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The use of spacers (static and mobile) in infection knee arthroplasty

  • Revision Knee Arthroplasty (R Rossi, Section Editor)
  • Published:
Current Reviews in Musculoskeletal Medicine Aims and scope Submit manuscript

Abstract

Revision total knee arthroplasty (TKA) is the treatment of choice in patients with periprosthetic joint infection. It may be performed in either a single stage or two stages. In the latter option, between stages, an antibiotic-loaded spacer may be used to maintain a certain amount of joint stability and mobility after the infected implant is removed, adding an intra-articular concentration of antibiotics. There are two types of antibiotic-loaded cement spacers: static and dynamic. Static spacers basically create a temporary arthrodesis with antibiotic-loaded cement and usually are handmade within the surgical field. Dynamic spacers can be created intraoperatively by using different tools or may be prepackaged by the manufacturer; they allow range of motion between stages. In this article, the authors review the indications, surgical techniques, and results for static and dynamic spacers in two-stage revision TKA.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Parvizi J, Adeli B, Zmistowski B, Restrepo C, Greenwald AS. Management of periprosthetic joint infection: the current knowledge: AAOS exhibit selection. J Bone Joint Surg (Am Vol). 2012;94:e104.

    Google Scholar 

  2. Bozic KJ, Kurtz SM, Lau E, Ong K, Chiu V, Vail TP, et al. The epidemiology of revision total knee arthroplasty in the United States. Clin Orthop Relat Res. 2010;468:45–51.

    Article  PubMed Central  PubMed  Google Scholar 

  3. Parvizi J, Zmistowski B, Berbari EF, Bauer TW, Springer BD, Della Valle CJ, et al. New definition for periprosthetic joint infection: from the Workgroup of the Musculoskeletal Infection Society. Clin Orthop Relat Res. 2011;469:2992–4. This milestone paper defines the term periprosthetic joint infection.

    Article  PubMed Central  PubMed  Google Scholar 

  4. Workgroup Convened by the Musculoskeletal Infection S. New definition for periprosthetic joint infection. The Journal of arthroplasty. 2011;26:1136-8

  5. Della Valle C, Parvizi J, Bauer TW, DiCesare PE, Evans RP, Segreti J, et al. American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis of periprosthetic joint infections of the hip and knee. J Bone Joint Surg (Am Vol). 2011;93:1355–7.

    Article  Google Scholar 

  6. Lombardi Jr AV, Berend KR, Adams JB. Why knee replacements fail in 2013: patient, surgeon, or implant? J Bone Joint. 2014;96-B:101–4.

    Article  Google Scholar 

  7. Oduwole KO, Molony DC, Walls RJ, Bashir SP, Mulhall KJ. Increasing financial burden of revision total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2010;18:945–8.

    Article  PubMed  Google Scholar 

  8. Jamsen E, Stogiannidis I, Malmivaara A, Pajamaki J, Puolakka T, Konttinen YT. Outcome of prosthesis exchange for infected knee arthroplasty: the effect of treatment approach. Acta Orthop. 2009;80:67–77.

    Article  PubMed Central  PubMed  Google Scholar 

  9. Oussedik SI, Dodd MB, Haddad FS. Outcomes of revision total hip replacement for infection after grading according to a standard protocol. J Bone Joint Surg Br Vol. 2010;92:1222–6.

    Article  CAS  Google Scholar 

  10. Singer J, Merz A, Frommelt L, Fink B. High rate of infection control with one-stage revision of septic knee prostheses excluding MRSA and MRSE. Clin Orthop Relat Res. 2012;470:1461–71.

    Article  PubMed Central  PubMed  Google Scholar 

  11. Osmon DR, Berbari EF, Berendt AR, Lew D, Zimmerli W, Steckelberg JM, et al. Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2013;56:e1–25.

    Article  PubMed  Google Scholar 

  12. Dubee V, Zeller V, Lhotellier L, Kitzis MD, Ziza JM, Mamoudy P, et al. Continuous high-dose vancomycin combination therapy for methicillin-resistant staphylococcal prosthetic hip infection: a prospective cohort study. Clin Microbiol Infect. 2013;19:E98–105.

    Article  CAS  PubMed  Google Scholar 

  13. Esposito S, Esposito I, Leone S. Considerations of antibiotic therapy duration in community- and hospital-acquired bacterial infections. J Antimicrob Chemother. 2012;67:2570–5.

