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Zusammenfassung

Zur Pränataldiagnostik im weiteren Sinne gehören alle Untersuchungen, die im Rahmen der Mutterschaftsvorsorge mit dem Ziel, Informationen über den Gesundheitszustand des Embryos bzw. Fetus zu erhalten, durchgeführt werden.

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Literatur

  • Ager RP, Oliver RW (1986) The risk of midtrimester amniocentesis, being a comparative, analytical review of the major clinical studies. Salford University Press

    Google Scholar 

  • Aitken DA, Crossley JA (1995) Prenatal screening - biochemical. In: Whittle MJ, Connor JM (eds) Prenatal diagnosis in obstetric practice. Blackwell, Oxford, pp 12–29

    Google Scholar 

  • Allan LD, Sharland GK, Chita SK, Lockhart S, Maxwell DJ (1991) Chromosomal anomalies in fetal congenital heart disease. Ultrasound Obstet Gynecol 1:8–11

    Article  PubMed  CAS  Google Scholar 

  • Allan LD, Sharland GK, Milburn A, Lockhart SM, Groves AM, Anderson RH, Cook AC, Fagg NLK (1994) Prospective diagnosis of 1006 consecutive cases of congenital heart disease in the fetus. J Am Coll Cardiol 23:1452–1458

    Article  PubMed  CAS  Google Scholar 

  • Anderson RL, Goldberg JD, Golbus MS (1991) Prenatal diagnosis in multiple gestation: zo years experience with amniocentesis. Prenat Diagn 11:263–270

    Article  PubMed  CAS  Google Scholar 

  • Assel BG, Lewis SM, Dickermann LH, Park VM, Jassani MN (1992) Single-operator com- parison of early and mid-second-trimester amniocentesis. Obst Gynecol 79:940–944

    CAS  Google Scholar 

  • Association of Clinical Cytogenetics Working Party on Chorionic Villi in Prenatal Diagnosis (1994) Cytogenetic analysis of chorionic villi for prenatal diagnosis: an ACC collaborative study of U.K. data. Prenatal Diagn 14:363–379

    Article  Google Scholar 

  • Auricchio A, Brancolini V, Casari G, Milla PJ, Smith VV, Devoto M, Ballabio A (1996) The locus for a novel syndromic form of neuronal intestinal pseudoobstruction maps to Xq28. Am J Hum Genet 58:743–748

    PubMed  CAS  Google Scholar 

  • Beck AD (1971) The effect of intrauterine urinary obstruction upon the development of the fetal kidney. J Urol 105:784

    PubMed  CAS  Google Scholar 

  • Benacerraf BR (1998) Ultrasound of fetal syndromes. Churchill Livingstone, Edinburgh

    Google Scholar 

  • Benacerraf BR, Barss VA, Laboda LA (1985) A sonographic sign for the detection in the second trimester of the fetus with Down’s Syndrome. Am J Obstet Gynecol 151:1078–1079

    PubMed  CAS  Google Scholar 

  • Benacerraf BR, Mandell J, Estroff JA, Harlow BL, Frigoletto FD (1990) Fetal pyelectasis: a possible association with Down’s Syndrome. Obstet Gynecol 76:58–60

    PubMed  CAS  Google Scholar 

  • Benirscke K (1994) Multiple gestation: incidence, etiology and inheritance. In Creasy R, Resnik R (eds) Maternal fetal medicine, 3rd edn. Saunders, Philadelphia

    Google Scholar 

  • Benson CB, Doubilet PM, Laks MP (1993) Outcome of twin gestations following sono-graphic demonstration of the heart beats in the first trimester. Ultrasound Obstet Gynecol 3:343–345

    Article  PubMed  CAS  Google Scholar 

  • Berry SM, Gosden CM, Snijders RJM, Nicolaides KH (1990) Fetal holoprosencephaly: associated malformations and chromosomal defects. Fetal Diagn Ther 5:92–99

    Article  PubMed  CAS  Google Scholar 

  • Böhm N (1984) Kinderpathologie. Farbatlas and Lehrbuch. Schattauer, Stuttgart

    Google Scholar 

  • Bonilla-Musoles FM, Raga F, Ballester RJ, Serra V (1994) Early detection of embryonic malformations by transvaginal and colour doppler sonography. J Ultrasound Med 13:347–355

    PubMed  CAS  Google Scholar 

  • Boué J, Boué A, Lasar A (1975) Retrospective and prospective epidemiology of 1500 karyotypical spontaneous human abortions. Teratology 12:11–26

    Article  PubMed  Google Scholar 

  • Brambati B, Lanzani A, Tului L (1990) Transabdominal and transcervical chorionic villus sampling: efficiency and risk evaluation of 2411 cases. Am J Med Genet 35: 160–164

    Article  PubMed  CAS  Google Scholar 

  • Brambati B, Tului L, Cislaghi C, Alberti E (1998) First 10000 chorionic villus samplings performed on singleton pregnancies by a single operator. Prenat Diagn 18:255–266

    Article  PubMed  CAS  Google Scholar 

  • Brandenburg H, van der Meulen JHP, Jahoda MGJ, Wladimiroff JW, Niermeijer M, Habbema JDF (1994) A quantitative estimation of the effect of prenatal diagnosis in dizygotic twin pregnancies in women of advanced age. Prenat Diagn 14:243–256

    Article  PubMed  CAS  Google Scholar 

  • Braverman N, Steel G, Obie C et al. (1997) Human PEX7 encodes the peroxisomal PTS2 receptor and is responsible for rhizomelic chondrodysplasia punctata. Nature Genet 15:369–376

    Article  PubMed  CAS  Google Scholar 

  • Bromley B, Estroff JA, Sanders SP, Parad R, Roberts D, Frigoletto FD, Benacerraf BR (1992) Fetal echocardiography: Accuracy and limitations in a population at high and low risk for heart defects. Am J Gynecol 166:1473–1481

    CAS  Google Scholar 

  • Bromley B, Doubilet P, Frigoletto FD Jr, Krauss C, Estroff JA, Benacerraf BR (1994) Is fetal hyperechoic bowel on second-trimester sonogram an indication for amniocentesis? Obstet Gynecol 83:647–651

    PubMed  CAS  Google Scholar 

  • Bromley B, Liebermann E, Benacerraf BR (1996) Choroid plexus cysts: not associated with Down Syndrome. Ultrasound Obstet Gynecol 8:232–235

    Article  PubMed  CAS  Google Scholar 

  • Bromley B, Liebermann B, Benacerref BR (1997) The detection of Down syndrome using a scoring index of sonographic markers and maternal age. Ultrasound Obstet Gynecol 10:321–324

