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Internal Morphology Evolution of Mg Wire/Poly(Lactic Acid) Composites during Degradation Process Characterized by X-Ray Computed Tomography

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Abstract

The composite rod composed of magnesium alloy wire and poly(lactic acid) (Mg wire/PLA) was prepared by hot-pressed process. The internal morphology evolution of the composites during degradation was investigated by x-ray computed tomography (XCT). Particularly, the location, amount, size, as well as sphericity of defects were visualized on the basis of XCT three-dimensional imaging technology and VGDefX algorithm. The result denoted that cracks were prone to appear near the outside location of the composites. The diameter-sphericity and volume-sphericity of defects inside the composites significantly increased after 6 weeks immersion. The alkaline degradation products in composite rods induced by the degradation of magnesium would promote the degradation of PLA and further accelerate the mechanical properties loss. Reasons for the inhomogeneity of degradation morphology were analyzed from the view of Mg wire, PLA matrix, as well as interface bonding state. Furthermore, the relationship between the evolution of degradation morphology and the attenuation of mechanical properties of the composites was presented. It is of great significance to provide theoretical guidance and method reference for in situ investigating the degradation performances of this kind of composites.

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References

  1. D.M. Ramos, R. Dhandapani, A. Subramanian, S. Sethuraman and S.G. Kumbar, Clinical Complications of Biodegradable Screws for Ligament Injuries, Mater. Sci. Eng. C, 2020, 109, p 110423.

    Article  CAS  Google Scholar 

  2. A. Gleadall, J.Z. Pan, M.A. Kruft and M. Kellomaki, Degradation Mechanisms of Bioresorbable Polyesters Part 1. Effects of Random Scission, End Scission and Autocatalysis, Acta Biomater., 2014, 10, p 2223–2232.

    Article  CAS  Google Scholar 

  3. B. Laycock, M. Nikolic, J.M. Colwell, E. Gauthier, P. Halley, S. Bottle and G. George, Lifetime Prediction of Biodegradable Polymers, Prog. Polym. Sci., 2017, 71, p 144–189.

    Article  CAS  Google Scholar 

  4. S. Prithivirajan, S. Narendranath and D. Vijay, Recent Progress in In vivo Studies and Clinical Applications of Magnesium Based Biodegradable Implants—A Review, J. Magnes. Alloy., 2021, 9, p 1147–1163.

    Article  Google Scholar 

  5. Y.X. Lai, Y. Li, H.J. Cao, J. Long, X.L. Wang, L. Li, C.R. Li, Q.Y. Jia, B. Teng, T.T. Tang, J. Peng, D. Eglin, M. Alini, D.W. Grijpma, G. Richards and L. Qin, Osteogenic Magnesium Incorporated into PLGA/TCP Porous Scaffold by 3D Printing for Repairing Challenging Bone Defect, Biomaterials, 2019, 197, p 207–219.

    Article  CAS  Google Scholar 

  6. W. Ali, A. Mehboob, M.G. Han and S.H. Chang, Experimental Study on Degradation of Mechanical Properties of Biodegradable Magnesium Alloy (AZ31) Wires/Poly(lactic acid) Composite for Bone Fracture Healing Applications, Compos. Struct., 2019, 210, p 914–921.

    Article  Google Scholar 

  7. H. Cai, X. Li, C.L. Chu, F. Xue, C. Guo, Q.S. Dong and J. Bai, Insight into the Effect of Interface on the Mechanical Properties of Mg/PLA Composite Plates, Compos. Sci. Technol., 2019, 183, p 107801.

    Article  CAS  Google Scholar 

  8. X. Li, C.L. Chu, L. Liu, X.K. Liu, J. Bai, C. Guo, F. Xue, P.H. Lin and P.K. Chu, Biodegradable Poly-lactic Acid Based-composite Reinforced Unidirectionally with High-strength Magnesium Alloy Wires, Biomaterials, 2015, 49, p 135–144.

    Article  CAS  Google Scholar 

  9. C.L. Chu, X. Li, W.D. Yu, L.Y. Han, J. Bai and F. Xue, Degradation Behaviors of PLA-matrix Composite with 20 vol% Magnesium Alloy Wires Under Static Loading Conditions, J. Mater. Sci., 2019, 54, p 4701–4709.

    Article  CAS  Google Scholar 

  10. J.L. Yan, Z.J. Qin and K. Yan, Mechanical Properties and Microstructure Evolution of Mg-6wt% Zn Alloy During Equal-Channel Angular Pressing, Metals, 2018, 8, p 841–851.

    Article  CAS  Google Scholar 

  11. J. Wang, Y. Jang, G.J. Wan, V. Giridharan, G.L. Song, Z.G. Xu, Y. Koo, P.K. Qi, J. Sankar, N. Huang and Y. Yun, Flow-Induced Corrosion of Absorbable Magnesium Alloy: In-situ and Real-time Electrochemical Study, Corros. Sci., 2016, 104, p 277–289.