    Article  CAS  PubMed  Google Scholar 

  14. Bernard L, Legout L, Zurcher-Pfund L, Stern R, Rohner P, Peter R, et al. Six weeks of antibiotic treatment is sufficient following surgery for septic arthroplasty. J Infect. 2010;61:125–32.

    Article  PubMed  Google Scholar 

  15. Whittaker JP, Warren RE, Jones RS, Gregson PA. Is prolonged systemic antibiotic treatment essential in two-stage revision hip replacement for chronic Gram-positive infection? J Bone Joint Surg Br Vol. 2009;91:44–51.

    Article  CAS  Google Scholar 

  16. Cooper HJ, Della Valle CJ. The two-stage standard in revision total hip replacement. J Bone Joint. 2013;95-B:84–7.

    Article  CAS  Google Scholar 

  17. Masters JP, Smith NA, Foguet P, Reed M, Parsons H, Sprowson AP. A systematic review of the evidence for single stage and two stage revision of infected knee replacement. BMC Musculoskelet Disord. 2013;14:222.

    Article  PubMed Central  PubMed  Google Scholar 

  18. Romanò CL, Gala L, Logoluso N, Romanò D, Drago L. Two-stage revision of septic knee prosthesis with articulating knee spacers yields better infection eradication rate than one-stage or two-stage revision with static spacers. Knee Surg Sports Traumatol Arthrosc. 2012;20:2445–53.

    Article  PubMed  Google Scholar 

  19. Tigani D, Trisolino G, Fosco M, Ben Ayad R, Costigliola P. Two-stage reimplantation for periprosthetic knee infection: Influence of host health status and infecting microorganism. Knee. 2013;20:9–18.

    Article  CAS  PubMed  Google Scholar 

  20. Stammers J, Kahane S, Ranawat V, Miles J, Pollock R, Carrington RW, et al. Outcomes of infected revision knee arthroplasty managed by two-stage revision in a tertiary referral centre. Knee. 2015;22:56–62.

    Article  PubMed  Google Scholar 

  21. Iarikov D, Demian H, Rubin D, Alexander J, Nambiar S. Choice and doses of antibacterial agents for cement spacers in treatment of prosthetic joint infections: review of published studies. Clin Infect Dis. 2012;55:1474–80.

    Article  CAS  PubMed  Google Scholar 

  22. Antoci V, Phillips MJ, Antoci Jr V, Krackow KA. The treatment of recurrent chronic infected knee arthroplasty with a 2-stage procedure. J Arthroplast. 2009;24(159):e13–7.

    Google Scholar 

  23. Jacobs C, Christensen CP, Berend ME. Static and mobile antibiotic-impregnated cement spacers for the management of prosthetic joint infection. J Am Acad Orthop Surg. 2009;17:356–68.

    PubMed  Google Scholar 

  24. Incavo SJ, Russell RD, Mathis KB, Adams H. Initial results of managing severe bone loss in infected total joint arthroplasty using customized articulating spacers. J Arthroplast. 2009;24:607–13.

    Article  Google Scholar 

  25. Faschingbauer M, Bieger R, Reichel H, Weiner C, Kappe T. Complications associated with 133 static, antibiotic-laden spacers after TKA. Knee Surg, Sports Traumatol Arthrosc 2015.

  26. Antoci V, Phillips MJ, Antoci Jr V, Krackow KA. Using an antibiotic-impregnated cement rod-spacer in the treatment of infected total knee arthroplasty. Am J Orthop. 2009;38:31–3.

    PubMed  Google Scholar 

  27. Hofmann AA, Goldberg T, Tanner AM, Kurtin SM. Treatment of infected total knee arthroplasty using an articulating spacer: 2- to 12-year experience. Clin Orthop Relat Res. 2005;430:125–31.

    Article  PubMed  Google Scholar 

  28. Park SJ, Song EK, Seon JK, Yoon TR, Park GH. Comparison of static and mobile antibiotic-impregnated cement spacers for the treatment of infected total knee arthroplasty. Int Orthop. 2010;34:1181–6.

    Article  PubMed Central  PubMed  Google Scholar 

  29. Shen H, Zhang X, Jiang Y, Wang Q, Chen Y, Wang Q, et al. Intraoperatively-made cement-on-cement antibiotic-loaded articulating spacer for infected total knee arthroplasty. Knee. 2010;17:407–11.

