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5-Methylcytosine in heterochromatic regions of chromosomes in Bovidae

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Summary

The centromeric regions of cattle, goat and sheep chromosomes bind anti-5-MeC as revealed by immunofluorescence technique, indicating concentration of 5-MeC at these heterochromatic regions. The centromere of the submetacentric X of cattle remains nearly unstained and so do the centromeres of the acrocentric X chromosomes in goat and sheep. The short arm of the cattle Y exhibits strong anti-5-MeC binding whereas the tiny Y chromosomes of goat and sheep contain no brightly fluorescent material.

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Schnedl, W., Erlanger, B.F. & Miller, O.J. 5-Methylcytosine in heterochromatic regions of chromosomes in Bovidae . Hum. Genet. 31, 21–26 (1976). https://doi.org/10.1007/BF00270395

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  • DOI: https://doi.org/10.1007/BF00270395

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