Skip to main content

Advertisement

SpringerLink
Log in

Clinical epidemiology for childhood primary central nervous system tumors

  • Clinical Study - Patient Study
  • Published:
Journal of Neuro-Oncology Aims and scope Submit manuscript

Abstract

This work was conducted by the French Brain Tumor Data Bank (FBTDB) and aims to prospectively record all primary central nervous system tumors (PCNST), in France, for which histological diagnosis is available. Results concerning children are presented. This study analyzes the childhood cases (0–19 years) of newly diagnosed and histologically confirmed PCNST (during the years 2004–2006) which have been recorded by the FBTDB. All French neuropathology and neurosurgery departments participated in this program. Neurosurgeons and neuropathologists completed a data file containing socio-demographic, clinical, radiologic and anatomopathologic information. The Tumor Registry from Herault was authorized to compile the data files with personal identifiers. About 1,017 cases (533 boys and 484 girls) of newly diagnosed childhood PCNST have been recorded (gliomas: 52%, all other neuroepithelial tumors: 31%, craniopharyngioma: 5%, germ cell tumors, meningioma and neurinoma: approximately 3% each, all histological subtypes have been detailed). Tumor resections were performed in 83.3%, and biopsies in 16.7%. The distributions by histology, cryopreservation of the samples, age, sex, tumor site and surgery have been detailed. To our knowledge, this work is the first databank in Europe dedicated to PCNST that includes the collection of clinical, radiological and histological data (including cryopreservation of the specimen). The long term goals of the FBTDB are to create a national registry and a network to perform epidemiological studies, to implement clinical and basic research protocols, and to evaluate and harmonize the healthcare of children and adult patients affected by PCNST.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Davis FG, Bruner JM, Surawicz TS (1997) The rationale for standardized registration and reporting of brain and central nervous system tumors in population-based cancer registries. Neuroepidemiology 16:308–316. doi:10.1159/000109703

    Article  PubMed  CAS  Google Scholar 

  2. Kleihues P, Cavenee WK (2000) World health classification of tumors. Tumors of the nervous system. Pathology and genetics. IARC Scientific Publications, Lyon

    Google Scholar 

  3. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P (2007) The 2007 WHO classification of tumors of the central nervous system. Acta Neuropathol 114:97–109. doi:10.1007/s00401-007-0243-4

    Article  PubMed  Google Scholar 

  4. McCarthy BJ, Surawicz T, Bruner JM, Kruchko C, Davis F (2002) Consensus conference on brain tumor definition for registration. Neuro-oncol 4:134–145. doi:10.1215/15228517-4-2-134

    Article  PubMed  Google Scholar 

  5. McCarthy BJ, Kruchko C, Central Brain Tumor Registry of United States (2005) Consensus conference on cancer registration of brain and central nervous system tumors. Neuro-oncol 7:196–201. doi:10.1215/S115285170400050X

    Article  PubMed  Google Scholar 

  6. Wrensch M, Minn Y, Chew T, Bondy M, Berger MS (2002) Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro-oncol 4:278–299. doi:10.1215/15228517-4-4-278

    Article  PubMed  Google Scholar 

  7. Baldwin RT, Preston-Martin S (2004) Epidemiology of brain tumors in childhood—a review. Toxicol Appl Pharmacol 199:118–131. doi:10.1016/j.taap.2003.12.029

    Article  PubMed  CAS  Google Scholar 

  8. Gurney JG, Smith MA, Bunin GR (1999) CNS and miscellaneous intra-cranial and intraspinal neoplasms. In: Ries LAG, Smith MA, Gurney JG, et al (eds) Cancer incidence and survival among children and adolescents: United States SEER Program 1975–1995. National Cancer Institute, SEER Program. NIH Pub No 99–4649. Bethesda, MD. Available at http://seer.cancer.gov/publications

  9. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ (2007) Cancer statistics, 2007. CA Cancer J Clin 57:43–66

    Article  PubMed  Google Scholar 

  10. CBTRUS Central Brain Tumor Registry of the United States (2008) Statistical Report 2000–2004 and Statistical Report Supplement 2004. Available at http://www.cbtrus.org

  11. Cho KT, Wang KC, Kim SK, Shin SH, Chi JG, Cho BK (2002) Pediatric brain tumors: statistics of SNUH, Korea (1959–2000). Childs Nerv Syst 18:30–37. doi:10.1007/s00381-001-0547-y

