Abstract
The sugar alcohol d-arabitol is one of the Department of Energy’s top twelve bio-based building block chemicals. In this study, we found that the oleaginous yeast Rhodosporidium toruloides IFO0880 produces d-arabitol during growth on xylose in nitrogen-rich medium. Efficient xylose utilization was a prerequisite for extracellular d-arabitol production. During growth in complex media, R. toruloides produced 22 ± 2, 32 ± 2, and 49 ± 2 g/L d-arabitol from 70, 105, and 150 g/L xylose, respectively. In addition, we found that R. toruloides could potentially be used for the co-production of lipids and d-arabitol from xylose. These results demonstrate that R. toruloides can be used to produce multiple value-added chemicals from xylose.
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This work was supported by the Energy Biosciences Institute OO3G18. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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Jagtap, S.S., Rao, C.V. Production of d-arabitol from d-xylose by the oleaginous yeast Rhodosporidium toruloides IFO0880. Appl Microbiol Biotechnol 102, 143–151 (2018). https://doi.org/10.1007/s00253-017-8581-1
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DOI: https://doi.org/10.1007/s00253-017-8581-1