    Article  PubMed  Google Scholar 

  30. Voleti PB, Baldwin KD, Lee GC. Use of static or articulating spacers for infection following total knee arthroplasty: a systematic literature review. J Bone Joint Surg Am Vol. 2013;95:1594–9.

    Article  Google Scholar 

  31. Kotwal SY, Farid YR, Patil SS, Alden KJ, Finn HA. Intramedullary rod and cement static spacer construct in chronically infected total knee arthroplasty. J Arthroplast. 2012;27:253–9. e4.

    Article  Google Scholar 

  32. Macmull S, Bartlett W, Miles J, Blunn GW, Pollock RC, Carrington RW, et al. Custom-made hinged spacers in revision knee surgery for patients with infection, bone loss and instability. Knee. 2010;17:403–6.

    Article  CAS  PubMed  Google Scholar 

  33. Silvestre A, Almeida F, Renovell P, Morante E, Lopez R. Revision of infected total knee arthroplasty: two-stage reimplantation using an antibiotic-impregnated static spacer. Clin Orthop Surg. 2013;5:180–7.

    Article  PubMed Central  PubMed  Google Scholar 

  34. Aggarwal VK, Higuera C, Deirmengian G, Parvizi J, Austin MS. Swab cultures are not as effective as tissue cultures for diagnosis of periprosthetic joint infection. Clin Orthop Relat Res. 2013;471:3196–203.

    Article  PubMed Central  PubMed  Google Scholar 

  35. Atkins BL, Athanasou N, Deeks JJ, Crook DW, Simpson H, Peto TE, et al. Prospective evaluation of criteria for microbiological diagnosis of prosthetic-joint infection at revision arthroplasty. The OSIRIS Collaborative Study Group. J Clin Microbiol. 1998;36:2932–9.

    PubMed Central  CAS  PubMed  Google Scholar 

  36. Zappe B, Graf S, Ochsner PE, Zimmerli W, Sendi P. Propionibacterium spp. in prosthetic joint infections: a diagnostic challenge. Arch Orthop Trauma Surg. 2008;128:1039–46.

    Article  PubMed  Google Scholar 

  37. Burnett RS, Kelly MA, Hanssen AD, Barrack RL. Technique and timing of two-stage exchange for infection in TKA. Clin Orthop Relat Res. 2007;464:164–78.

    PubMed  Google Scholar 

  38. Paz E, Sanz-Ruiz P, Abenojar J, Vaquero-Martin J, Forriol F, Del Real JC. Evaluation of elution and mechanical properties of high-dose antibiotic-loaded bone cement: comparative “in vitro” study of the influence of vancomycin and cefazolin. J Arthroplast. 2015;30:1423–9.

    Article  Google Scholar 

  39. Hsu YC, Cheng HC, Ng TP, Chiu KY. Antibiotic-loaded cement articulating spacer for 2-stage reimplantation in infected total knee arthroplasty: a simple and economic method. J Arthroplast. 2007;22:1060–6.

    Article  CAS  Google Scholar 

  40. Choi HR, Malchau H, Bedair H. Are prosthetic spacers safe to use in 2-stage treatment for infected total knee arthroplasty? J Arthroplast. 2012;27:1474–9. e1.

    Article  Google Scholar 

  41. Thabe H, Schill S. Two-stage reimplantation with an application spacer and combined with delivery of antibiotics in the management of prosthetic joint infection. Oper Orthop Traumatol. 2007;19:78–100.

    Article  PubMed  Google Scholar 

  42. Cai P, Hu Y, Xie L, Wang L. Two-stage revision of infected total knee arthroplasty using antibiotic-impregnated articulating cement spacer. zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2012;26:1169–73.

    PubMed  Google Scholar 

  43. Garg P, Ranjan R, Bandyopadhyay U, Chouksey S, Mitra S, Gupta SK. Antibiotic-impregnated articulating cement spacer for infected total knee arthroplasty. Indian J Orthop. 2011;45:535–40.

    Article  PubMed Central  PubMed  Google Scholar 

  44. Pitto RP, Castelli CC, Ferrari R, Munro J. Pre-formed articulating knee spacer in two-stage revision for the infected total knee arthroplasty. Int Orthop. 2005;29:305–8.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  45. Wan Z, Karim A, Momaya A, Incavo SJ, Mathis KB. Preformed articulating knee spacers in 2-stage total knee revision arthroplasty: minimum 2-year follow-up. J Arthroplast. 2012;27:1469–73.