    Article  PubMed  Google Scholar 

  12. Gjerris F, Agerlin N, Børgesen SE, Buhl L, Haase J, Klinken L, Mortensen AC, Olsen JH, Ovesen N, Reske-Nielsen E, Schmidt K (1998) Epidemiology and prognosis in children treated for intracranial tumors in Denmark 1960–1984. Childs Nerv Syst 14:302–311. doi:10.1007/s003810050231

    Article  PubMed  CAS  Google Scholar 

  13. Kaatsch P, Rickert CH, Kuhl J, Schuz J, Michaelis J (2001) Population-based epidemiologic data on brain tumors in German children. Cancer 92:3155–3164. doi:10.1002/1097-0142(20011215)92:12<3155::AID-CNCR10158>3.0.CO;2-C

    Article  PubMed  CAS  Google Scholar 

  14. Keene DL, Hsu E, Ventureyra E (1999) Brain tumors in childhood and adolescence. Pediatr Neurol 20:198–203. doi:10.1016/S0887-8994(98)00139-8

    Article  PubMed  CAS  Google Scholar 

  15. Linabery AM, Ross JA (2008) Trends in childhood cancer incidence in the U.S. (1992–2004). Cancer 112:416–432. doi:10.1002/cncr.23169

    Article  PubMed  Google Scholar 

  16. Mehrazin M, Yavari P (2007) Morphological pattern and frequency of intracranial tumors in children. Childs Nerv Syst 23:157–162. doi:10.1007/s00381-006-0198-0

    Article  PubMed  CAS  Google Scholar 

  17. Rosemberg S, Fujiwara D (2005) Epidemiology of pediatric tumors of the nervous system according to the WHO 2000 classification: a report of 1, 195 cases from a single institution. Childs Nerv Syst 21:940–944. doi:10.1007/s00381-005-1181-x

    Article  PubMed  Google Scholar 

  18. Wong TT, Ho DM, Chang KP, Yen SH, Guo WY, Chang FC, Liang ML, Pan HC, Chung WY (2005) Primary pediatric brain tumors: statistics of Taipei VGH, Taiwan (1975–2004). Cancer 104:2156–2167. doi:10.1002/cncr.21430

    Article  PubMed  Google Scholar 

  19. Peris-Bonet R, Martínez-García C, Lacour B, Petrovich S, Giner-Ripoll B, Navajas A, Steliarova-Foucher E (2006) Childhood central nervous system tumors–incidence and survival in Europe (1978–1997): report from Automated Childhood Cancer Information System project. Eur J Cancer 42:2064–2080. doi:10.1016/j.ejca.2006.05.009

    Article  PubMed  Google Scholar 

  20. Berger C, Trombert-Paviot B, Mitton N, Frappaz D, Galambrun C, Plantaz D, Dupuis S, Bertrand Y, Philippe N, Schell M, Marec-Bérard P, Bergeron C, Armari-Alla C, Pagnier A, Stephan JL, Freycon F (2006) Childhood cancer incidence and survival rates in the Rhône–Alpes regional paediatric registry 1987–1999. Arch Pediatr 13:121–129. doi:10.1016/j.arcped.2005.10.022

    Article  PubMed  CAS  Google Scholar 

  21. Desandes E, Clavel J, Berger C, Bernard JL, Blouin P, de Lumley L, Demeocq F, Freycon F, Gembara P, Goubin A, Le Gall E, Pillon P, Sommelet D, Tron I, Lacour B (2004) Cancer incidence among children in France, 1990–1999. Pediatr Blood Cancer 43:749–757. doi:10.1002/pbc.20148

    Article  PubMed  Google Scholar 

  22. Lacour B, Desandes E, Mallol N, Sommelet D (2005) Lorraine childhood cancer registry: incidence, survival 1983–1999. Arch Pediatr 12:1577–1586. doi:10.1016/j.arcped.2005.06.010

    Article  PubMed  CAS  Google Scholar 

  23. RNTSE Registre National des Tumeurs Solides de l’Enfant (2006) Available at www.chu-nancy.fr/rntse. Accessed September 2006

  24. Bauchet L, Rigau V, Mathieu-Daudé H, Figarella-Branger D, Hugues D, Palusseau L, Bauchet F, Fabbro M, Campello C, Capelle L, Durand A, Trétarre B, Frappaz D, Henin D, Menei P, Honnorat J, Segnarbieux F (2007) French brain tumor data bank: methodology and first results on 10,000 cases. J Neurooncol 84:189–199. doi:10.1007/s11060-007-9356-9

