Skip to main content

Advertisement

SpringerLink
Log in

Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents

  • Biotechnology
  • Published:
Korean Journal of Chemical Engineering Aims and scope Submit manuscript

Abstract

World-wide production of l-lysine has rapidly increased in recent years. In the industrial scale production, it is cost effective to minimize waste as many waste materials are generated during downstream processing. Therefore, the conversion of crude lysine to a more valuable product reduces waste emission. In this study, 1,5-diaminopentane (DAP, trivial name: cadaverine) was produced by l-lysine decarboxylation using Hafnia alvei. The conditions of enzymatic reaction were determined. In particular, the addition of specific detergent (Brij 56) was significantly affected in the bioconversion system. Addition of hydrophobic organic solvent improved the mixing of the reactants. Finally, an industrial crude form of lysine served as a substrate. The DAP conversion by analytical, feed and industrial crude l-lysine was 93.9%, 90.3%, and 63.8%, respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. R. Kelle, T. Hermann and B. Bathe, l-lysine production, Handbook of Corynebacterium glutamicum, CRC Press, Florida (2005).

    Google Scholar 

  2. J. Evans, Commercial amino acids, BCC Research: Market Research Reports, BIO007L (2017). https://doi.org/www.bccresearch.com

    Google Scholar 

  3. M. Elder, World markets for fermentation ingredients, BCC Research: Market Research Reports, FOD020E (2018). https://doi.org/www.bccresearch.com

    Google Scholar 

  4. L. Eggeling and M. Bott, Appl. Microbiol. Biotechnol., 99, 3387 (2015).

    Article  CAS  PubMed  Google Scholar 

  5. C. Wittmann and J. Becker, Microbiol. Monogr., 5, 39 (2007).

    Article  Google Scholar 

  6. K. E. Uffmann and M. Binder, US Patent, 6,340,486 (2002).

  7. J. Adkins, J. Jordan and D. R. Nielsen, Biotechnol. Bioeng., 110, 1726 (2015).

    Article  CAS  Google Scholar 

  8. S. Jeong, Y. J. Yeon, E. G. Choi, S. Byun, D. H. Cho, I. K. Kim and Y. H. Kim, Korean J. Chem. Eng., 33, 1530 (2016).

    Article  CAS  Google Scholar 

  9. C. G. Chae, Y. J. Kim, S. J. Lee, Y. H. Oh, J. E. Yang, J. C. Joo, K. H. Kang, Y.-A. Jang, H. Lee, A.-R. Park, B. K. Song, S.Y. Lee and S. J. Park, Biotechnol. Bioprocess Eng., 21, 169 (2016).

    Article  CAS  Google Scholar 

  10. N, Li, H. Chou, L. Yu and Y. Xu, Biotechnol. Bioprocess Eng., 19, 965 (2014).

    Article  CAS  Google Scholar 

  11. C. Wang, K. Zhang, C. Zhongjun, H. Cai and W. Honggui, Biotechnol. Bioprocess Eng., 20, 439 (2015).

    Article  CAS  Google Scholar 

  12. T. Tateno, Y. Okada, Y. Tsuchidate, T. Tanaka, H. Fukuda and A. Kondo, Appl. Microbiol. Biotechnol., 82, 115 (2009).

    Article  CAS  PubMed  Google Scholar 

  13. F. Cassan, S. Maiale, O. Masciarelli, A. Vidal, V. Luna and O. Ruiz, Eur. J. Soil Biol., 45, 12 (2009).

    Article  CAS  Google Scholar 

  14. J.-H. Kim, H.-M. Seo, G. Sathiyanarayanan, S. K. Bhatia, H.-S. Song, J. Kim, J.-M. Jeon, J.-J. Yoon, Y.-G. Kim, K. Park and Y.-H. Yang, J. Ind. Eng. Chem., 46, 44 (2017).

    Article  CAS  Google Scholar 

  15. Y. Takatsuka, Y. Yamaguchi, M. Ono and Y. Kamio, J. Bacteriol., 182, 6732 (2000).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. U. Kanjee, I. Gutsche, E. Alexopoulos, B. Zhao, M. El Bakkouri, M. Thibault, K. Liu, S. Ramachandran, J. Snider, E. F. Pai and W. A. Houry, EMBO J., 30, 931 (2011).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. M. Abercrombie, In Vitro, 6, 128 (1970).

