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Harnessing deep learning into hidden mutations of neurological disorders for therapeutic challenges Sumin YangSung-Hyun KimJae-Yeol Joo Review 01 June 2023 Pages: 535 - 549
Recent advances in GPR35 pharmacology; 5-HIAA serotonin metabolite becomes a ligand Dong-Soon Im Review 25 May 2023 Pages: 550 - 563
Effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of gliclazide in healthy subjects Pureum KangChang-Keun ChoJung-Woo Bae Research Article 25 April 2023 Pages: 438 - 447
Antibody drug conjugates as targeted cancer therapy: past development, present challenges and future opportunities Ritwik MaitiBhumika PatelNirav Dhanesha Review 18 April 2023 Pages: 361 - 388
Phytochemistry and pharmacology of natural prenylated flavonoids Hua-Wei LvQiao-Liang WangXing-Nuo Li Review 14 April 2023 Pages: 207 - 272
Aspergillus co-cultures: A recent insight into their secondary metabolites and microbial interactions Abdullah AlanziEsraa A. ElhawaryAshaimaa Y. Moussa Review 10 April 2023 Pages: 273 - 298
Metformin mitigates renal dysfunction in obese insulin-resistant rats via activation of the AMPK/PPARα pathway Laongdao ThongnakNattavadee PengrattanachotAnusorn Lungkaphin Research Article 26 March 2023 Pages: 408 - 422
The function, mechanisms, and clinical applications of metformin: potential drug, unlimited potentials Jianhong LiuMing ZhangXiao Zhu Review 24 March 2023 Pages: 389 - 407
Regulation of NOX/p38 MAPK/PPARα pathways and miR-155 expression by boswellic acids reduces hepatic injury in experimentally-induced alcoholic liver disease mouse model: novel mechanistic insight Rania M. SalamaSamah S. AbbasSara A. El Wakeel Research Article Open access 23 March 2023 Pages: 323 - 338
Low-dose curcumin enhances hippocampal neurogenesis and memory retention in young mice Yujeong LeeHee Ra ParkJaewon Lee Research Article 22 March 2023 Pages: 423 - 437
EGF, a veteran of wound healing: highlights on its mode of action, clinical applications with focus on wound treatment, and recent drug delivery strategies Kanchan ShakhakarmiJo-Eun SeoSangkil Lee Review 16 March 2023 Pages: 299 - 322
Apocynin abrogates methotrexate-induced nephrotoxicity: role of TLR4/NF-κB-p65/p38-MAPK, IL-6/STAT-3, PPAR-γ, and SIRT1/FOXO3 signaling pathways Emad H. M. HassaneinAhmed M. SayedFares E. M. Ali Research Article 13 March 2023 Pages: 339 - 359
Engineered fibrotic liver-targeted truncated transforming growth factor β receptor type II variant for superior anti-liver fibrosis therapy Manman MaXiaohua WangHaifeng Liu Research Article 11 March 2023 Pages: 177 - 191
Cathepsin B maturation plays a critical role in leptin-induced hepatic cancer cell growth through activation of NLRP3 inflammasomes ThiKem NguyenRaut Pawan KumarPil-Hoon Park Research Article 11 March 2023 Pages: 160 - 176
Anti-fibrotic effect of aurocyanide, the active metabolite of auranofin Hyun Young KimUndarmaa OtgontengerKeon Wook Kang Research Article 10 March 2023 Pages: 149 - 159
Correction to: The multifaceted role of STAT3 pathway and its implication as a potential therapeutic target in oral cancer Elina KhatoonMangala HegdeAjaikumar B. Kunnumakkara Correction 07 March 2023 Pages: 206 - 206
Antibody–drug conjugates and bispecific antibodies targeting cancers: applications of click chemistry Yeji HongSu-Min NamAree Moon Review 06 March 2023 Pages: 131 - 148
Naringin promotes fat browning mediated by UCP1 activation via the AMPK signaling pathway in 3T3-L1 adipocytes Ho Seon LeeChan Uk HeoChang-Ik Choi Research Article 25 February 2023 Pages: 192 - 205
Dapagliflozin attenuates myocardial remodeling in hypertension by activating the circadian rhythm signaling pathway Jing WangQiang SheJianlin Du Research Article 02 February 2023 Pages: 117 - 130
Tumor lactic acid: a potential target for cancer therapy Jun-Kyu Byun Review 02 February 2023 Pages: 90 - 110
Innate immune sensing of pathogens and its post-transcriptional regulations by RNA-binding proteins Ka Man TseOsamu Takeuchi Review 01 February 2023 Pages: 65 - 77
Distinctive role of inflammation in tissue repair and regeneration Bokeum ChoiChangjun LeeJe-Wook Yu Review 31 January 2023 Pages: 78 - 89
Isolation, structure elucidation, total synthesis, and biosynthesis of dermazolium A, an antibacterial imidazolium metabolite of a vaginal bacterium Dermabacter vaginalis Hye Ryeong KimJonghwan KimChung Sub Kim Research Article 16 January 2023 Pages: 35 - 43
The role and application of transcriptional repressors in cancer treatment Miso ParkKeon Wook KangJi Won Kim Review 16 January 2023 Pages: 1 - 17
