1. Editorial

   • Pietro Tiraboschi
   • Carlo Alberto De Fanti

   Editorial Pages: 3 - 5

2. The dementias

   • Bugiani O.

   Original Articles Pages: 7 - 8

3. The ethics of clinical research with cognitively impaired subjects

   • J. Harris

   Original Articles Pages: 9 - 13

4. Informed consent to clinical research

   • Santosuosso A.

   Original Articles Pages: 15 - 20

5. Standards of competence in demented people

   • Helmchen H.

   Original Articles Pages: 21 - 24

6. Disclosing the diagnosis to demented patients

   • Tiraboschi P.

   Original Articles Pages: 25 - 28

7. Advance directives for clinical research in dementia

   • Berghmans R. L. P.

   Original Articles Pages: 29 - 33

8. Informed consent, dementia and clinical research

   • Defanti C. A.

   Original Articles Pages: 35 - 42

9. Ethical and legal issues of clinical research involving the cognitively impaired: the role of institutional review boards in the U.S.

   • Siegler M.
   • Casarett D. J.

   Original Articles Pages: 43 - 47

10. Clinical research and dementia

    • Tognoni G.
    • Rivolta A. L.

    Original Articles Pages: 49 - 52

11. Ethical problems relating to clinical research involving demented subjects and ethics committees

    • Anzani A.
    • Franceschi M.

    Original Articles Pages: 53 - 56

12. Clinical research from the point of view of caregivers

    • Salvini Porro G.

    Original Articles Pages: 57 - 58