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  • © 2014

Molecular Imaging of Small Animals

Instrumentation and Applications

Editors:

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  • Explores the rapidly expanding field of multimodality small-animal molecular imaging

  • Examines various imaging modalities including CT, MRI, SPECT and PET

  • Demonstrates the increasing role of in vivo small-animal imaging in understanding human molecular biology and pathophysiology

  • Includes supplementary material: sn.pub/extras

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USD 189.00
Price excludes VAT (USA)
  • ISBN: 978-1-4939-0894-3
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  • Tax calculation will be finalised during checkout
Softcover Book
USD 249.99
Price excludes VAT (USA)
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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xii
  2. Scintillation Detectors for Small-Animal Imaging

    • Tom K. Lewellen, Robert Miyaoka
    Pages 1-21
  3. Solid-State Detectors for Small-Animal Imaging

    • Paolo Russo, Alberto Del Guerra
    Pages 23-82
  4. Photon Detectors for Small-Animal Imaging Instrumentation

    • Dieter Renker, Eckart Lorenz
    Pages 83-134
  5. Design Considerations of Small-Animal SPECT Cameras

    • Steven R. Meikle, Peter L. Kench, Jianyu Lin
    Pages 135-162
  6. Design Considerations for Small Animal PET Scanners

    • Virginia Ch. Spanoudaki, Craig S. Levin
    Pages 163-187
  7. Small-Animal MRI Instrumentation

    • Andrew M. Blamire
    Pages 211-240
  8. Preclinical Optical Molecular Imaging

    • Yujie Lu, Ge Wang
    Pages 241-273
  9. Dual-Modality Preclinical SPECT/PET Instrumentation

    • Alberto Del Guerra, Nicola Belcari
    Pages 337-349
  10. Dual-Modality Preclinical SPECT/CT Instrumentation

    • Youngho Seo, Carina Mari Aparici
    Pages 351-365
  11. Dual-Modality Preclinical PET/CT Instrumentation

    • Andrew L. Goertzen, Habib Zaidi
    Pages 367-386
  12. Dual-Modality Preclinical SPECT/MRI Instrumentation

    • Douglas J. Wagenaar, Dirk Meier, Bradley E. Patt
    Pages 387-407
  13. Dual-Modality Preclinical PET/MRI Instrumentation

    • David Schlyer, Bosky Ravindranath
    Pages 409-445
  14. Animal Handling and Preparation for Imaging

    • David B. Stout
    Pages 495-516
  15. Applications of Small-Animal Imaging in Neurology and Psychiatry

    • Cindy Casteels, Habib Zaidi, Koen Van Laere
    Pages 517-546

About this book

This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development.

In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology and pathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.

 

Reviews

“Molecular Imaging of Small Animals: Instrumentation and Applications, Zaidi … examines the most important techniques used for small-animal molecular imaging, analysing every aspect of each modality. … this publication should be available in all departments of nuclear medicine and diagnostic imaging, considering that molecular imaging is already living in the present.” (Giuseppe Danilo Di Stasio and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 42, 2015)

Editors and Affiliations

  • Department of Radiology & Medical Informatics, Geneva University Hospital, Geneva, Switzerland

    Habib Zaidi

About the editor

Habib Zaidi, Ph.D is Chief Physicist and head of the PET Instrumentation & Neuroimaging Laboratory at Geneva University Hospital and faculty member at the medical school of Geneva University. He is also a Professor of Medical Physics at the University Medical Center of Groningen (The Netherlands) and visiting Professor at Ecole Nationale Supérieure d’Electronique et de ses Applications (ENSEA, France). Dr. Zaidi is actively involved in developing imaging solutions for cutting-edge interdisciplinary biomedical research and clinical diagnosis in addition to lecturing undergraduate and postgraduate courses on medical physics and medical imaging.

Bibliographic Information

  • Book Title: Molecular Imaging of Small Animals

  • Book Subtitle: Instrumentation and Applications

  • Editors: Habib Zaidi

  • DOI: https://doi.org/10.1007/978-1-4939-0894-3

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2014

  • Hardcover ISBN: 978-1-4939-0893-6

  • Softcover ISBN: 978-1-4939-5102-4

  • eBook ISBN: 978-1-4939-0894-3

  • Edition Number: 1

  • Number of Pages: XII, 760

  • Number of Illustrations: 132 b/w illustrations, 157 illustrations in colour

  • Topics: Pharmaceutics, Biotechnology, Biomedical Research

Buying options

eBook
USD 189.00
Price excludes VAT (USA)
  • ISBN: 978-1-4939-0894-3
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD 249.99
Price excludes VAT (USA)
Hardcover Book
USD 299.99
Price excludes VAT (USA)