    Article  Google Scholar 

  46. Durbhakula SM, Czajka J, Fuchs MD, Uhl RL. Antibiotic-loaded articulating cement spacer in the 2-stage exchange of infected total knee arthroplasty. J Arthroplast. 2004;19:768–74.

    Article  Google Scholar 

  47. Villanueva M, Rios A, Pereiro J, Chana F, Fahandez-Saddi H. Hand-made articulating spacers for infected total knee arthroplasty: a technical note. Acta Orthop. 2006;77:329–32.

    Article  PubMed  Google Scholar 

  48. Hanssen AD, Spangehl MJ. Practical applications of antibiotic-loaded bone cement for treatment of infected joint replacements. Clin Orthop Relat Res. 2004;427:79–85. This article presents good clinical guidelines for application of antibiotic-loaded cemented spacers.

    Article  PubMed  Google Scholar 

  49. Johnson AJ, Sayeed SA, Naziri Q, Khanuja HS, Mont MA. Minimizing dynamic knee spacer complications in infected revision arthroplasty. Clin Orthop Relat Res. 2012;470:220–7.

    Article  PubMed Central  PubMed  Google Scholar 

  50. Hofmann AA, Kane KR, Tkach TK, Plaster RL, Camargo MP. Treatment of infected total knee arthroplasty using an articulating spacer. Clin Orthop Relat Res. 1995;321:45–54.

    PubMed  Google Scholar 

  51. Gooding CR, Masri BA, Duncan CP, Greidanus NV, Garbuz DS. Durable infection control and function with the PROSTALAC spacer in two-stage revision for infected knee arthroplasty. Clin Orthop Relat Res. 2011;469:985–93.

    Article  PubMed Central  PubMed  Google Scholar 

  52. Haddad FS, Masri BA, Campbell D, McGraw RW, Beauchamp CP, Duncan CP. The PROSTALAC functional spacer in two-stage revision for infected knee replacements. Prosthesis of antibiotic-loaded acrylic cement. J Bone Joint Surg Br Vol. 2000;82:807–12.

    Article  CAS  Google Scholar 

  53. Wang CJ, Hsieh MC, Huang TW, Wang JW, Chen HS, Liu CY. Clinical outcome and patient satisfaction in aseptic and septic revision total knee arthroplasty. Knee. 2004;11:45–9.

    Article  PubMed  Google Scholar 

  54. Pivec R, Naziri Q, Issa K, Banerjee S, Mont MA. Systematic review comparing static and articulating spacers used for revision of infected total knee arthroplasty. J Arthroplast. 2014;29:553–7. e1.

    Article  Google Scholar 

  55. Guild 3rd GN, Wu B, Scuderi GR. Articulating vs. static antibiotic impregnated spacers in revision total knee arthroplasty for sepsis. A systematic review. J Arthroplast. 2014;29:558–63.

    Article  Google Scholar 

  56. Parvizi J, Gehrke T, Chen AF. Proceedings of the international consensus on periprosthetic joint infection. J Bone Joint. 2013;95-B:1450–2. This article presents some of the most important guidelines on which current practice is based.

    Article  CAS  Google Scholar 

  57. Anderson JA, Sculco PK, Heitkemper S, Mayman DJ, Bostrom MP, Sculco TP. An articulating spacer to treat and mobilize patients with infected total knee arthroplasty. J Arthroplasty. 2009;24:631–5.

    Article  PubMed  Google Scholar 

  58. Chiang ER, Su YP, Chen TH, Chiu FY, Chen WM. Comparison of articulating and static spacers regarding infection with resistant organisms in total knee arthroplasty. Acta Orthop. 2011;82:460–4.

    Article  PubMed Central  PubMed  Google Scholar 

  59. Cuckler JM. The infected total knee: management options. J Arthroplasty. 2005;20:33–6.

    Article  PubMed  Google Scholar 

  60. Emerson Jr RH, Muncie M, Tarbox TR, Higgins LL. Comparison of a static with a mobile spacer in total knee infection. Clin Orthop Relat Res. 2002;404:132–8.

    Article  PubMed  Google Scholar 

  61. Evans RP. Successful treatment of total hip and knee infection with articulating antibiotic components: a modified treatment method. Clin Orthop Relat Res. 2004;427:37–46.