    Article  PubMed  CAS  Google Scholar 

  • Brown DL, Roberts DJ, Miller WA (1994) Left ventricular echogenic focus in the fetal heart: pathologic correlation. J Ultrasound Med 13:613–616

    PubMed  CAS  Google Scholar 

  • Brumfield CG, Davis RO, Joseph DB, Cosper P (1991) Fetal obstructive uropathies: importance of chromosomal abnormalities and associated anomalies to perinatal outcome. J Reprod Med 36:662–666

    PubMed  CAS  Google Scholar 

  • Buselmaier W, Tariverdian G (1998) Humangenetik, 2. Aufl. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Byrne DL, Marks K, Azar G, Nicolaides KH (1991) Randomized study of early amniocentesis versus chorionic villus sampling: a technical and cytogenetic comparison of 650 patients. Ultrasound Obstet Gynecol 1:235–240

    Article  PubMed  CAS  Google Scholar 

  • Byrne J, Blanc W, Warburton D, Wigger J (1984) The significance of cystic hygroma in fetuses. Hum Pathol 15:61–67

    Article  PubMed  CAS  Google Scholar 

  • Camera G, Mastroiacovo P (1982) Birth prevalence of skeletal dysplasias in the italian multicentric monitoring system for birth defects. In: Papadatos CJ, Bartsocas CS (eds) Skeletal dysplasias. Liss, New York, pp 441–449

    Google Scholar 

  • Cameron AH, Edwards JH, Derom R, Thiery M, Boelaert R (1983) The value of twin surveys in the study of malformations. Eur J Obstet Gynecol Reprod Biol 14:347–356

    Article  PubMed  CAS  Google Scholar 

  • Cameron AD, Murphy KW, McNay MB et al. (1994) Midtrimester chorionic villus sampling: an alternative approach? Am J Obstet Gynecol 171:1035–1037

    PubMed  CAS  Google Scholar 

  • Canadian Collaborative CVS Amniocentesis Clinical Trial Group (1989) Multicentre randomised clinical trial of chorion villus sampling and amniocentesis. First report. Lancet 1:1–6

    Google Scholar 

  • Chaoui R (1995) Thorax, Herz and Lunge. In: Sohn C, Holzgreve W (Hrsg) Ultraschall in Gynäkologie and Geburtshilfe. Thieme, Stuttgart

    Google Scholar 

  • Chaoui R, Gembruch U (1997) Zur Epidemiologie des kongenitalen Herzfehlers beim Feten and Neugeborenen. Gynäkologe 3:165–169

    Article  Google Scholar 

  • Chervenak FA, Isaacson G, Blakemore KJ et al. (1983) Fetal cystic hygroma. Cause and natural history. N Engl J Med 309:822

    Article  PubMed  CAS  Google Scholar 

  • Chinn A, Fitzsimmons J, Shepard JH, Fantel AG (1989) Congenital heart disease among spontaneous abortuses and stillborn fetuses: prevalence and associations. Teratology 40:475–482

    Article  PubMed  CAS  Google Scholar 

  • Chitty L, Campbell S (1992) Ultrasound screening for fetal abnormalities. In: Brock DJH, Rodeck CH, Ferguson-Smith MA (eds) Prenatal diagnosis and screening. Livingstone, London, pp 595–609

    Google Scholar 

  • Chudleigh P, Pearce JM, Campbell S (1984) The prenatal diagnosis of transient cysts of the fetal choroid plexus. Prenat Diagn 4:135–137

    Article  PubMed  CAS  Google Scholar 

  • Cohen M (1982) An update on the holoprosencephalic disorders. J Pediatr 101:865–869

    Article  PubMed  Google Scholar 

  • Cohen M (1989) Perspectives on holoprosencephaly III. Spectra distinctions, continuities and discontinuities. Am J Med Genet 34:271–288

    Article  PubMed  Google Scholar 

  • Cohen MM Jr, Gorlin RJ, Fraser FC (1997) Craniofacial disorders. In: Rimoin DL, Connor JM, Pyeritz RE (eds) Emery and Rimoin’s principles and practice of medical genetics, 3rd edn. Churchill Livingstone, Edinburgh, pp 1121–1147

    Google Scholar 

  • Connor JM, Ferguson-Smith MA (1993) Essential medical genetics, 3rd edn. Blackwell, Oxford

    Google Scholar 

  • Corteville JE, Dicke JM, Crane JP (1992) Fetal pyelectasis and Down Syndrome: is genetic amniocentesis warranted? Obstet Gynecol 79:770–772

    PubMed  CAS  Google Scholar 

  • Crombach G, Eckardstein S von, Reihs T, Röhrborn G (1995) Stellenwert der invasiven Pränataldiagnostik im ersten Trimenon im Vergleich zur Standardamniozentese. Gynäkologe 28:302–314

    PubMed  CAS  Google Scholar 

  • Crombach G, Tutschek B, Reihs T, Goecke TO (1998) Spezielle Aspekte der nicht-invasiven and invasiven Pränataldiagnostik bei Mehrlingen. Gynäkologe 31:218–228

    Article  Google Scholar 

  • Cuckle H, Wald N, Stevenson JD et al. (1990) Maternal serum alpha fetoprotein screening for open neural tube defects in twin pregnancies. Prenat Diagn 10:71–77

    Article  PubMed  CAS  Google Scholar 

  • Delhanty JDA (1994) Preimplantation diagnosis. Prenat Diagn 14:1217–1227

    Article  PubMed  CAS  Google Scholar 

  • Delia J, Gruikshank D, Keye W (1990) Fetoscopic neodymium: YAG laser occlusion of pla- cental vessels in severe twin-twin transfusion syndrome. Obstet Gynecol 75:1046–1053

    CAS  Google Scholar 

  • DeMyer W (1977) Holoprosencephaly. In: Vinken PJ, Bruyn GW (eds) Handbook of clinical neurology. Elsevier, Amsterdam (Biomedical Press, vol 30, pp 431–478)

    Google Scholar 

  • Drugan A, Johnson MP, Krivchenia EL, Evans MI (1996) Genetics and genetic counseling. In: Gall SA (ed) Multiple pregnancy and delivery. Mosby, St. Louis, pp 85–97

    Google Scholar 

  • Edery P, Pelet A, Mulligan LM et al. (1994) Long segment and short segment familial Hirschsprung’s disease: variable clinical expression at the RET locus. J Med Genet 31:602–606