    Article  PubMed  Google Scholar 

  25. ADICAP Association pour le Développement de l’Informatique en Cytologie et en Anatomie Pathologiques (2003) Database online. Edition 2003-Version 5-2003.pdf-Copyright ADICAP. Available at http://www.adicap.asso.fr/thesaurus/Adicap_v5-03.pdf. Accessed 2003

  26. Bauchet L, Capelle L, Stilhart B, Guyotat J, Pinelli C, Roches P, Barat JL, Loiseau H, Wager M, Gay E, Garnieri J, Langlois O, Sabatier J, Kalamarides M, Menei P, Club de Neuro-Oncologie de la Société Française de Neurochirurgie (2004) French neurosurgical practice in Neuro-Oncology (national survey—part I). Neurochirurgie 50:540–547

    Article  PubMed  CAS  Google Scholar 

  27. Elia-Pasquet S, Provost D, Jaffré A, Loiseau H, Vital A, Kantor G, Maire JP, Dautheribes M, Darrouzet V, Dartigues JF, Brochard P, Baldi I, Work Group (2004) Incidence of central nervous system tumors in Gironde, France. Neuroepidemiology 23:110–117. doi:10.1159/000075953

    Article  PubMed  Google Scholar 

  28. Hoffman S, Propp JM, McCarthy BJ (2006) Temporal trends in incidence of primary brain tumors in the United States, 1985–1999. Neuro-oncol 8:27–37. doi:10.1215/S1522851705000323

    Article  PubMed  Google Scholar 

  29. ENCR, European Network of Cancer Registries (1998) Recommendations for coding Tumors of the Brain and Central Nervous System. Available at http://www.encr.com.fr/Activities/Development and Recommendations on Cancer Registration and Standards/Working Groups: Tumors of the Brain and Central Nervous System crossed PDF link: English. Distributed in 1998

  30. Kramárová E, Stiller CA (1996) The international classification of childhood cancer. Int J Cancer 68:759–765. doi:10.1002/(SICI)1097-0215(19961211)68:6<759::AID-IJC12>3.0.CO;2-W

    Article  PubMed  Google Scholar 

  31. Steliarova-Foucher E, Stiller C, Lacour B, Kaatsch P (2005) International classification of childhood cancer, third edition. Cancer 103:1457–1467. doi:10.1002/cncr.20910

    Article  PubMed  Google Scholar 

  32. Gatta G, Capocaccia R, Stiller C, Kaatsch P, Berrino F, Terenziani M, EUROCARE Working Group (2005) Childhood cancer survival trends in Europe: a EUROCARE working group study. J Clin Oncol 23:3742–3751. doi:10.1200/JCO.2005.00.554

    Article  PubMed  Google Scholar 

  33. Pritchard-Jones K, Kaatsch P, Steliarova-Foucher E, Stiller CA, Coebergh JW (2006) Cancer in children and adolescents in Europe: developments over 20 years and future challenges. Eur J Cancer 42:2183–2190. doi:10.1016/j.ejca.2006.06.006

    Article  PubMed  CAS  Google Scholar 

  34. Steliarova-Foucher E, Stiller C, Kaatsch P, Berrino F, Coebergh JW, Lacour B, Parkin M (2004) Geographical patterns and time trends of cancer incidence and survival among children and adolescents in Europe since the 1970s (the ACCISproject): an epidemiological study. Lancet 364:2097–2105. doi:10.1016/S0140-6736(04)17550-8

    Article  PubMed  Google Scholar 

  35. Desandes E, Lacour B, Sommelet D, Buemi A, Danzon A, Delafosse P, Grosclaude P, Mace-Lesech J, Raverdy-Bourdon N, Tretarre B, Velten M, Brugieres L (2004) Cancer incidence among adolescents in France. Pediatr Blood Cancer 43:742–748. doi:10.1002/pbc.20106

    Article  PubMed  Google Scholar 

  36. Desandes E, Lacour B, Sommelet D, Danzon A, Delafosse P, Grosclaude P, Mace-Lesech J, Maarouf N, Marr A, Raverdy-Bourdon N, Tretarre B, Velten M, Brugieres L (2006) Cancer survival among adolescents in France. Eur J Cancer 42:403–409. doi:10.1016/j.ejca.2005.07.035

