Abstract
Following consumption of saccharin, groups of rats were injected with various doses of morphine sulfate. Although no aversion was found after one conditioning trial, repeated saccharin-morphine pairings resulted in decreases in consumption of the saccharin solution. On the average, however, the groups of rats showed only a moderate aversion, independent of the dose of morphine. Although there was little variability in consumption among rats that received the smallest dose of morphine, there was considerable individual variability among subjects receiving the larger doses. The differences between morphine-based conditioned taste aversions and aversions based on emetic USs were discussed.
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Watson, B., & Riley, A. Effects of lithium chloride and morphine sulfate on blood corticosterone levels in the rat. Paper presented at the meeting of the Canadian Psychological Association, Toronto, Ontario, June 1976.
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This research was supported by the National Research Council of Canada, Grant A-9585 to V.M.L. A.L.R. was supported by an Izaak Walton Killam postdoctoral fellowship during the conduct of this research. W.J.J. was supported by a grant from Research on Drug Abuse of Canada. The authors would like to thank Linda L. Baril, Constance M. Clarke, Janet Lord, and Barry G. Watson for their assistance throughout this research.
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Riley, A.L., Jacobs, W.J. & LoLordo, V.M. Morphine-induced taste aversions: A consideration of parameters. Psychobiology 6, 96–100 (1978). https://doi.org/10.3758/BF03326701
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DOI: https://doi.org/10.3758/BF03326701