    Article  CAS  PubMed  Google Scholar 

  18. K. Han and O. Levenspiel, Biotechnol. Bioeng., 32, 430 (1987).

    Article  Google Scholar 

  19. Z. Velioglu and R.O. Urek, Biotechnol. Bioprocess Eng., 21, 430 (2017).

    Article  CAS  Google Scholar 

  20. M. Manaargadoo-Catin, A. Ali-Cherif, J. L. Pougnas and C. Perrin, Adv. Colloid Interface Sci., 228, 1 (2016).

    Article  CAS  PubMed  Google Scholar 

  21. S.K. Hait and S. P. Moulik, J. Surfactants Deterg., 4, 303 (2001).

    Article  CAS  Google Scholar 

  22. D. Linke, Methods in Enzymol., 463, 603 (2009).

    Article  CAS  Google Scholar 

  23. S. Luche, V. Santoni and T. Rabilloud, Proteomics, 3, 249 (2003).

    Article  CAS  PubMed  Google Scholar 

  24. S.B. Kim, H.Y. Yoo, J. S. Kim and S.W. Kim, Process Biochem., 49, 2203 (2014).

    Article  CAS  Google Scholar 

  25. C. Laane, S. Boeren, K. Vos and C. Veeger, Biotechnol. Bioeng., 30, 81 (1987).

    Article  CAS  PubMed  Google Scholar 

  26. J. L. Gu, H. F. Tong and L.Y. Sun, Biotechnol. Bioprocess Eng., 22, 76 (2017).

    Article  CAS  Google Scholar 

  27. T. Hermann, J. Biotechnol., 104, 155 (2003).

    Article  CAS  PubMed  Google Scholar 

  28. A.-T. Nguyen and W.-S. Kim, Korean J. Chem. Eng., 34, 2002 (2017).

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. These authors contributed equally to this work.

Authors and Affiliations

  1. Department of Chemical Engineering, Kwangwoon University, 20 Kwangwoon-ro, Nowon-gu, Seoul, 01897, Korea

    Hanyong Kim, Yong Hwan Ki, Hiesang Sohn, Taek Lee & Chulhwan Park

  2. Department of Biotechnology, Sangmyung University, 20 Hongjimun 2-gil, Jongno-gu, Seoul, 03016, Korea

    Hah Young Yoo

  3. School of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology (UNIST), 50 UNIST-gil, Ulsan, 44919, Korea

    Yong Hwan Ki

  4. Department of Bioprocess Research, Daesang Co. Ltd., 697 Jungbudae-ro, Majang-myeon, Gyeonggi, 17384, Korea

    Il-Kwon Kim

  5. Department of Food Science and Technology, Kongju National University, 54 Daehak-ro, Yesan, Chungnam, 32439, Korea

    Eui-Hong Byun

  6. Department of Biological Engineering, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 05029, Korea

    Yung-Hun Yang

  7. Division of Chemical Engineering and Materials Science, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul, 03760, Korea

    Si Jae Park

  8. Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 04107, Korea

    Jeong-Geol Na

  9. School of Chemical and Biomolecular Engineering, Pusan National University, 2 Busandaehak-ro, 63 Beon-gil, Geumjeong-gu, Busan, 46241, Korea

    Jung Rae Kim

Authors
  1. Hanyong Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hah Young Yoo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yong Hwan Ki
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Il-Kwon Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Eui-Hong Byun
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Yung-Hun Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Si Jae Park
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Jeong-Geol Na
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Hiesang Sohn
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Taek Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Jung Rae Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Chulhwan Park
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Jung Rae Kim or Chulhwan Park.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kim, H., Yoo, H.Y., Ki, Y.H. et al. Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents. Korean J. Chem. Eng. 35, 1854–1859 (2018). https://doi.org/10.1007/s11814-018-0075-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11814-018-0075-z

Keywords

Search

Navigation