    Article  PubMed  CAS  Google Scholar 

  • Egmond H van, Orye E, Praet M, Coppens M, Devloo-Blancquaert A (1988) Hypoplastic left heart syndrome and 45X-karyotype. Br Heart J 60:69–71

    Article  PubMed  Google Scholar 

  • Eiben B, Goebel R, Hansen S, Hammans W (1994) Early amniocentesis. A cytogenetic evaluation of over 1500 cases. Prenat Diagn 14:497–501

    Article  PubMed  CAS  Google Scholar 

  • Eydoux P, Choiset A, Le Porrier N et al. (1989) Chromosomal prenatal diagnosis: Study of 936 cases of intrauterine abnormalities after ultrasound assessment. Prenat Diagn 9:255–268

    Article  PubMed  CAS  Google Scholar 

  • Faber R, Abitzsch, Springer C, Stephan H, Viehweg B (1997) Haben linksventrikuläre echodichte Strukturen eine klinische Bedeutung? Ultraschall Med [Suppl]: 17

    Google Scholar 

  • Firth HV, Boyd PA, Chamberlain P, MacKenzie IZ, Lindebaum RH, Hudson SM (1991) Severe limb abnormalities after chorionic villus sampling at 65–66 days’ gestation. Lancet 337:762–763

    Article  PubMed  CAS  Google Scholar 

  • Firth HV, Boyd PA, Chamberlain PF, MacKenzie IZ, Morris-Kay GM, Huson SM (1994) Analysis of limb reduction defects in babies exposed to chorionic villus sampling. Lancet 343:1069–1071

    Article  PubMed  CAS  Google Scholar 

  • Fleischer AC, Manning FA, Jeanty P, Romero R (1996) Sonography in obstetrics and gynecology, principles and practice, 5th edn. Prentice-Hall, Upper Saddle River/NJ

    Google Scholar 

  • Gall SA (ed) (1996) Multiple pregnancy and delivery. Mosby, St. Louis

    Google Scholar 

  • Geipel A, Germer U, Gembruch U (1998) Pränatale Diagnostik der singulären Nabelschnurarterie. Ultraschall Med 18 [Supp1]: 11

    Google Scholar 

  • Gembruch U, Chaoui R (1997) Möglichkeiten und Grenzen eines Screeningprogrammes. Pränatale Diagnostik fetaler Herzfehler durch Untersuchung von „high-risk“- und „low-risk”-Kollektiven. Gynäkologe 30:191–199

    Article  Google Scholar 

  • Gembruch U, Knöpfle G, Bald R, Hansmann M (1993) Early diagnosis of fetal congenital heart disease by transvaginal echocardiography. Ultrasound Obstet Gynecol 3:310–317

    Article  PubMed  CAS  Google Scholar 

  • Gembruch U, Baschata A, Knöpfle G, Hansmann M (1996) First and early second trimester diagnosis of fetal cardiac anomalies. In: Wladimiroff JW, Pilu G (eds) Ultrasound and the fetal heart. Parthenon, New York, pp 39–46

    Google Scholar 

  • Gerhard Y, Runnebaum B (1995) Endokrine Marker zur Risikoermittlung in der Pränataldiagnostik. Gynäkol Prax 19:405–410

    Google Scholar 

  • Germer U, Baschat AA, Gembruch U (1997) Frühe fetale Echokardiographie. Gynäkologe 30:200–208

    Article  Google Scholar 

  • Ghidini A et al. (1993) The risk of second-trimester amniocentesis in twin gestations: a case control study. Am J Obstet Gynecol 169:1013–1016

    PubMed  CAS  Google Scholar 

  • Gilli G, Berry AC, Chantier C (1985) Syndromes with a renal component. Williams & Wilkins, Baltimore

    Google Scholar 

  • Gilmore DH, McNay MB (1985) Letter to the editor: spontaneous fetal loss rate in early pregnancy. Lancet II:107

    Article  Google Scholar 

  • Giorlandino C, Mobili L, Bilancioni E, D’Alessio P, Carcioppolo O, Gentili P, Vizzone A (1994) Transplacental amniocentesis: is it really a higher-risk procedure? Prenatal Diagn 14:803–806

    Article  CAS  Google Scholar 

  • Gips H (1993) Die Triple-Diagnostik/AFP im mütterlichen Serum. (Broschüren, Anschr. d. Hrsg.: Max-Planckstr. 36, 61381 Friedrichsdorf)

    Google Scholar 

  • Godfrey M, Hollister DW (1988) Type II achondrogenesis-hypochondrogenesis: Identification of abnormal Type II collagen. Am J Hum Genet 43:904

    PubMed  CAS  Google Scholar 

  • Gorlin RJ, Cohen MM Jr, Levin LS (1990) Syndromes of the head and neck, 3rd edn. Oxford University Press

    Google Scholar 

  • Graham JM Jr, Rimoin DL (1997) Abnormal body size and proportion. In: Rimoin DL, Connor JM, Pyeritz RE (eds) Emery and Rimoin’s principles and practice of medical genetics, 3rd edn. Churchill Livingstone, Edinburgh, pp 737–751

    Google Scholar 

  • Hafner E, Schluchter K, Philipp K (1995) Screening for chromosomal abnormalities in an unselected population by fetal nuchal translucency. Ultrasound Obstet Gynecol 6:330–333

    Article  PubMed  CAS  Google Scholar 

  • Hansmann M, Arabin B (1993) Nonimmune hydrops fetalis. In: Chervenak FA, Isaacson GC, Campbell S (eds) Ultrasound in obstetrics and gynecology. Little & Brown, Boston, pp 1027–1051

    Google Scholar 

  • Hansmann M, Gembruch U, Bald R et al. (1991) Fetal tachyarrhythmias: transplacental and direct treatment of the fetus - a report of 6o cases. Ultrasound Obstet Gynecol 1:162

    Article  PubMed  CAS  Google Scholar 

  • Harper PS (1993) Practical genetic counselling, 4th edn. Butterworth-Heinemann, Oxford

    Google Scholar 

  • Harrison MR et al. (1990) Antenatal intervention for congenital adenomatoid malformation. Lancet 336:965–967

    Article  PubMed  CAS  Google Scholar 

  • Heifetz SA (1984) Single umbilical artery: a statistical analysis of 237 autopsy cases and review of the literature. Perspect Pediat Pathol 8:345–352

    CAS  Google Scholar 

  • Heling KS, Chaoui R, Kirchmair F, Stady S, Bollmann R (1997) Die pränatale Diagnostik des fetalen Ileus. Gynäkol Prax 212:35–52

