Summary
Renal function was seen to deteriorate as total serum calcium rose in 40 patients with primary hyperparathyroidism. There is no significant difference between creatinine clearance values measured pre- and post-parathyroidectomy even after an interval of 8 years. This indicates that lowering of serum calcium by parathyroidectomy stabilises renal function, but creatinine clearance does not return to normal values once renal damage has occurred.
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Freaney, R., Casey, O.M. & Muldowney, F.P. The long-term effect of parathyroidectomy on renal function. I.J.M.S. 147, 205–209 (1978). https://doi.org/10.1007/BF02939403
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DOI: https://doi.org/10.1007/BF02939403