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The features that distinguish lichenases from other polysaccharide-hydrolyzing enzymes and the relevance of lichenases for biotechnological applications

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Abstract

The main specific features of β-1,3-1,4-glucanases (or lichenases, EC 3.2.1.73), the enzymes that in a strictly specific manner hydrolyze β-glucans of many cereal species and lichens containing β-1,3 and β-1,4 bonds, are reviewed as well as the current strategies used for their protein design, which have been successfully applied to make lichenases more attractive and promising for biocatalytic conversion of biomass, in particular, in the areas of their biotechnological application, such as brewing industry, animal feed manufacture, and biofuel production, which will in future allow these technologies to be economically and ecologically beneficial.

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Funding

The work was supported by the Russian Foundation for Basic Research (project no. 16-34-00249; AAT).

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Authors and Affiliations

  1. Institute of Plant Physiology, Russian Academy of Sciences, ul. Botanicheskaya 35, Moscow, 127276, Russia

    Irina V. Goldenkova-Pavlova & Alexander А. Tyurin

  2. Department of Genetics and Biotechnology, Russian State Agrarian University–Moscow Timiryazev Agricultural Academy, ul. Timiryazevskaya 49, Moscow, 127550, Russia

    Irina V. Goldenkova-Pavlova & Alexander А. Tyurin

  3. Department of Biophysics and Molecular Biology, Baku State University, Zahid Khalilov st. 23, 114, Baku, AZ, Azerbaijan

    Orkhan N. Mustafaev

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  1. Irina V. Goldenkova-Pavlova
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  2. Alexander А. Tyurin
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  3. Orkhan N. Mustafaev
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Correspondence to Irina V. Goldenkova-Pavlova.

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Goldenkova-Pavlova, I.V., Tyurin, A.А. & Mustafaev, O.N. The features that distinguish lichenases from other polysaccharide-hydrolyzing enzymes and the relevance of lichenases for biotechnological applications. Appl Microbiol Biotechnol 102, 3951–3965 (2018). https://doi.org/10.1007/s00253-018-8904-x

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  • DOI: https://doi.org/10.1007/s00253-018-8904-x

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