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Advances in positron emission tomography tracers related to vascular calcification

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Abstract

Microcalcification, a type of vascular calcification, increases the instability of plaque and easily leads to acute clinical events. Positron emission tomography (PET) is a new examination technology with significant advantages in identifying vascular calcification, especially microcalcification. The use of the 18F-NaF is undoubtedly the benchmark, and other PET tracers related to vascular calcification are also currently in development. Despite all this, a large number of studies are still needed to further clarify the specific mechanisms and characteristics. This review aimed at providing a summary of the application and progress of different PET tracers and also the future development direction.

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Funding

This work was supported as follows: the National Natural Science Foundation of China (82070455); the related Foundation of Jiangsu Province (BK20201225); Medical Innovation Team Project of Jiangsu Province (CXTDA2017010).

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  1. Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China

    Wenjun Yang, Zhiqi Zhong & Zhongqun Wang

  2. Department of Radiology, Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China

    Guoquan Feng

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Yang, W., Zhong, Z., Feng, G. et al. Advances in positron emission tomography tracers related to vascular calcification. Ann Nucl Med 36, 787–797 (2022). https://doi.org/10.1007/s12149-022-01771-3

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