    Article  CAS  Google Scholar 

  12. Y. Chen, Y. Song, S.X. Zhang, J.N. Li, C.L. Zhao and X.N. Zhang, Interaction Between a High Purity Magnesium Surface and PCL and PLA Coatings During Dynamic Degradation, Biomed. Mater., 2011, 6, p 025005.

    Article  Google Scholar 

  13. S.C. Garcea, Y. Wang and P.J. Withers, X-Ray Computed Tomography of Polymer Composites, Compos. Sci. Technol., 2018, 156, p 305–319.

    Article  CAS  Google Scholar 

  14. H. Yang, W. Wang, J. Shang, P. Wang, H. Lei, H. Chen and D. Fang, Segmentation of Computed Tomography Images and High-precision Reconstruction of Rubber Composite Structure Based on Deep Learning, Compos. Sci. Technol., 2021, 213, p 108875.

    Article  Google Scholar 

  15. M.H. Kang, H. Lee, T.S. Jang, Y.J. Seong, H.E. Kim, Y.H. Koh, J. Song and H.D. Jung, Biomimetic Porous Mg with Tunable Mechanical Properties and Biodegradation Rates for Bone Regeneration, Acta Biomater., 2019, 84, p 453–467.

    Article  CAS  Google Scholar 

  16. I. Ročňáková, E.B. Montufar, M. Horynová, T. Zikmund, K. Novotný, L. Klakurková, L. Čelko, G.L. Song and J. Kaiser, Assessment of Localized Corrosion Under Simulated Physiological Conditions of Magnesium Samples with Heterogeneous Microstructure: Value of x-Ray Computed Micro-Tomography Platform, Corros. Sci., 2016, 104, p 187–196.

    Article  Google Scholar 

  17. J.P. Kruth, M. Bartscher, S. Carmignato, R. Schmitt, L.D. Chiffre and A. Weckenmann, Computed Tomography for Dimensional Metrology, CIRP Ann. Manuf. Technol., 2011, 60, p 821–842.

    Article  Google Scholar 

  18. T.J. Marrow, M. Mostafavi, T. Hashimoto and G.E. Thompson, A Quantitative Three-Dimensional in situ Study of a Short Fatigue Crack in a Magnesium Alloy, Int. J. Fatigue, 2014, 66, p 183–193.

    Article  CAS  Google Scholar 

  19. M. Mostafavi, D.M. Collins, B. Cai, R. Bradley, R.C. Atwood, C. Reinhard, X. Jiang, M. Galano, P.D. Lee and T.J. Marrow, Yield Behavior Beneath Hardness Indentations in Ductile Metals, Measured by Three-Dimensional Computed x-Ray Tomography and Digital Volume Correlation, Acta Mater., 2015, 82, p 468–482.

    Article  CAS  Google Scholar 

  20. B. Liu, X. Hu, Y. Li, T. Xiao and F. Xu, Internal Three-Dimensional Strain Evolution of the Failure Process for Short Carbon Fiber Composite Through in situ Synchrotron Radiation x-Ray Computed Tomography, Carbon, 2020, 157, p 506–514.

    Article  CAS  Google Scholar 

  21. X.F. Hu, L.B. Wang, F. Xu, T.Q. Xiao and Z. Zhang, In situ Observations of Fractures in Short Carbon Fiber/Epoxy Composites, Carbon, 2014, 67, p 368–376.

    Article  CAS  Google Scholar 

  22. I. Hanhan, R. Agyei, X.H. Xiao and M.D. Sangid, Comparing Non-Destructive 3D x-Ray Computed Tomography with Destructive Optical Microscopy for Microstructural Characterization of Fiber Reinforced Composites, Compos. Sci. Technol., 2019, 184, p 107843.

    Article  CAS  Google Scholar 

  23. Y. Swolfs, H. Morton, A.E. Scott, L. Gorbatikh, P.A.S. Reed, I. Sinclair, S.M. Spearing and I. Verpoest, Synchrotron Radiation Computed Tomography for Experimental Validation of a Tensile Strength Model for Unidirectional Fibre-Reinforced Composites, Compos. Part A, 2015, 77, p 106–113.

    Article  CAS  Google Scholar 

  24. E. Schöberl, C. Breite, A. Melnikov, Y. Swolfs, M.N. Mavrogordato, I. Sinclair and S.M. Spearing, Fibre-Direction Strain Measurement in a Composite Ply Under Quasi-Static Tensile Loading Using Digital Volume Correlation and in situ Synchrotron Radiation Computed Tomography, Compos. Part A, 2020, 137, p 105935.

    Article  Google Scholar 

  25. P. Wang, J. Wen, H. Lei, B. Xu, Y. Liu, L. Yang and D. Fang, Morphology Characterization and in-situ Three-Dimensional Strain Field Monitor of Short Carbon Fiber-Reinforced Polymer Composites Under Tension, Compos. Struct., 2021, 262, p 113634.