    Google Scholar 

  • Hildebrandt F (1995) Genetic renal diseases in children. Curr Opin Pediat 7:182–191

    Article  CAS  Google Scholar 

  • Hildebrandt F, Weber M, Brandis M (1995) Hereditäre Erkrankungen der Niere. Internist 36:254–262

    PubMed  CAS  Google Scholar 

  • Hogge WA, Hogge JS, Boehm CD (1993) Increased echogenicity in the fetal abdomen: Use of DNA analysis to establish a diagnosis of cystic fibroses. J Ultrasound Med 12:451–454

    PubMed  CAS  Google Scholar 

  • Holzgreve W (1997) Nicht invasives Serum-Screening. Vortrag auf dem 14. Lübecker Ultraschallseminar für Frauenärzte in Travemünde

    Google Scholar 

  • Holzgreve W, Miny P (1990) Transabdominale und transzervikale Chorionbiopsien. Indikationen, Techniken und bisherige Ergebnisse. Gynäkologe 23:261–265

    PubMed  CAS  Google Scholar 

  • Holzgreve W, Feiel R, Louwen F, Miny P (1993) Prenatal diagnosis and management of fetal hydrocephaly and lissencephaly. Child New Syst 9:408–412

    Article  CAS  Google Scholar 

  • Holzgreve W, Gänshirt-Ahlers D, Miny P (1995) Pränatale Diagnostik an fetalen Zellen im mütterlichen Blut. In: Becker R, Fuhrmann W, Holzgreve W, Sperling K (Hrsg) Pränatale Diagnostik und Therapie. Wissenschaftliche Verlagsgesellschaft, Stuttgart

    Google Scholar 

  • Holzgreve W, Miny P, Sehloo R, Tercanli S (1995) Maternales Serumscreening zur Erfassung kindlicher Chromosomenanomalien. Gynäkologe 28:280–288

    PubMed  CAS  Google Scholar 

  • Holzgreve W, Tercanli S, Miny P (1996) Effizienzbewertung der Pränataldiagnostikmethoden und deren Patientenselektionskriterien. Gynäkologe 29:565–572

    Google Scholar 

  • Hook EB, Fabia JJ (1978) Frequency of Down Syndrome in live births by single-year maternal age interval: results of a Massachusetts study. Teratology 17:223–228

    Article  PubMed  CAS  Google Scholar 

  • Horcher E (1998) Angeborene Bauchwanddefekte. Gynäkol Prax 22:39–47

    Google Scholar 

  • Horton WA (1992) Characterization of a type II collagen gene (COL2A1) mutation identified in cultured chondrocytes from human hypochondrogenesis. Proc Nat Acad Sci USA 89:4583

    Article  PubMed  CAS  Google Scholar 

  • How HY, Villafane J, Parihus RR, Spinnato JA (1994) Small hyperechoic foci of the fetal cardiac ventricle: a benign sonographic finding? Ultrasound Obstet Gynecol 4:205–207

    Article  PubMed  CAS  Google Scholar 

  • Hyett JA, Moscoso G, Nicolaides KH (1995) First trimester nuchal translucency and cardiac septal defects in fetuses with trisomy 21. Am J Obstet Gynecol 172:1411–1413

    Article  PubMed  CAS  Google Scholar 

  • Hyett JA, Perdu M, Sharland GK, Snijders RSM, Nicolaides KM (1997) Increased nuchal translucency at 10–14 weeks of gestation as a marker for major cardiac defects. Ultrasound Obstet Gynecol 10:242–246

    Article  PubMed  CAS  Google Scholar 

  • Kimberling WJ, Kumar S, Gabow PA, Kenyon JB, Conno CJ, Somlo S (1993) Autosomal dominant polycystic kidney disease: localization of the second gene to chromosome 4q13-q23. Genomics 18:467–472

    Article  PubMed  CAS  Google Scholar 

  • Kircheisen R, Schröder-Kurth T (1991) Familiäres Blasenmolen-Syndrom und genetische Aspekte dieser Trophoblastentwicklung. Geburtsh Frauenheilkd 51:569–571

    Article  CAS  Google Scholar 

  • Kommission für Öffentlichkeitsarbeit und ethische Fragen der Gesellschaft für Humangenetik (1993) Gegenwärtiger Stand der Diskussion zur nichtinvasiven Pränataldiagnostik von Chromosomenstörungen an fetalen Zellen aus mütterlichem Blut. Med Gen 4

    Google Scholar 

  • Kommission für Öffentlichkeitsarbeit und ethische Fragen der Gesellschaft für Humangenetik (1995) Stellungnahme zur Präimplantationsdiagnostik. Med Gen 4:420

    Google Scholar 

  • Kurtz AD, Wapner RJ, Mata J, Morgan P (1992) Twin pregnancies: accuracy of first trimes- ter abdominal US in predicting chorionicity and amnionicity. Radiology 185:759–762

    PubMed  CAS  Google Scholar 

  • Landy MJ, Weiner S, Corson SL et al. (1986) The “vanishing twin”. Ultrasonographic as- sessment of fetal disappearance in the first trimester. Am J Obstet Gynecol 155:14–19

    PubMed  CAS  Google Scholar 

  • Ledbetter DH, Martin AO, Verlinsky Y, Pergament E, Jackson L, Yang-Feng T, Schonberg SA, Gilbert F et al. (1990) Cytogenetic results of chorionic villus sampling: high success rate and diagnostic accuracy in the United States collaborative study. Am J Obstet Gynecol 162:495–501

    PubMed  CAS  Google Scholar 

  • Leiber B, Olbrich G (1996) Die klinischen Syndrome. Syndrome, Sequenzen und Syndromenkomplexe. Urban & Schwarzenberg, München

    Google Scholar 

  • Leidenberger FA (1992) Klinische Endokrinologie für Frauenärzte. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Lipitz S, Reichman B, Uval J, Shalev J, Achiron R, Barkai G, Lusky A, Mashiach S (1994) A prospective comparison of the outcome of triplet pregnancies managed expectantly or by multifetal reduction of twins. Am J Obstet Gynecol 170:874–879

    PubMed  CAS  Google Scholar 

  • Liu DTY, Jeavons B, Preston C, Pearson D (1987) A prospective study of spontaneous miscarriage in ultrasonically normal pregnancies and relevance to chorionic villus sampling. Prenatal Diagn 7:223–227

    Article  CAS  Google Scholar 

  • Machin GA (1993) Conjoined twins: implications for blastogenesis. Birth Defects 29:141–179

