Abstract
Since several decennia, the transport of Na+ across the epithelium of frog skin has been the subject of numerous studies (Lindemann and Voûte 1976). Particularly, special interest was given to the mechanisms involved in uptake of Na+ across the apical barrier, which was found to be the rate limiting step in Na+ translocation from the mucosal to serosal compartment (Biber and Curran 1970). It was generally accepted that the apical membranes were mainly permeable for Na+ and did not display a measurable permeability for K+ (Koefoed-Johnsen and Ussing 1958). Recently, we found that the apical cell membranes of the skin of frog species Rana temporaria have also a significant K+ conductance (Zeiske and Van Driessche 1979). However, the permeability for K+ varied enormously among frogs. This might have been the reason for the ignorance about this pathway during several decades of investigations of the frog skin epithelium.
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References
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© 1985 Springer-Verlag Berlin Heidelberg
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Van Driessche, W., Zeiske, W. (1985). Apical K+ Channels in Frog Skin: A Pathway for K+ Excretion. In: Gilles, R., Gilles-Baillien, M. (eds) Transport Processes, Iono- and Osmoregulation. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70613-4_6
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DOI: https://doi.org/10.1007/978-3-642-70613-4_6
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