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Immunological Detection of Radiation Damage in DNA

  • Helen Van Vunakis

Abstract

Antibodies specific for photoproducts in nucleic acid offer many distinct advantages in detecting and estimating damage and repair in deoxyribonucleic acid (DNA). Sensitive immunoassays often facilitate the investigation of intact DNA irradiated at doses within the range affecting biological activities. When combined with techniques that allow visualization, antibodies can also be used to monitor the production and elimination of lesions in the DNA of cells and tissue sections in situ.

Keywords

Methylene Blue Radiation Damage Antigenic Determinant Rose Bengal Complement Fixation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Helen Van Vunakis
    • 1
  1. 1.Department of BiochemistryBrandeis UniversityWalthamUSA

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