    PubMed  CAS  Google Scholar 

  • Mahoney B, Petty C, Nyberg D, Luthy D, Hictok D, Hirsch J (1990) The “stuck twin” phenomenon: ultrasonographic findings, pregnancy outcome and management with serial amniocentesis. Obstet Gynecol 77:537–540

    Google Scholar 

  • Main DM, Mennuti MT (1986) Neural tube defects: issues in prenatal diagnosis and counselling. Obstet Gynecol 67:1–16

    PubMed  CAS  Google Scholar 

  • Martuciello G, Bicocchi MP, Dodero P et al. (1992) Total colonic aganglionosis with inter-stitial deletion of the long arm of chromosomeio. Pediat Surg Int 7: 308–310

    Google Scholar 

  • McFadyen IR (1989) Early fetal loss. In: Rodeck CH (ed) Fetal medicine. Blackwell, Oxford

    Google Scholar 

  • Meinel K (1985) Sonoanatomische Untersuchungen zum Nachweis oder Ausschluß kindlicher Fehlbildungen im zweiten Schwangerschaftstrimester. Habilitationsschrift, Universität Leipzig

    Google Scholar 

  • Meinel K (1995) Skelett-und Muskelsystem. In: Sohn C, Holzgreve W (Hrsg) Ultraschall in Gynäkologie und Geburtshilfe, Thieme, Stuttgart

    Google Scholar 

  • Mennicke K, Schwinger E (1997) Genetische Aspekte kongenitaler fetaler Herzerkrankungen. Gynäkologe 3o:181–189

    Article  Google Scholar 

  • Meyers C, Elias S, Arrabal P (1995) Congenital anomalies and pregnancy loss. In: Keith LG, Papiernik E, Keith DM, Luke B (eds) Multiple pregnancy: epidemiology, gestation and perinatal outcome. Parthenon, New York, pp 73–92

    Google Scholar 

  • Miny P, Hammer P, Schloo R, Horst J, Tercanli S, Gerlach B, Holzgreve W (1991) Pränatale Diagnostik an Chorionzotten und Placentapunktaten vom ersten bis dritten Schwangerschaftstrimenon: Diagnostische Zuverlässigkeit von Chromosomenuntersuchungen. Geburtsh Frauenheilkd 51:694–703

    Article  CAS  Google Scholar 

  • Moore JC, Nur K (1986) An international survey of gastroschisis and omphalocele (490 cases). Nature and distribution of additional malformations. Pediat Surg Internat 1:46–50

    Article  Google Scholar 

  • Moore KL (1993) Embryologie. Lehrbuch und Atlas der Entwicklungsgeschichte des Menschen. Schattauer, Stuttgart

    Google Scholar 

  • Morrow RJ, Whittle MJ, McNay MB et al. (1993) Prenatal diagnosis and management of anterior abdominal wall defects in the west of Scotland. Prenat Diagn 13:111–116

    Article  PubMed  CAS  Google Scholar 

  • Mortimer G (1990) Hydatiform mole. In: Buyse ML (ed) Birth defects Encyclopedia. Blackwell, Oxford, pp 884–886

    Google Scholar 

  • MRC Vitamin Study Research Group (1991) Prevention of neural tube defects: Results of the Medical Research Council Study. Lancet 338:131–137

    Article  Google Scholar 

  • MRC Working Party on the Evaluation of Chorion Villus Sampling (1991) Medical Research Council European Trial of chorion villus sampling. Lancet I:1491–1499

    Google Scholar 

  • Müller S (1996) Anmerkungen zur rechtlichen Situation der Präimplantationsdiagnostik in Deutschland. Med Gen 8:272–273

    Google Scholar 

  • Myrianthopoulos NC (1975) Congenital malformations in twins: epidemiologic survey. Birth Defects 11:1–39

    CAS  Google Scholar 

  • Nanagas JC (1925) A comparison of the growth of the body dimensions of anencephalic human fetuses with normal fetal growth as determined by graphic analysis: an empirical formula. Am J Anat 35:455–494

    Article  Google Scholar 

  • Nava S, Godmilow L, Reeser S, Ludominky A, Donnenfeld AE (1994) Significance of sono-graphically detected second trimester choroid plexus cysts: a series of 211 cases and a review of the literature. Ultrasound Obstet Gynecol 4:448–451

    Article  PubMed  CAS  Google Scholar 

  • Neilson IR, Russo P, Laberge JM et al. (1991) Congenital adenomatoid malformation of the lung, current management and progress. J Pediat Surg 26:975–981

    Article  PubMed  CAS  Google Scholar 

  • Nicolaides KH (1994) Screening for fetal chromosomal abnormalities: need to change the rules. Ultrasound Obstet Gynecol 4:353–354

    Article  PubMed  CAS  Google Scholar 

  • Nicolaides KH, Campbell S, Gabbe SG, Guidetti R (1986) Ultrasound screening for spina bifida: cranial and cerebellar signs. Lancet II:72–74

    Article  Google Scholar 

  • Nicolaides KH, Berry S, Snijders RIM, Thorpe-Beeston JG, Gosden CM (1990) Fetal lateral cerebral ventriculomegaly: associated malformations and chromosomal defects. Fetal Diagn Ther 5:5–14

    Article  PubMed  CAS  Google Scholar 

  • Nicolaides KH, Snijders RIM, Gosden CM, Berry C, Campbell S (1992a) Ultrasonographically detectable markers of fetal chromosomal abnormalities. Lancet 340:704–707

    Article  CAS  Google Scholar 

  • Nicolaides KH, Cheng H, Abbas A, Snijders RIM, Gosden GM (1992b) Fetal renal defects, associated malformations and chromosomal defects. Fetal Diagn Ther 7:1–11

    Article  CAS  Google Scholar 

  • Nicolaides KH, Snijders RIM, Cheng M, Gosden CM (1992c) Fetal gastrointestinal and abdominal wall defects: associated malformations and chromosomal defects. Fetal Diagn Ther 7:102–115

    Article  CAS  Google Scholar 

  • Nicolaides KH, Salvesen DR, Snijders RIM, Gosden CM (1993) Fetal facial defects: associated malformations and chromosomal abnormalities. Fetal Diagn Ther 8:1–9

    Article  PubMed  CAS  Google Scholar 

  • Nicolaides KH, Brizot ML, Snijders RIM (1994) Fetal nuchal translucency: ultrasound screening for fetal trisomy in the first trimester of pregnancy. Br J Obstet Gynaecol 101:906–907

