Overview
- Systemic coverage of major aspects of apoptosis and other types of cell death in a broad range of biological systems
- Most updated and advanced knowledge in the field of cell death and survival provided by the leading experts in the fields
- Comprehensive discussion of cell death in pathogenesis of human diseases in all major organ systems
- Experimental techniques for both basic science and clinical researchers
- Suitable for both novices entering the field and seasoned researchers seeking novel ideas
- Includes supplementary material: sn.pub/extras
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Table of contents (31 chapters)
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Part I. Molecules and Pathways of Apoptosis
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Part II: Apoptosis in Model Organisms
Keywords
About this book
This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly – chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.
Reviews
From the reviews of the second edition:
"This book comprehensively reviews knowledge of the main mechanism of cell death, apoptosis, both from the molecular viewpoint and in relation to the roles of this process in mammalian physiology and pathology. … chapters are well written and scholarly in content and present the reader with a thorough and up-to-date insight into these fields. This book is highly recommended for scientists working in many areas of cell or developmental biology, as well as those involved in more clinical fields, such as neurobiology or molecular oncology." (Mike Clemens, Microbiology Today, November, 2009)
“The book ‘Essentials of Apoptosis’ is a collection of 31 review articles, covering a wide variety of approaches in studying cell death. … It enables the reader to get acquainted with many aspects of apoptosis, and impressive amounts of references cited in each of the article allows for further studies on the subject. I recommend this book to anyone seriously interested in research on programmed dell death.” (Piotr P. Stepien, Acta Biochimica Polonica, December, 2010)
“Prof. Yin and Prof. Dong … were able to cover both conceptual and practical aspects as well as both basic and applied research aspects, thus leading to translation research aspects in biomedicine, which is a crucial hot topic in modern biomedical clinic. … the potential readership is made up of the entire scientific comunity … and cellular biologists, developmental biologists, protein scientists.” (CarloAlberto Redi, European Journal of Histochemistry, Vol. 54 (e11), 2010)
“Comprehensive overview of the history and current knowledge of the study of the genetic program of cell death … . the book is to inform the basic researcher and the clinician interested in understanding how inappropriate apoptosis may underlie their area of scientific interest, and in this respect it succeeds. … a welcome addition for thecollection of a newcomer to apoptosis: in the basic research lab, a graduate student or post-doc would benefit from … the excellent reference sections provided for each chapter.” (Robert Screaton, The Canadian Journal of Neurological Science, May, 2010)
Bibliographic Information
Book Title: Essentials of Apoptosis
Book Subtitle: A Guide for Basic and Clinical Research
Editors: Zheng Dong, Xiao-Ming Yin
DOI: https://doi.org/10.1007/978-1-60327-381-7
Publisher: Humana Totowa, NJ
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2009
Hardcover ISBN: 978-1-60327-380-0Published: 04 June 2009
Softcover ISBN: 978-1-4939-5649-4Published: 23 August 2016
eBook ISBN: 978-1-60327-381-7Published: 01 July 2009
Edition Number: 2
Number of Pages: XXVI, 742
Topics: Cell Biology, Biochemistry, general, Neurosciences, Immunology, Human Physiology