    Article  PubMed  Google Scholar 

  37. NCI–NIH–SEER National Cancer Institute–US National Institutes of Health–Surveillance Epidemiology and End Results website. Available at http://seer.cancer.gov/iccc

  38. Bleyer WA (1999) Epidemiologic impact of children with brain tumors. Childs Nerv Syst 15:758–763. doi:10.1007/s003810050467

    Article  PubMed  CAS  Google Scholar 

  39. Farinotti M, Ferrarini M, Solari A, Filippini G (1998) Incidence and survival of childhood CNS tumors in the region of Lombardy, Italy. Brain 121:1429–1436. doi:10.1093/brain/121.8.1429

    Article  PubMed  Google Scholar 

  40. Kuratsu J, Ushio Y (1996) Epidemiological study of primary intracranial tumors in childhood. A population-based survey in Kumamoto Prefecture, Japan. Pediatr Neurosurg 25:240–246. doi:10.1159/000121132

    Article  PubMed  CAS  Google Scholar 

  41. Nishi M, Miyake H, Takeda T, Hatae Y (1999) Epidemiology of childhood brain tumors in Japan. Int J Oncol 15:721–725

    PubMed  CAS  Google Scholar 

  42. Hjalmars U, Kulldorff M, Wahlqvist Y, Lannering B (1999) Increased incidence rates but no space-time clustering of childhood astrocytoma in Sweden, 1973–1992: a population-based study of pediatric brain tumors. Cancer 85:2077–2090

    PubMed  CAS  Google Scholar 

  43. Rorke LB, Schut L (1989) Introductory survey of pediatric brain tumors. In: McLaurin RL, Schut L, Venes JL, Epstein F (eds) Pediatric neurosurgery, 2nd edn. Saunders, Philadelphia, pp 335–337

    Google Scholar 

  44. INED Institut National d’Etudes Démographiques. Available at http://www.ined.fr/ Population in figures/Metropolitan France/Population Structure/By sex and age: final data

  45. Johannesen TB, Angell-Andersen E, Tretli S, Langmark F, Lote K (2004) Trends in incidence of brain and central nervous system tumors in Norway, 1970–1999. Neuroepidemiology 23:101–109. doi:10.1159/000075952

    Article  PubMed  CAS  Google Scholar 

  46. Hilden JM, Meerbaum S, Burger P, Finlay J, Janss A, Scheithauer BW, Walter AW, Rorke LB, Biegel JA (2004) Central nervous system atypical teratoid/rhabdoid tumor: results of therapy in children enrolled in a registry. J Clin Oncol 22:2877–2884. doi:10.1200/JCO.2004.07.073

    Article  PubMed  Google Scholar 

  47. Daumas-Duport C, Beuvon F, Varlet P, Fallet-Bianco C (2000) Gliomas: WHO and Sainte-Anne hospital classifications. Ann Pathol 20:413–428

    PubMed  CAS  Google Scholar 

  48. Strother DR, Pollack IF, Fisher PG, Hunter JV, Woo SY, Pomeroy SL, Rorke LB (2002) Tumors of the central nervous system. In: Pizzo PA, Poplack DG (eds) Principles and practice of pediatric oncology, 4th edn. Williams and Wilkins, Lippincott, Baltimore, pp 752–824

    Google Scholar 

  49. Wilne S, Collier J, Kennedy C, Koller K, Grundy R, Walker D (2007) Presentation of childhood CNS tumors: a systematic review and meta-analysis. Lancet Oncol 8:685–695. doi:10.1016/S1470-2045(07)70207-3

    Article  PubMed  Google Scholar 

  50. Ge HL, Hirsch WL, Wolf GL, Rubin RA, Hackett RK (1992) Diagnostic role of gadolinium-DTPA in pediatric neuroradiology. A retrospective review of 655 cases. Neuroradiology 34:122–125. doi:10.1007/BF00588157

    Article  PubMed  CAS  Google Scholar 

  51. Jacobs AH, Kracht LW, Gossmann A, Rüger MA, Thomas AV, Thiel A, Herholz K (2005) Imaging in neurooncology. NeuroRx 2:333–347. doi:10.1602/neurorx.2.2.333

    Article  PubMed  Google Scholar 

  52. Fritz A, Percy C, Jack A, Shanmugaratnam K, Sobin L, Parkin DM, Whelan S (2000) International classification of diseases for oncology, 3rd edn. World Health Organization, Geneva