    Article  Google Scholar 

  • Noble PL, Abraha HD, Snijders RIM, Sherwood R, Nicolaides KH (1996) Screening for fetal trisomy 21 in the first trimester of pregnancy: maternal serum free-hCG and fetal nuchal translucency thickness. Ultrasound Obstet Gynecol 6:390–395

    Article  Google Scholar 

  • Nora JJ, Nora AH (1991) Cardiovascular Diseases. Genetics, epidemiology and prevention. Oxford University Press

    Google Scholar 

  • Nora JJ, Nora AM (1988) Update on counseling the family with a first degree relative with a congenital heart defect. Am J Med Genet 29:127–142

    Google Scholar 

  • Nyberg DA, Kramer D, Resta RG, Kapur R (1993) Prenatal sonographic findings of trisomy 18. J Ultrasound Med 2:103–113

    Google Scholar 

  • Nyberg DA, Resta RG, Mahony BS, Dubinsky T, Luthy DA, Hickoc DE, Luthardt FW (1993) Fetal hyperechogenic bowel and Down’s Syndrome. Ultrasound Obstet Gynecol 3:330–333

    Article  PubMed  CAS  Google Scholar 

  • O’Connor DM, Gerassimides A (1996) Classification, placentation and pathology. In: Gall SA (ed) Multiple pregnancy and delivery. Mosby, St. Louis, pp 23–50

    Google Scholar 

  • Osathanondh U, Potter E (1964) Pathogenesis of polycystic kidneys. Arch Pathol 77:459

    PubMed  CAS  Google Scholar 

  • Paladini D, Calabro R, Palmieri S, D’Andrea J (1993) Prenatal diagnosis of congenital heart disease and fetal karyotyping. Obstet Gynecol 81:679–682

    PubMed  CAS  Google Scholar 

  • Pandya PP, Kondylios A, Hilbert L, Snijders RIM, Nicolaides KH (1995) Chromosomal defects and outcome in 1015 fetus with increased nuchal translucency. Ultrasound Obstet Gynecol 5:15–19

    Article  PubMed  CAS  Google Scholar 

  • Passarge E (1972) Genetic heterogeneity and recurrence risk of congenital intestinal aganglionosis. Birth Defects 8:63–67

    Google Scholar 

  • Passarge E (1993) Wither polygenic inheritance: mapping Hirschsprung disease. Nat Genet 4:325–326

    Article  PubMed  CAS  Google Scholar 

  • Pergament E (1995) Prenatal genetic diagnosis: amniocentesis and chorionic villus sampling. In: Keith LG, Papiernik E, Keith DM, Luke B (eds) Multiple pregnancy: epidemiology, gestation and perinatal outcome. Parthenon, New York, pp 313–324

    Google Scholar 

  • Pergament E, Schulman JD, Copeland K (1992) The risk and efficacy of chorionic villus sampling in multiple gestation. Prenat Diagn 12:377–384

    Article  PubMed  CAS  Google Scholar 

  • Peters DJM, Spruit L, Saris JJ et al. (1993) Chromosome 4 localization of a second gene for autosomal dominant polycystic kidney disease. Nat Genet 5:359–362

    Article  PubMed  CAS  Google Scholar 

  • Pittalis MC, Dalpra L, Torricelli F et al. (1994) The predictive value of cytogenetic diagnoses after CVS based on 486o cases with both direct and cuture methods. Prenat Diagn 14:267–278

    Article  PubMed  CAS  Google Scholar 

  • Plath H, Hansmann M (1998) Diagnostik and Therapie zwillingsspezifischer Anomalien. Gynäkologe 31:229–244

    Article  Google Scholar 

  • Potter E (1946) Bilateral renal agenesis. J Pediat 29:68

    Article  PubMed  CAS  Google Scholar 

  • Prömpeler HJ, Wilhelm C, Madjar H, Prem C, Schillinger H (1989) Prognose von sonographisch früh diagnostizierten Zwillingsschwangerschaften. Geburtsh Frauenheilkd 49:715–719

    Article  Google Scholar 

  • Puffenberger EG, Kauffman ER, Bolk S et al. (1994) Identity-by-descent and association mapping of a recessive gene for Hirschsprung disease on human chromosome 13q22. Hum Mol Genet 3:1217–1225

    Article  PubMed  CAS  Google Scholar 

  • Purdue PE, Zhang JW, Skoneczny M, Lararow PB (1997) Rhizomelic chondrodysplasia punctata is caused by deficiency of human PEX7, a homologue of the yeast PTS2 receptor. Nat Genet 15:381–384

    Article  PubMed  CAS  Google Scholar 

  • Report of Collaborative Acetylcholinesterase Study (1981) Amniotic fluid acetylcholinesterase electrophoresis as a secondary test in the diagnosis of anencephaly and open spina bifida in early pregnancy. Lancet II:321–325

    Google Scholar 

  • Rhoads GG, Jackson LG, Schlesselmann SE et al. (1989) The safety and efficacy of chorionic villus sampling for early prenatal diagnosis of cytogenetic abnormalities. N Engl J Med 320:609–617

    Article  PubMed  CAS  Google Scholar 

  • Rinke U, Koletzko B (1991) Prävention von Neuralrohrdefekten durch Folsäurezufuhr in der Frühschwangerschaft. Sonderdruck „Deutsches Ärzteblatt - Ärztliche Mitteilungen“, Heft 1/2

    Google Scholar 

  • Roach E, DeMyer W, Conneally PM et al. (1978) Holoprosencephaly. Birth data, genetic and demographic analyses of 3o families. Birth Defects 11:294

    Google Scholar 

  • Robertson FM et al. (1994) Prenatal diagnosis and management of gastrointestinal anomalies. Semin Perinat 18:182–195

    CAS  Google Scholar 

  • Rodis JF et al. (1990) Calculated risk of chromosomal abnormalities in twin gestations. Obstet Gynecol 76:1037–1041

    PubMed  CAS  Google Scholar 

  • Romero R (1990) Fetal skeletal anomalies. Radiol Clin North Am 28:75–99

    PubMed  CAS  Google Scholar 

  • Romero R, Pilu G, Jeanty P, Ghidini A, Hobbins JC (eds) (1987) Prenatal diagnosis of congenital anomalies. Appleton & Lange, East Norwalk

    Google Scholar 

  • Rosati D Guariglia (1996) Transvaginal sonographic assessment of the fetal urinary tract in early pregnancy. Ultrasound Obstet Gynecol 7:95–100