    Article  PubMed  Google Scholar 

  62. Fehring TK, Odum S, Calton TF, Mason JB. Articulating versus static spacers in revision total knee arthroplasty for sepsis. The Ranawat Award. Clin Orthop Relat Res. 2000;380:9–16.

    Article  PubMed  Google Scholar 

  63. Freeman MG, Fehring TK, Odum SM, Fehring K, Griffin WL, Mason JB. Functional advantage of articulating versus static spacers in 2-stage revision for total knee arthroplasty infection. J Arthroplasty. 2007;22:1116–21.

    Article  PubMed  Google Scholar 

  64. Haleem AA, Berry DJ, Hanssen AD. Mid-term to long-term followup of two-stage reimplantation for infected total knee arthroplasty. Clin Orthop Relat Res. 2004;428:35–9.

    Article  PubMed  Google Scholar 

  65. Hart WJ, Jones RS. Two-stage revision of infected total knee replacements using articulating cement spacers and short-term antibiotic therapy. J Bone Joint Surg (Br). 2006;88:1011–5.

    Article  CAS  Google Scholar 

  66. Hoad-Reddick DA, Evans CR, Norman P, Stockley I. Is there a role for extended antibiotic therapy in a two-stage revision of the infected knee arthroplasty? J Bone Joint Surg (Br). 2005;87:171–4.

    Article  CAS  Google Scholar 

  67. Hsu CS, Hsu CC, Wang JW, Lin PC. Two-stage revision of infected total knee arthroplasty using an antibiotic-impregnated static cement-spacer. Chang Gung Med J. 2008;31:583–91.

    PubMed  Google Scholar 

  68. Huang HT, Su JY, Chen SK. The results of articulating spacer technique for infected total knee arthroplasty. J Arthroplasty. 2006;21:1163–8.

    Article  PubMed  Google Scholar 

  69. Hwang BH, Yoon JY, Nam CH, Jung KA, Lee SC, Han CD, et al. Fungal peri-prosthetic joint infection after primary total knee replacement. J Bone Joint Surg (Br). 2012;94:656–9.

    Article  CAS  Google Scholar 

  70. Jaekel DJ, Day JS, Klein GR, Levine H, Parvizi J, Kurtz SM. Do dynamic cement-on-cement knee spacers provide better function and activity during two-stage exchange? Clin Orthop Relat Res. 2012;470:2599–604.

    Article  PubMed Central  PubMed  Google Scholar 

  71. Jämsen E, Sheng P, Halonen P, Lehto MU, Moilanen T, Pajamäki J, et al. Spacer prostheses in two-stage revision of infected knee arthroplasty. Int Orthop. 2006;30:257–61.

    Article  PubMed Central  PubMed  Google Scholar 

  72. Jia YT, Zhang Y, Ding C, Zhang N, Zhang DL, Sun ZH, et al. Antibiotic-loaded articulating cement spacers in two-stage revision for infected total knee arthroplasty: individual antibiotic treatment and early results of 21 cases. Chin J Traumatol. 2012;15:212–21.

    CAS  PubMed  Google Scholar 

  73. Kalore NV, Maheshwari A, Sharma A, Cheng E, Gioe TJ. Is there a preferred articulating spacer technique for infected knee arthroplasty? A preliminary study. Clin Orthop Relat Res. 2012;470:228–35.

    Article  PubMed Central  PubMed  Google Scholar 

  74. Kohl S, Evangelopoulos DS, Kohlhof H, Krueger A, Hartel M, Roeder C, et al. An intraoperatively moulded PMMA prostheses like spacer for two-stage revision of infected total knee arthroplasty. Knee. 2011;18:464–9.

    Article  PubMed  Google Scholar 

  75. Lee JK, Choi CH. Two-stage reimplantation in infected total knee arthroplasty using a re-sterilized tibial polyethylene insert and femoral component. J Arthroplasty. 2012;27:1701–6.

    Article  PubMed  Google Scholar 

  76. MacAvoy MC, Ries MD. The ball and socket articulating spacer for infected total knee arthroplasty. J Arthroplasty. 2005;20:757–62.

    Article  PubMed  Google Scholar 

  77. Macheras GA, Kateros K, Galanakos SP, Koutsostathis SD, Kontou E, Papadakis SA. The long-term results of a two-stage protocol for revision of an infected total knee replacement. J Bone Joint Surg (Br). 2011;93:1487–92.

