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Parathyroid Hormone and Calcitonin

  • Chapter
Contemporary Endocrinology

Part of the book series: Contemporary Endocrinology ((COE,volume 2))

Abstract

In the course of reading and thinking a great deal about parathyroid hormone (PTH)—its purpose, its evolution, the effects of its excess and its deficiency—we have been led into speculation about the role of calcium in cellular economy. Increasingly we appreciate calcium’s critical role as a regulator in all kinds of cells and in organisms of all levels of complexity. Even the simplest organisms appear to employ calcium; it regulates chemotactic behavior1 and sporulation2 in bacteria; and it has been adapted to more and more uses in multicellular organisms. Cell aggregation, cell-cell communication, membrane integrity and permeability, microtubular assembly, cell division and growth, blood coagulation, hormone-response coupling, and electrical stimulus-response coupling, including muscle contraction and neurotransmitter release, all require calcium and are to some degree regulated by it.3

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  1. Department of Psychiatry and Biobehavioral Science, UCLA Neuropsychiatric Institute and School of Medicine, Los Angeles, California, 90024, USA

    Karen E. Kleeman

  2. Division of Nephrology, Department of Medicine, UCLA Center for the Health Sciences and School of Medicine, Los Angeles, California, 90024, USA

    Charles R. Kleeman

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  1. Harvard Medical School, Thorndike Laboratory of Harvard Medical school, Beth Israel Hospital, Boston, Massachusetts, USA

    Sidney H. Ingbar M.D. (William B. Cartle Professor of Medicine, Director) (William B. Cartle Professor of Medicine, Director)

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Kleeman, K.E., Kleeman, C.R. (1985). Parathyroid Hormone and Calcitonin. In: Ingbar, S.H. (eds) Contemporary Endocrinology. Contemporary Endocrinology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4817-7_7

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