    Article  PubMed  Google Scholar 

  • Schluchter K, Wald N, Hackshaw AK, Hafner E, Liebhart E (1998) The distribution of nuchal translucency at 10–13 weeks of pregnancy. Prenat Diagn 18:281–286

    Article  Google Scholar 

  • Schneider KTM, Kaisenberg CV, Holzgreve W (Hrsg) (1994) Manual der fetalen Medizin. Springer, Berlin Heidelberg New York Tokyo

    Book  Google Scholar 

  • Schroeder-Kurth TM (1985) Die Bedeutung von Methoden, Risikoabwägung und Indikationsstellung für die pränatale Diagnostik. In: Reiter J, Theile U (Hrsg) Genetik und Moral. Grünewald, Mainz

    Google Scholar 

  • Schroeder-Kurth TM (1988) Ethische Überlegungen zur Pränataldiagnostik. Gynäkologe 21:168–173

    PubMed  CAS  Google Scholar 

  • Schroeder-Kurth TM, Hübner J (1989) Ethics and medical genetics in the Federal Republic of Germany. In: Weitz D, Fletcher JC (eds) Ethics and human genetics. A cross cultural survey in 17 nations. Springer, Berlin Heidelberg New York Tokyo, pp 156–175

    Google Scholar 

  • Sebire NJ, D’Ercole C, Hughes K, Carvalho M, Nicolaides KH (1997) Increased nuchal translucency at 10–14 weeks of gestation as a predictor of severe twin-to-twin transfusion syndrome. Ultrasound Obstet Gynecol 10:86–89

    Article  PubMed  CAS  Google Scholar 

  • Sebire NJ, Thornton S, Hughes K, Snijders RJM, Nicolaides KH (1997) The prevalence and consequences of missed abortion in twin pregnancies at 10 to 14 weeks of gestation. Br J Obstet Gynaecol 104:8847–8848

    Google Scholar 

  • Second Report of the UK Collaborative Study on Alphafetoprotein in relation to neural tube defects (1979) Amniotic fluid alphafetoprotein measurements in antenatal diagnosis of anencephaly and open spina bifida in early pregnancy. Lancet II:625–662

    Google Scholar 

  • Seoud MAF, Toner JP, Kruithoff C, Muasher SJ (1992) Outcome of twin, triplet and quadruplet in in vitro fertilization pregnancies: the Norfolk experience. Fertil Steril 57:825–834

    PubMed  CAS  Google Scholar 

  • Seppälä M, Ranta T, Geroff L, Lindgren J (1979) Alphafetoprotein in obstetrics and gynecology. In: Weitzel HK, Schneider J (eds) Alphafetoprotein in clinical medicine. Thieme, Stuttgart

    Google Scholar 

  • Sepulveda W, Sebire NJ, Hughes K, Kalogeropoulos A, Nicolaides KH (1997) Evolution of the Lambda or twin-chorionic peak sign in dichorionic twin pregnancies. Obstet Gynecol 89:439–441

    Article  PubMed  CAS  Google Scholar 

  • Serville F, Benit P, Saugier P et al. (1993) Prenatal exclusion of X-linked hydrocephalusstenoses of the aqueduct of sylvius-sequence using closely linked DNA markers. Prenat Diagn 13:435–439

    Article  PubMed  CAS  Google Scholar 

  • Sherer DM, Ghezzi F, Cohen J, Romero R (1997) Fetal skeletal anomalies. In: Fleischer AC, Manning FA, Jeanty P, Romero R (eds) Sonography in obstetrics and gynecology, principles and practice, 5th edn. Prentice-Hall, Upper Saddle River/NJ

    Google Scholar 

  • Simpson JL, Elias S (1994) Isolating fetal cells in maternal circulation for prenatal diagnosis. Prenat Diagn 14:1229–1242

    Article  PubMed  CAS  Google Scholar 

  • Smidt-Jensen S, Hahnemann N (1984) Transabdominal fine needle biopsy from chorionic villi in the first trimester. Prenat Diagn 4:163–169

    Article  PubMed  CAS  Google Scholar 

  • Smidt-Jensen S, Permin M, Philip J, Lundsteen C, Zachary JM, Fowler SE, Grüning K (1992) Randomised comparison of amniocentesis and transabdominal and transcervical chorionic villus sampling. Lancet 340:1237–1244

    Article  PubMed  CAS  Google Scholar 

  • Smidt-Jensen S, Lind A-M, Permin M, Zachary JM, Lundsteen C, Philip J (1993) Cytogenetic analysis of 2928 CVS samples and 1075 amniocenteses from randomised studies. Prenat Diagn 13:723–740

    Article  PubMed  CAS  Google Scholar 

  • Snijders RJM, Nicolaides KH (1996) Ultrasound markers for fetal chromosomal defects. Parthenon, New York

    Google Scholar 

  • Snijders RJM, Holzgreve W, Cuckle H, Nicolaides KH (1994) Maternal age-specific risks for trisomies at 9–14 weeks of gestation. Prenat Diagn 14:543–552

    Article  PubMed  CAS  Google Scholar 

  • Snijders RJM, Sebire NJ, Nicolaides KH (1995) Maternal age and gestational age specific risk for chromosomal defects. Fetal Diagn Ther 10:356–367

    Article  PubMed  CAS  Google Scholar 

  • Snijders RJM, Sebire NT, Souka A, Santiago C, Nicolaides KH (1996) Fetal exomphalos and chromosomal defects: relationship to maternal age and gestation. Ultrasound Obstet Gynecol 6:250–255

    Article  Google Scholar 

  • Spranger J (1998) Kurzripp-Polydaktylie-Syndrome. In: Adler G et al. (Hrsg) Die klinischen Syndrome, 8. Aufl. Urban & Schwarzenberg, München, S 452–454

    Google Scholar 

  • Stranc LC, Evans JA, Hamerton JL (1994) Prenatal diagnosis in Canada; a review. Prenat Diagn 14:1253–1265

    Article  PubMed  CAS  Google Scholar 

  • Stümpflen I, Stumpften A, Wimmer M, Bernaschek G (1996) Effect of detailed fetal echocardiography as part of routine prenatal ultrasonographic screening on detection of congenital heart disease. Lancet 348:854–857

    Article  PubMed  Google Scholar 

  • Szabo J, Gellen J (1990) Nuchal fluid accumulation in trisomy 21 detected by vaginosonography in first trimester. Lancet II:1133

    Article  Google Scholar 

  • Tabor A, Madsen M, Obel EB, Philip J, Bang J, Norgaard-Pedersen B (1986) Randomised controlled trial of genetic amniocentesis in 4606 low-risk women. Lancet I:1287–1293

