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Antibodies to the Terminal Moieties of Guanine Mononucleotides and Guanine-Containing Dinucleotides

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Nucleic Acids in Immunology

Abstract

Antibodies specific for nucleic acids have been obtained by immunizing rabbits with conjugates composed of bases, nucleosides or nucleotides covalently linked to proteins or polyamino acids. The chemical methods used to prepare such immunogens have been reviewed (Levine and Stollar, 1967) and the characteristics of some of these antibodies are considered in this volume.

Aided by grants from the NIH (AI-01940 and AI-02792) and the Charles Simon Memorial Grant for Cancer Research from the American Cancer Society (E.222). L. L. is an American Cancer Society Professor of Biochemistry and H. V. V. is a recipient of a Public Health Service Research Career Award K6-AI-2372. Publication No. 564 from the Graduate Department of Biochemistry, Brandeis University.

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© 1968 Springer-Verlag New York Inc.

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Van Vunakis, H., Seaman, E., Levine, L. (1968). Antibodies to the Terminal Moieties of Guanine Mononucleotides and Guanine-Containing Dinucleotides. In: Plescia, O.J., Braun, W. (eds) Nucleic Acids in Immunology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87668-4_6

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  • DOI: https://doi.org/10.1007/978-3-642-87668-4_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-87670-7

  • Online ISBN: 978-3-642-87668-4

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