    Google Scholar 

  53. Bauchet L, Rigau V, Mathieu-Daude H, Fabbro-Peray P, Fabbro M, Chinot O, Taillandier L, Figarella-Branger D, Labrousse F, Duffau H, Honnorat J (2008) Patterns of care for 952 patients with newly diagnosed glioblastoma. J Clin Oncol 26(15S):102S abstract

    Google Scholar 

Download references

Acknowledgments

The authors thank Carol Kruchko, President of the Central Brain Tumor Registry of United States, for her assistance and comments in reviewing this work. The authors wish to acknowledge all the neurosurgeons and pathologists who completed the Card of the Record of Childhood Primary Central Nervous System Tumors in France: Aghakhani N., Ali Benali M., Alliez B., Amat D., Amlashi A., Arbez-Gindre F., Arbion F., Assaker R., Aubriot Lorton M.-H., Auque J., Autricque A., Auvigne I., Averous G., Baldet P., Bataille B., Bazin A., Beaurain J., Benezech J., Bergemer Fouquet A., Besson G., Beuvon F., Billotet C., Blond S., Boetto S., Boissonnet H., Bonyhay G., Bouillot P., Bourgeois P., Bouvier C., Brassier G., Broche C., Brunon J., Cabal P., Cahn V., Caire F., Calvet P., Cazals-Hatem D., Chapon F., Chazal J., Civit T., Colnat S., Colombat M., Comoy J., Couvelard A., Czorny A., Dam Hieu P., Daumas-Duport C, Dautheribes M., David P., Debono B., Delage Corre M., Delhaye M., Delisle M.-B., Delsol G., Derlon J.-M., Desenclos C., Desplat A., Devaux B., Di Rocco F., Diaz A., Diebold M. D., Dorfmuller G., Dran G., Dufour H., Dufour T., Dumas B., Dumollard J.-M., Durand L., Duthel R., Eimer S., El Fertit H., Emery E., Espagno C., Esposito P., Etchandy M.-P., Eyremandi R. P., Faillot T., Felix S., Fernandez C., Fesselet J., Fontaine D., Fournier D., François P., Froelich S., Fuentes J.-M., Fuentes S., Gadan R., Gaspard C., Gay G., Gigaud M., Gil Robles S., Godard J., Gontier M.-F., Goujon J.-M., Gray F., Grignon Y., Grisoli F., Guarnieri J., Guyotat J., Hallacq P., Hamlat A., Hayek G., Heitzmann A., Hennequin V., Huot J.-C., Irthum B., Jacquet G., Jan M., Jaubert F., Jouanneau E., Jouvet A., Justrabo E., Kalamarides M., Kehrli P., Kemeny J.-L., Keravel Y., Kerdraon R., Khalil T., Khouri K., Khouri S., Klein O., Kujas M., Lacroix C., Lagarrigue J., Langlois O., Lapierre F., Laquerriere A., Laurent M.-C., Le Gall F., Le Guerinel C., Le Houcq M., Lechapt E., Legars D., Lemaire J.-J., Lena G., Lepeintre J.-F., Leriche B., Lescure J.-P., Levillain P., Liguoro D., Lioret E., Listrat A., Loiseau H., Lonjon M., Lopes M., Lot G., Louis E., Maheut-Lourmière J., Maillard A., Maitre F., Maitrot D., Majek-Zakine E., Mandonnet E., Manzo N., Marchal J.-C., Marie B., Maurage C.-A., Menei P., Mercier P., Mergey E., Metellus P., Michalak S., Michiels J.-F., Milinkevitch S., Mineo J.-F., Miquel C., Mireau E., Mohr M., Mokhtari K., Morandi X., Morar S., Moreau J.-J., Moreno S., Mourier K.-L., Mottolese C., Nataf F., Neuville A., Nogues L., Noudel R., Nuti C., Page P., Paquis P., Parent M., Parker F., Pasqualini G., Patey M., Pelissou-Guyotat I., Peoc’h M., Peragut J.-C., Peruzzi P., Pierre-Kahn A., Pinelli C., Polivka M., Pommepuy I., Ponnelle T., Porhiel V., Proust F., Quintin-Roue I., Ragragui O., Rasendrarijao D., Raynaud P., Redondo A., Renjard L., Reyns N., Richard S., Richaud J., Riem T., Riffaud L., Ringenbach F., Robert G., Roche P.-H., Rodriguez M.-A., Roujeau T., Rousseaux P., Rousselet M.-C., Roux F.-E., Roux F.-X., Ruchoux M.-M., Sabatier J., Sabatier P., Saïkali S., Saint Andre J.-P., Saint Pierre G., Saint-Rose C., San Galli F., Sautreaux J.-L., Sawan B., Scavarda D., Segnarbieux F., Seigneuret E., Sindou M., Sorbara R., Sorin A., Stilhart B., Straub P., Taha S., Ternier J.-P., Tortel M.-C., Toussaint P., Touzet G., Tremoulet M., Trouillas J., Tubiana A., Uro-Coste E., Vandenbos F., Varlet P., Velut S., Vidal J., Viennet G., Vignaud J.-M., Vignes J.-R., Vinchon M., Vital A., Wager M., Weinbreck N., Zerah M. This work was conducted under the financial support of a grant from the “Ligue Nationale Contre le Cancer”, the “Associations pour la Recherche sur les Tumeurs Cérébrales (ARTC and ARTC Sud)”, the “Association des Neuro-Oncologues d’Expression Française”, the “Conseil Général de l’Hérault”, the “Groupe de Neuro-Oncologie du Languedoc Roussillon” (France), and Schering-Plough laboratory.

