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Prevention and treatment of pancreatic fistula after pancreatic body and tail resection: current status and future directions

  • Review
  • Open Access
  • Published: 16 December 2019
  • volume 14, pages 251–261 (2020)
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Frontiers of Medicine Aims and scope Submit manuscript
Prevention and treatment of pancreatic fistula after pancreatic body and tail resection: current status and future directions
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  • Li Jiang1,
  • Deng Ning1 &
  • Xiaoping Chen2 

  • 1867 Accesses

  • 11 Citations

  • Explore all metrics

  • Cite this article

Abstract

Postoperative pancreatic fistula (POPF) is the most common and critical complication after pancreatic body and tail resection. How to effectively reduce the occurrence of pancreatic fistula and conduct timely treatment thereafter is an urgent clinical issue to be solved. Recent research standardized the definition of pancreatic fistula and stressed the correlation between POPF classification and patient prognosis. According to the literature, identification of the risk factors for pancreatic fistula contributed to lowering the rate of the complication. Appropriate management of the pancreatic stump and perioperative treatment are of great significance to reduce the rate of POPF in clinical practice. After the occurrence of POPF, the treatment of choice should be determined according to the classification of the pancreatic fistula. However, despite the progress and promising treatment approaches, POPF remains to be a clinical issue that warrants further studies in the future.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (No. 81472705).

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Authors and Affiliations

  1. Department of Biliary and Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

    Li Jiang & Deng Ning

  2. Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

    Xiaoping Chen

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Correspondence to Xiaoping Chen.

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Li Jiang, Deng Ning, and Xiaoping Chen declare no conflicts of interest. This manuscript is a review article and does not involve a research protocol requiring approval by the relevant institutional review board or ethics committee.

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Jiang, L., Ning, D. & Chen, X. Prevention and treatment of pancreatic fistula after pancreatic body and tail resection: current status and future directions. Front. Med. 14, 251–261 (2020). https://doi.org/10.1007/s11684-019-0727-3

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  • Received: 17 July 2019

  • Accepted: 12 October 2019

  • Published: 16 December 2019

  • Issue Date: June 2020

  • DOI: https://doi.org/10.1007/s11684-019-0727-3

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Keywords

  • pancreatic fistula
  • pancreatic body and tail resection
  • distal pancreatectomy

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