MEKs/ERKs-mediated FBXO1/E2Fs interaction interference modulates G1/S cell cycle transition and cancer cell proliferation Ga-Eun LeeDohyun JeungYong-Yeon Cho Research Article 06 January 2023 Pages: 44 - 58
Recent advances in selective and targeted drug/gene delivery systems using cell-penetrating peptides So Hee NamJoonhyuck ParkHeebeom Koo Review 03 January 2023 Pages: 18 - 34
Effects of CYP2C19 genetic polymorphism on the pharmacokinetics of tolperisone in healthy subjects Chang‑Keun ChoJi-Young ByeonYun Jeong Lee Research Article 23 December 2022 Pages: 111 - 116
Effects of CYP2D6*10 allele on the pharmacokinetics of tolperisone Chang‑Keun ChoJi-Young ByeonYun Jeong Lee Research Article 21 December 2022 Pages: 59 - 64
Targeting cytokines and signaling molecules related to immune pathways in atopic dermatitis: therapeutic implications and challenges Hyung-Ook Kim Review 03 December 2022 Pages: 894 - 908
Non-alcoholic fatty liver disease and liver secretome Muhammad Sohaib KhanChoongho LeeSang Geon Kim Review 28 November 2022 Pages: 938 - 963
Neurological disorders of COVID-19: insights to applications of natural products from plants and microorganisms Faezeh AlmasiWen DangNing Li Review 28 November 2022 Pages: 909 - 937
Effects of phytoestrogens on reproductive organ health S. Swathi KrishnaBeena Briget KuriakoseP. K. Lakshmi Review 28 November 2022 Pages: 849 - 864
Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment Md. Emranul KarimSheikh Tanzina HaqueEzharul Hoque Chowdhury Review 24 November 2022 Pages: 865 - 893
6′-Sialylactose abolished lipopolysaccharide-induced inflammation and hyper-permeability in endothelial cells Dung Van NguyenThuy Le Lam NguyenKyung-Sun Heo Research Article 19 November 2022 Pages: 836 - 848
Comparative evaluation of bioactive phytochemicals in Spinacia oleracea cultivated under greenhouse and open field conditions Bum Soo LeeHae Min SoKi Hyun Kim Research Article 19 November 2022 Pages: 795 - 805
New tricyclic systems as photosensitizers towards triple negative breast cancer cells Marilia BarrecaAngela Maria IngarraAlessandra Montalbano Research Article Open access 18 November 2022 Pages: 806 - 821
Mouse models of nonalcoholic steatohepatitis and their application to new drug development Hieu Huy PhungChang Hoon Lee Review 01 November 2022 Pages: 761 - 794
Enhancement of S(+)-zaltoprofen oral bioavailability using nanostructured lipid carrier system Thi Mai Anh PhamDong Ho LeeCheong-Weon Cho Research Article 28 October 2022 Pages: 822 - 835
Inhibition of autophagy with chloroquine dysregulates mitochondrial quality control and energetics in adipocytes Hafiz Muhammad Ahmad JavaidHwayeon LimJoo Young Huh Research Article 28 October 2022 Pages: 731 - 742
Cardiotoxicity linked to anticancer agents and cardioprotective strategy Shraddha I. KhairnarYogesh A. KulkarniKavita Singh Review 28 October 2022 Pages: 704 - 730
Minor structural changes, major functional impacts: posttranslational modifications and drug targets Hyo Jung Kim Review 17 October 2022 Pages: 693 - 703
Enhanced bioavailability and hepatoprotective effect of silymarin by preparing silymarin-loaded solid dispersion formulation using freeze-drying method Dong Yu LimMinyeong PangIm-Sook Song Research Article 30 September 2022 Pages: 743 - 760
New insights into the role of the Golgi apparatus in the pathogenesis and therapeutics of human diseases Wooseon ChoiShinwon KangJiyoon Kim Review 30 September 2022 Pages: 671 - 692
Advanced therapeutic strategies targeting microglia: beyond neuroinflammation Min-Soo Kwon Review 27 September 2022 Pages: 618 - 630
Structures, biomimetic synthesis, and anti-SARS-CoV-2 activity of two pairs of enantiomeric phenylpropanoid-conjugated protoberberine alkaloids from the rhizomes of Corydalis decumbens Jing-Guang LuYingwei WangZhi-Hong Jiang Research Article 19 September 2022 Pages: 631 - 643
Inhibitory effects of 6′-sialyllactose on angiotensin II-induced proliferation, migration, and osteogenic switching in vascular smooth muscle cells Thuy Le Lam NguyenYujin JinKyung-Sun Heo Research Article 07 September 2022 Pages: 658 - 670
Caffeic acid phenethyl ester inhibits pseudo-allergic reactions via inhibition of MRGPRX2/MrgprB2-dependent mast cell degranulation Nisha AdhikariWon-Sik Shim Research Article 02 October 2022 Pages: 644 - 657
Physiologically based pharmacokinetic (PBPK) modeling of flurbiprofen in different CYP2C9 genotypes Sang-Sup WhangChang‑Keun ChoSeok-Yong Lee Research Article 26 August 2022 Pages: 584 - 595
Isoindolin-1-ones from the stems of Nicotiana tabacum and their antiviral activities Guang-Yu YangJia-Meng DaiQiu-Fen Hu Research Article 20 August 2022 Pages: 572 - 583