    Article  Google Scholar 

  • The European Polycystic Kidney Disease Consortium (1994) The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. Cell 77:881–894

    Article  Google Scholar 

  • The Fetal Medicine Foundation (1997) The 10–14 week scan, theoretical course 2. (Correspondence: 8, Devonshire Place, London WIN 1 PB)

    Google Scholar 

  • Tolmie JL, McNay MB, Stephenson JBP, Doyle D, Connor JM (1987) Microcephaly: genetic counselling and antenatal diagnosis after the birth of an affected child. Am J Med Gen 27:583–594

    Article  CAS  Google Scholar 

  • Tolmie JL (1995) Chromosome disorders. In: Whittle MS, Connor JM (eds) Prenatal diagnosis in obstetric practice, 2nd edn. Blackwell, Oxford

    Google Scholar 

  • Turner GM, Twining P (1993) The facial profile in the diagnosis of fetal abnormalities. Clin Radiol 47:389–395

    Article  PubMed  CAS  Google Scholar 

  • Tutschek B, Thomas M, Williamson R, Rodeck CH (1995) Nichtinvasive Pränataldiagnostik an fetalen Zellen im mütterlichen Blut. Gynäkologe 28:289–301

    PubMed  CAS  Google Scholar 

  • Twining P (1993) Echogenic foci in the fetal heart: incidence and association with chromosomal disease. Ultrasound Obstet Gynecol 3 [Suppl 2]:Abstract 190

    Google Scholar 

  • Ville Y, Hyett J, Hecher K, Nicolaides K (1995) Preliminary experience with endoscopic laser surgery for severe twin-twin transfusion syndrome. N Engl J Med 332:224

    Article  PubMed  CAS  Google Scholar 

  • Voigt HJ, Beinder E, Caussen U (1994) Sonographische Erkennung von Hinweiszeichen für eine Chromosomenanomalie im 1. and 2. Trimenon. Ergebnisse einer prospektiven Studie. Geburtsh Frauenheilkd 54:460–467

    Article  CAS  Google Scholar 

  • Wald NJ, Cuckle HS, Densem JW et al. (1988) Maternal serum screening for Down’s Syndrome in early pregnancy. Br Med J 297:883–887

    Article  CAS  Google Scholar 

  • Wald NJ, Cuckle HS, Densem JW, Stone RB (1992) Maternal serum unconjugated oestriol and human chorionic gonadotrophin levels in pregnancies with insulin-dependent diabetes: implications for screening for Down’s syndrome. Br J Obstet Gynaecol 99:51–53

    Article  PubMed  CAS  Google Scholar 

  • Wapner RJ (1995) Genetic diagnosis in multiple pregnancies. Semin Perinatol 19:351–362

    Article  PubMed  CAS  Google Scholar 

  • Wapner RI, Johnson AG, Davis A, Urban A, Morgan P, Jackson L (1993) Prenatal diagnosis in twin gestations: a comparison between second trimester amniocentesis and first trimester chorion villus sampling. Obstet Gynecol 82:49

    PubMed  CAS  Google Scholar 

  • Ward RHT, Rodeck CH (1993) Letter to the editor: comparison of amniocentesis and transabdominal and transcervical chorionic villus sampling. Lancet 341:186–187

    Article  PubMed  CAS  Google Scholar 

  • Ward RHT, Modell B, Petrou M, Karagozlu F, Dourtsos E (1983) Method of sampling chorionic villi in first trimester of pregnancy under guidance of real time ultrasound. Br Med J 286:1542–1544

    Article  Google Scholar 

  • Wieacker P, Wilhelm C, Prömpeler H et al. (1992) Pathophysiology of polyhydramnios in twin transfusion syndrome. Fetal Diagn Ther 7:87

    Article  PubMed  CAS  Google Scholar 

  • Wiedemann HR, Kunze J (1995) Atlas der klinischen Syndrome für Klinik and Praxis, 4. Aufl. Schattauer, Stuttgart

    Google Scholar 

  • Wilson RD, Kendrick V, Wittmann BK, McGillivray BC (1984) Risk of spontaneous abortion in ultrasonically normal pregnancies. Lancet I:920–921

    Article  Google Scholar 

  • Wilson RD, Kendrick V, Wittmann BK, McGillivray BC (1984) Letter to the editor: risk of spontaneous abortion in ultrasonically normal pregnancies. Lancet II:920–921

    Article  Google Scholar 

  • Young SR, Shipley CF, Wade RV, Edwards JG, Waters M, Cantu ML, Best RG, Dennis EJ (1991) Single-center comparison of results of moo prenatal diagnoses with chorionic villus sampling and moo diagnoses with amniocentesis. Am J Obstet Gynecol 165:255–263

    PubMed  CAS  Google Scholar 

  • Zerres K, Waldherr R (1990) Zystische Nierenerkrankungen - Klassifikation and neue Aspekte. Dtsch Ärztebl 87, Heft 43

    Google Scholar 

  • Zerres K, Völpel MC, Weiß H (1984) Cystic kidneys - genetic, pathologic anatomy, clinical picture and prenatal diagnosis. Hum Genet 68:104

    Article  PubMed  CAS  Google Scholar 

  • Zerres K, Hansmann M, Krupple G, Stephan M (1985) Prenatal diagnosis of genetically determined early manifestation of autosomal-dominant polycystic kidney disease. Hum Genet 71:368

    Article  PubMed  CAS  Google Scholar 

  • Zerres K, Gembruch U, Schwanitz G, Rebel D, Bald R, Goltschlich A, Hansmann M (1990) Fetale Echokardiographie and klinische Genetik - Eine enge Wechselbeziehung. Z Kardiol 79:96–106

    PubMed  CAS  Google Scholar 

  • Zienert A, Bollmann R, Chaoui R, Bartho S (1992) Die singuläre Umbilikalarterie - Konsequenzen dieser pränatalen Diagnose. Zentralbl Gynäkol 114:131–135

    PubMed  CAS  Google Scholar 

  • Zosmer N, Bajoria R, Weiner E, Rigby M, Vaughan J, Fisk NM (1994) Clinical and echo-graphic features of in utero cardiac dysfunction in the recipient twin in twin-twin transfusion syndrome. Br Heart J 72:74

    Article  PubMed  CAS  Google Scholar 

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Tariverdian, G., Paul, M. (1999). Pränataldiagnostik. In: Genetische Diagnostik in Geburtshilfe und Gynäkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58453-4_12

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