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Involvement of host regulatory pathways during geminivirus infection: a novel platform for generating durable resistance

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Abstract

Geminiviruses are widely distributed throughout the world and cause devastating yield losses in almost all the economically important crops. In this review, the newly identified roles of various novel plant factors and pathways participating in plant–virus interaction are summarized with a particular focus on the exploitation of various pathways involving ubiquitin/26S proteasome pathway, small RNA pathways, cell division cycle components, and the epigenetic mechanism as defense responses during plant–pathogen interactions. Capturing the information on these pathways for the development of strategies against geminivirus infection is argued to provide the basis for new genetic approaches to resistance.

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Acknowledgments

We are grateful to the Director, National Institute of Plant Genome Research (NIPGR), New Delhi, India for providing us the facilities. The authors’ works in this area are supported by the core grant of NIPGR. We thank Dr. Senthil-Kumar Muthappa, NIPGR for critically reading the manuscript. Ms. Namisha Sharma and Mr. Mehanathan Muthamilarasan acknowledge the award of Junior Research Fellowship from Department of Biotechnology, New Delhi and University Grants Commission, New Delhi, respectively.

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The authors declare no competing interest.

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  1. Pranav Pankaj Sahu

    Present address: School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

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  1. National Institute of Plant Genome Research (NIPGR), Aruna Asaf Ali Marg, New Delhi, 110 067, India

    Pranav Pankaj Sahu, Namisha Sharma, Swati Puranik, Mehanathan Muthamilarasan & Manoj Prasad

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Sahu, P.P., Sharma, N., Puranik, S. et al. Involvement of host regulatory pathways during geminivirus infection: a novel platform for generating durable resistance. Funct Integr Genomics 14, 47–58 (2014). https://doi.org/10.1007/s10142-013-0346-z

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