Abstract
Fenofibrate improves the lipid profile (particularly triglyceride and high-density lipoprotein-cholesterol levels) when administered alone or combined with a statin in patients with dyslipidaemia, and is generally well tolerated. Fenofibrate appears to decrease cardiovascular events in patients with type 2 diabetes mellitus and atherogenic dyslipidaemia, and may also reduce the risk of certain microvascular outcomes in patients with type 2 diabetes, although further investigation is needed.
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Acknowledgements and Disclosures
This article was adapted from Drugs 2011; 71 (16): 1917–46,[3] and reviewed by D. Bhatnagar, Diabetes Centre, The Royal Oldham Hospital, Oldham, UK; M. Farnier, Point Médical, Rond Point de la Nation, Dijon, France.
The preparation of this article was not supported by any external funding. During the peer review process, the manufacturer of the agent under review was offered an opportunity to comment on the articles. Changes resulting from comments received were made by the authors on the basis of scientific and editorial merit.
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Keating, G.M., McKeage, K. Fenofibrate: a guide to its use in dyslipidaemia. Drugs Ther Perspect 28, 5–10 (2012). https://doi.org/10.2165/11608570-000000000-00000
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DOI: https://doi.org/10.2165/11608570-000000000-00000