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Colorimetric detection of oligonucleotides using a polydiacetylene vesicle sensor

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Abstract

A new system for the colorimetric detection of oligonucleotides was developed using polydiacetylene vesicles, which play the dual role of an indicator of color transition and an amplification tag. The results are of significance in understanding the mechanism of color transition of biological recognition in polydiacetylene systems and in designing new biosensors.

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Acknowledgements

This research was supported by the National Natural Science Foundation of China (NSFC, No.20443011), Northeast Normal University, China, and Science and Technology Office of Jilin province.

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Authors and Affiliations

  1. Chemistry Department, Northeast Normal University, Changchun 130024, P. R. China

    Chungang Wang & Zhanfang Ma

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  1. Chungang Wang
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  2. Zhanfang Ma
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Correspondence to Zhanfang Ma.

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Wang, C., Ma, Z. Colorimetric detection of oligonucleotides using a polydiacetylene vesicle sensor. Anal Bioanal Chem 382, 1708–1710 (2005). https://doi.org/10.1007/s00216-005-3345-7

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  • DOI: https://doi.org/10.1007/s00216-005-3345-7

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