Abstract
Copy number variations (CNVs) are important forms of structural variation in human and animals and can be considered as a major genetic component of phenotypic diversity. Here we used the Illumina PorcineSNP60 BeadChip V2 and a DLY [Duroc × (Large White × Landrace)] commercial hybrid population to identify 272 CNVs belonging to 165 CNV regions (CNVRs), of which 66 are new. As CNVRs are specific to origin of population, our DLY-specific data is an important complementary to the existing CNV map in the pig genome. Eight CNVRs were selected for validation by quantitative real-time PCR (qRT-PCR) and the accurate rate was high (87.25%). Gene function analysis suggested that a common CNVR may play an important role in multiple traits, including growth rate and carcass quality.
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Zhou, L.S., Li, J., Yang, J. et al. Genome-wide mapping of copy number variations in commercial hybrid pigs using a high-density SNP genotyping array. Russ J Genet 52, 85–92 (2016). https://doi.org/10.1134/S1022795415120145
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DOI: https://doi.org/10.1134/S1022795415120145