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Catecholamine-Peptide Interactions in the Hypothalamus

  • Conference paper
Morphology of Hypothalamus and Its Connections

Part of the book series: Current Topics in Neuroendocrinology ((CT NEUROENDOCRI,volume 7))

Abstract

Besides the neurohypophyseal hormones oxytocin (OT) and vasopressin (VP), which belong to the classic neurosecretory systems, several other kinds of biologically active peptide have been detected in the mammalian hypothalamus. Of the latter peptides, the following are known to be present in the hypothalamus:

  1. 1.

    Hypophyseotropic hormones, or so-called hypothalamic hormones — thyrotropin-releasing hormone (TRH); luteinizing hormone-releasing hormone (LHRH); corticotropin-releasing hormone (CRH, CRF); somatostatin (somatotropin release-inhibiting hormone, SRIF); and growth hormone-releasing factor (GRF)

  2. 2.

    Anterior pituitary hormones — corticotropin (ACTH) and others

  3. 3.

    Opioid peptides — endorphins, enkephalins, and dynorphins

  4. 4.

    Gastrointestinal peptides — neurotensin (NT), substance P,

  5. 5.

    Peptides in a central angiotensin system.

The work on which this study was based was supported by grants (Nos. 57570025 and 59480092) from the Japanese Ministry of Education, Science, and Culture

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Authors and Affiliations

  1. Department of Anatomy, Showa University School of Medicine, Hatanodai, Shinagawaku, Tokyo 142, Japan

    Y. Nakai, S. Shioda, H. Ochiai & K. Kozasa

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  1. Y. Nakai
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  2. S. Shioda
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  3. H. Ochiai
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  4. K. Kozasa
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  1. Pharmakologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 366, 6900, Heidelberg, Germany

    Detlev Ganten M.D., Ph.D.

  2. Rockefeller University, York Avenue, and 66th Street, New York, NY, 10021, USA

    Donald Pfaff Ph.D.

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Nakai, Y., Shioda, S., Ochiai, H., Kozasa, K. (1986). Catecholamine-Peptide Interactions in the Hypothalamus. In: Ganten, D., Pfaff, D. (eds) Morphology of Hypothalamus and Its Connections. Current Topics in Neuroendocrinology, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71461-0_4

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