    Article  CAS  Google Scholar 

  78. Meek RM, Dunlop D, Garbuz DS, McGraw R, Greidanus NV, Masri BA. Patient satisfaction and functional status after aseptic versus septic revision total knee arthroplasty using the PROSTALAC articulating spacer. J Arthroplasty. 2004;19:874–9.

    Article  PubMed  Google Scholar 

  79. Ocguder A, Firat A, Tecimel O, Solak S, Bozkurt M. Two-stage total infected knee arthroplasty treatment with articulating cement spacer. Arch Orthop Trauma Surg. 2010;130:719–25.

    Article  PubMed  Google Scholar 

  80. Pascale V, Pascale W. Custom-made articulating spacer in two-stage revision total knee arthroplasty. An early follow-up of 14 cases of at least 1 year after surgery. HSS J. 2007;3:159–63.

    Article  PubMed Central  PubMed  Google Scholar 

  81. Pietsch M, Hofmann S, Wenisch C. Treatment of deep infection of total knee arthroplasty using a two-stage procedure. Oper Orthop Traumatol. 2006;18:66–87.

    Article  PubMed  Google Scholar 

  82. Qiu XS, Sun X, Chen DY, Xu ZH, Jiang Q. Application of an articulating spacer in two-stage revision for severe infection after total knee arthroplasty. Orthop Surg. 2010;2:299–304.

    Article  PubMed  Google Scholar 

  83. Shaikh AA, Ha CW, Park YG, Park YB. Two-stage approach to primary TKA in infected arthritic knees using intraoperatively molded articulating cement spacers. Clin Orthop Relat Res. 2014;472:2201–7.

    Article  PubMed Central  PubMed  Google Scholar 

  84. Siebel T, Kelm J, Porsch M, Regitz T, Neumann WH. Two-stage exchange of infected knee arthroplasty with an prosthesis-like interim cement spacer. Acta Orthop Belg. 2002;68:150–6.

    CAS  PubMed  Google Scholar 

  85. Souillac V, Costes S, Aunoble S, Langlois V, Dutronc H, Chauveaux D. Evaluation of an articulated spacer for two-stage reimplantation for infected total knee arthroplasty: 28 cases. Rev Chir Orthop Reparatrice Appar Mot. 2006;92:485–9.

    Article  CAS  PubMed  Google Scholar 

  86. Su YP, Lee OK, Chen WM, Chen TH. A facile technique to make articulating spacers for infected total knee arthroplasty. J Chin Med Assoc. 2009;72:138–45.

    Article  PubMed  Google Scholar 

  87. Van Thiel GS, Berend KR, Klein GR, Gordon AC, Lombardi AV, Della Valle CJ. Intraoperative molds to create an articulating spacer for the infected knee arthroplasty. Clin Orthop Relat Res. 2011;469:994–1001.

    Article  PubMed Central  PubMed  Google Scholar 

  88. Trezies A, Parish E, Dixon P, Cross M. The use of an articulating spacer in the management of infected total knee arthroplasties. J Arthroplasty. 2006;21:702–4.

    Article  PubMed  Google Scholar 

  89. Villanueva-Martínez M, Ríos-Luna A, Pereiro J, Fahandez-Saddi H, Villamor A. Hand-made articulating spacers in two-stage revision for infected total knee arthroplasty: good outcome in 30 patients. Acta Orthop. 2008;79:674–82.

    Article  PubMed  Google Scholar 

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  1. Department of Orthopedic Surgery, Osp. Mauriziano, Largo Turati, 62, Torino, 10100, Italy

    Luca Mazzucchelli, Federica Rosso, Antongiulio Marmotti, Davide Edoardo Bonasia, Matteo Bruzzone & Roberto Rossi

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  1. Luca Mazzucchelli
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  2. Federica Rosso
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  3. Antongiulio Marmotti
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  4. Davide Edoardo Bonasia
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Correspondence to Roberto Rossi.

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This article is part of the Topical Collection on Revision Knee Arthroplasty

Investigation was performed at the Hospital Mauriziano “Umberto I”, Torino, Italy.

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Mazzucchelli, L., Rosso, F., Marmotti, A. et al. The use of spacers (static and mobile) in infection knee arthroplasty. Curr Rev Musculoskelet Med 8, 373–382 (2015). https://doi.org/10.1007/s12178-015-9293-8

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