville Huovinen
    • Pirjo Nuutila

    Article 21 October 2015 Pages: 77 - 86

    

12. Use of insulin pump therapy in children and adolescents with type 1 diabetes and its impact on metabolic control: comparison of results from three large, transatlantic paediatric registries

    • Jennifer L. Sherr
    • Julia M. Hermann
    • for the T1D Exchange Clinic Network, the DPV Initiative, and the National Paediatric Diabetes Audit and the Royal College of Paediatrics and Child Health registries

    Short Communication 07 November 2015 Pages: 87 - 91

    

13. White’s classification and pregnancy outcome in women with type 1 diabetes: a population-based cohort study

    • Miira M. Klemetti
    • Hannele Laivuori
    • Kari Teramo

    Article 16 October 2015 Pages: 92 - 100

14. Long-term changes in sleep duration, energy balance and risk of type 2 diabetes

    • Elizabeth M. Cespedes
    • Shilpa N. Bhupathiraju
    • Frank B. Hu

    Article 02 November 2015 Pages: 101 - 109

    

15. Prospective associations between sedentary time, physical activity, fitness and cardiometabolic risk factors in people with type 2 diabetes

    • Maxine J. E. Lamb
    • Kate Westgate
    • on behalf of the ADDITION-Plus study team

    Article Open access 30 October 2015 Pages: 110 - 120

    

16. Substantial reduction in the number of amputations among patients with diabetes: a cohort study over 16 years

    • Benjamin S. B. Rasmussen
    • Knud B. Yderstraede
    • Henning Beck-Nielsen

    Article 22 November 2015 Pages: 121 - 129

    

17. Type 2 diabetes and leucocyte DNA methylation: an epigenome-wide association study in over 1,500 older adults

    • Ines Florath
    • Katja Butterbach
    • Hermann Brenner

    Article 03 October 2015 Pages: 130 - 138

    

18. Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice

    • Vivian Anastasiou
    • Elpiniki Ninou
    • Anthony Gavalas

    Article Open access 31 October 2015 Pages: 139 - 150

    

19. Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

    • Xiwen Xiong
    • Gaihong Wang
    • X. Charlie Dong

    Article 15 October 2015 Pages: 151 - 160

    

20. Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

    • Ksenia Tugay
    • Claudiane Guay
    • Romano Regazzi

    Article Open access 16 October 2015 Pages: 161 - 169

    

21. Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy

    • Cornelis R. van der Torren
    • Arnaud Zaldumbide
    • Bart O. Roep

    Short Communication Open access 21 October 2015 Pages: 170 - 175

    

22. Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle

    • Marco Ciccarelli
    • Viviana Vastolo
    • Paola Ungaro

    Article 09 October 2015 Pages: 176 - 186

    

23. JAK2 promotes brown adipose tissue function and is required for diet- and cold-induced thermogenesis in mice

    • Sally Yu Shi
    • Wei Zhang
    • Minna Woo

    Article 29 October 2015 Pages: 187 - 196

    

24. Rapid development of cardiac dysfunction in a canine model of insulin resistance and moderate obesity

    • Josiane L. Broussard
    • Michael D. Nelson
    • Richard N. Bergman

    Article 17 September 2015 Pages: 197 - 207

    

25. Death, end-stage renal disease and renal function decline in patients with diabetic nephropathy in French cohorts of type 1 and type 2 diabetes

    • Samy Hadjadj
    • Bertrand Cariou
    • on behalf of the French JDRF Diabetic Nephropathy Collaborative Research Initiative (search for genes determining time to onset of ESRD in T1D patients with proteinuria) and the SURDIAGENE and DIABHYCAR study groups

    Article 20 October 2015 Pages: 208 - 216

    

26. The influence of type 1 diabetes on pancreatic weight

    • Martha L. Campbell-Thompson
    • John S. Kaddis
    • Mark A. Atkinson

    Short Communication 10 September 2015 Pages: 217 - 221

    

27. Plasma fetuin-A does not correlate with monocyte TLR4 in humans

    • Ishwarlal Jialal
    • Sridevi Devaraj
    • Beverley Adams-Huet

    Letter 19 November 2015 Pages: 222 - 223