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Essentials of Apoptosis

A Guide for Basic and Clinical Research

  • Book
  • © 2003

Overview

Editors:
  1. Xiao-Ming Yin

    1. Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Zheng Dong

    1. Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-x
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  2. Molecules and Pathways of Apoptosis

    1. Front Matter

      Pages 1-1
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    2. Caspases

      • Brona M. Murphy, Seamus J. Martin
      Pages 3-12

    3. Bcl-2 Family Proteins

      • Xiao-Ming Yin, Wen-Xing Ding, Yongge Zhao
      Pages 13-27

    4. Inhibitors of Apoptosis Proteins

      • Peter Liston, Wai Gin Fong, Robert G. Korneluk
      Pages 29-46

    5. Structural Biology of Programmed Cell Death

      • Yigong Shi
      Pages 47-65

    6. The Death Receptor Family and the Extrinsic Pathway

      • Maria Eugenia Guicciardi, Gregory J. Gores
      Pages 67-84

    7. The Mitochondrial Apoptosis Pathway

      • Bruno Antonsson
      Pages 85-99

    8. From Caspases to Alternative Cell-Death Mechanisms

      • Marja Jäättelä, Marcel Leist
      Pages 101-122

  3. Apoptosis in Action

    1. Front Matter

      Pages 123-123
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    2. Apoptosis in Plants, Yeast, and Bacteria

      • Ron Mittler, Vladimir Shulaev
      Pages 125-133

    3. Programmed Cell Death in C. elegans

      • Yi-Chun Wu, Ding Xue
      Pages 135-144

    4. Cell Death in Drosophila

      • Sujin Bao, Ross L. Cagan
      Pages 145-161

    5. Cell Death in Mammalian Development

      • Chia-Yi Kuan, Keisuke Kuida
      Pages 163-175

    6. Apoptosis and Cancer

      • Sean L. O’Connor, Fermin Briones, Nikhil S. Chari, Song H. Cho, Rebecca L. Hamm, Yoshihiko Kadowaki et al.
      Pages 177-199

    7. Cell Death in Immune, Inflammatory, and Stress Responses

      • J. John Cohen, Maria D. Devore, Mile Cikara, Elizabeth A. Dowling
      Pages 201-210

    8. Cell-Death Mechanisms in Neurodegenerative Diseases

      • R. Anne Stetler, Jun Chen
      Pages 211-224

    9. Apoptosis in Ischemic Disease

      • Zheng Dong, Manjeri A. Venkatachalam
      Pages 225-236

  4. Approaches to the Study of Apoptosis

    1. Front Matter

      Pages 237-237
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    2. Analysis of Apoptosis

      • Li Bai, Jinzhao Wang, Xiao-Ming Yin, Zheng Dong
      Pages 239-251
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Keywords

About this book

Basic and clinical investigators systematically compile a comprehensive but concise summary of essential, up-to-date information about apoptosis. The authors present the concepts, the molecular architecture, the biochemical pathways, and the pathophysiological significance of apoptosis. In addition, standard biochemical and cell biologic approaches to apoptosis research are described as a guideline for bench work, with clinical applications detailed for immune disorders, cancer, ischemia/reperfusion injury, and neuronal degeneration.

Reviews

"...will be valuable to toxicologists, who need to understand the significance of the particular mechanisms of cell death." - BTS Newsletter

Editors and Affiliations

  • Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, USA

    Xiao-Ming Yin

  • Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta, USA

    Zheng Dong

Bibliographic Information

  • Book Title: Essentials of Apoptosis

  • Book Subtitle: A Guide for Basic and Clinical Research

  • Editors: Xiao-Ming Yin, Zheng Dong

  • DOI: https://doi.org/10.1007/978-1-59259-361-3

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Humana Press 2003

  • eBook ISBN: 978-1-59259-361-3Published: 27 February 2003

  • Edition Number: 1

  • Number of Pages: X, 259

  • Topics: Cell Biology

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