Author information

Authors and Affiliations

  1. Department of Neurosurgery, Department of Pediatric and Adult Neurosurgery, Centre Hospitalo-Universitaire, Hôpital Gui de Chauliac, 80 Avenue Augustin Fliche, 34-295, Montpellier cedex 5, France

    Luc Bauchet, Jorge Moritz, Hugues Duffau & Philippe Coubes

  2. Laboratory of Pathology, Centre Hospitalo-Universitaire, Montpellier, France

    Valérie Rigau

  3. Department of Epidemiology, Groupe de Neuro-Oncologie du Languedoc-Roussillon, Montpellier, France

    Hélène Mathieu-Daudé, Fabienne Bauchet & Lorelei Pallusseau

  4. Department of Epidemiology, Registre des Tumeurs de l’Hérault, Montpellier, France

    Hélène Mathieu-Daudé & Brigitte Trétarre

  5. Department of Biostatistics, Institut Universitaire de Recherche Clinique, Montpellier, France

    Pascale Fabbro-Peray

  6. Department of Pediatric Oncology, Centre Hospitalo-Universitaire, Montpellier, France

    Gilles Palenzuela

  7. Department of Pathology and Neuropathology, Centre Hospitalo-Universitaire, Marseille, France

    Dominique Figarella-Branger

  8. Department of Pediatric Neurosurgery, Necker Enfants Malades Hospital, Paris, France

    Stéphanie Puget

  9. Department of Pathology and Neuropathology, Centre Hospitalo-Universitaire, Limoges, France

    François Labrousse

  10. Department of Pediatric Neurosurgery, Centre Hospitalo-Universitaire, Lille, France

    Patrick Dhellemmes

Authors
  1. Luc Bauchet
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Valérie Rigau
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hélène Mathieu-Daudé
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Pascale Fabbro-Peray
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Gilles Palenzuela
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Dominique Figarella-Branger
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Jorge Moritz
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Stéphanie Puget
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Fabienne Bauchet
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Lorelei Pallusseau
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Hugues Duffau
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Philippe Coubes
    View author publications

    You can also search for this author in PubMed Google Scholar

  13. Brigitte Trétarre
    View author publications

    You can also search for this author in PubMed Google Scholar

  14. François Labrousse
    View author publications

    You can also search for this author in PubMed Google Scholar

  15. Patrick Dhellemmes
    View author publications

    You can also search for this author in PubMed Google Scholar

Consortia

Société Française de Neurochirurgie Pédiatrique

Société Française de Neurochirurgie

Société Française de Neuropathologie

Association des Neuro-Oncologues d’Expression Française

Corresponding author

Correspondence to Luc Bauchet.

Additional information

Luc Bauchet, Valérie Rigau are equally contributed to this work.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bauchet, L., Rigau, V., Mathieu-Daudé, H. et al. Clinical epidemiology for childhood primary central nervous system tumors. J Neurooncol 92, 87–98 (2009). https://doi.org/10.1007/s11060-008-9740-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11060-008-9740-0

Keywords

Search

Navigation