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K+-permeability of the outer border of the frog skin (R. temporaria)

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Summary

Skins fromRana temporaria, investigated with microelectrode techniques in the absence of Na uptake across the outer border (Na-free epithelial solution or amiloride), were found to be permeable to K+ at the apical membrane in 10–20% of the experiments. Full development of the K+-permeable state requires the absence of Na+ uptake for certain periods of time, which suggests that the K+-permeability of the apical membrane is higher at lower intracellular [Na]. The addition of Ba++ reduces the K+-permeability of the apical membrane. These skins may provide a model for the study of transcellular K+ movements.

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Authors and Affiliations

  1. Department of Physiology, University of Munich, D-8000, Munich 2, Germany

    Wolfram Nagel & Walter Hirschmann

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  1. Wolfram Nagel
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  2. Walter Hirschmann
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Nagel, W., Hirschmann, W. K+-permeability of the outer border of the frog skin (R. temporaria). J. Membrain Biol. 52, 107–113 (1980). https://doi.org/10.1007/BF01869115

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  • DOI: https://doi.org/10.1007/BF01869115

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