    Article  CAS  Google Scholar 

  26. Y. Chai, Y. Wang, Z. Yousaf, N.T. Vo, T. Lowe, P. Potluri and P.J. Withers, Damage Evolution in Braided Composite Tubes under Torsion Studied by in-situ x-Ray Computed Tomography, Compos. Sci. Technol., 2020, 188, p 107976.

    Article  CAS  Google Scholar 

  27. C.L. Chu, X. Han, J. Bai, F. Xue and P.K. Chu, Fabrication and Degradation Behavior of Micro-Arc Oxidized Biomedical Magnesium Alloy Wires, Surf. Coat. Technol., 2012, 213, p 307–312.

    Article  CAS  Google Scholar 

  28. H. Cai, X. Li, F. Xue, C.L. Chu, C. Guo, J. Bai and X.B. Zhang, In Vitro Study on Cytocompatibility of Mg Wire/Poly(lactic acid) Composite Rods, J. Mater. Eng. Perform., 2021, 30, p 7214–7222.

    Article  CAS  Google Scholar 

  29. H. Cai, Y. Zhang, J. Meng, X. Li, F. Xue, C.L. Chu, L. Tao and J. Bai, Enhanced Fully-Biodegradable Mg/PLA Composite Rod: Effect of Surface Modification of Mg-2Zn Wire on the Interfacial Bonding, Surf. Coat. Technol., 2018, 350, p 722–731.

    Article  CAS  Google Scholar 

  30. H. Cai, J. Meng, X. Li, F. Xue, C.L. Chu, C. Guo and J. Bai, In Vitro Degradation Behavior of Mg wire/Poly(lactic acid) Composite Rods Prepared by Hot Pressing and Hot Drawing, Acta Biomater., 2019, 98, p 125–141.

    Article  CAS  Google Scholar 

  31. W. Ali, M.E. Rendon, A. Kopp, C. Gonzalez and J. LLorca, Strength, Corrosion Resistance and Cellular Response of Interfaces in Bioresorbable Poly-Lactic Acid/Mg Fiber Composites for Orthopedic Applications, J Mech. Behav. Biomed., 2021, 123, p 104781.

    Article  CAS  Google Scholar 

  32. L.E. Dresselhaus-Marais, G. Winther, M. Howard, A. Gonzalez, S.R. Breckling, C. Yildirim, P.K. Cook, M. Kutsal, H. Simons, C. Detlefs, J.H. Eggert and H.F. Poulsen, In Situ Visualization of Long Range Defect Interactions at the Edge of Melting, Sci. Adv., 2021, 7, p 8311.

    Article  Google Scholar 

  33. R.G. Kelly, J.S. Lee, Localized Corrosion: Crevice Corrosion, Encyclo. Inter. Chem. Surf. Sci. Electrochem., 2018, p 291–301.

  34. M. Deng, J. Zhou, G. Chen, D. Burkley, Y. Xu, D. Jamiolkowski and T. Barbolt, Effect of Load and Temperature on in Vitro Degradation of Poly(glycolide-co-l-lactide) Multifilament Braids, Biomaterials, 2005, 26, p 4327–4336.

    Article  CAS  Google Scholar 

  35. Z.K. Wu, S.C. Wu, J. Zhang, Z. Song, Y.N. Hu, G.Z. Kang and H.O. Zhang, Defect Induced Fatigue Behaviors of Selective Laser Melted Ti-6Al-4V via Synchrotron Radiation x-Ray Tomography, Acta Metall. Sin., 2019, 55, p 811–820.

    CAS  Google Scholar 

  36. C. Yu, S.C. Wu, Y.N. Hu, W.H. Zhang and Y.N. Fu, Three-Dimensional Imaging of Gas Pores in Fusion Welded Al Alloys by Synchrotron Radiation x-ray Microtomography, Acta Metall. Sin., 2015, 51, p 159–168.

    CAS  Google Scholar 

  37. H.L. Wu, C.J. Zhang, T.F. Lou, B.W. Chen, R.B. Yi, W.H. Wang, R.P. Zhang, M.C. Zuo, H.D. Xu, P. Han, S.X. Zhang, J.H. Ni and X.N. Zhang, Crevice Corrosion—A Newly Observed Mechanism of Degradation in Biomedical Magnesium, Acta Biomater., 2019, 98, p 152–159.

    Article  CAS  Google Scholar 

  38. B.W. Chen, H.L. Wu, R.B. Yi, W.H. Wang, H.D. Xu, S.X. Zhang, H.Z. Peng, J.W. Ma, H.M. Jiang, R. Zan, S. Qiao, Y. Sun, P. Hou, P. Han, J.H. Ni and X.N. Zhang, In Vitro Crevice Corrosion of Biodegradable Magnesium in Different Solutions, J. Mater. Sci. Technol., 2020, 52, p 83–88.

    Article  Google Scholar 

  39. R.C. Zeng, L.Y. Cui, K. Jiang, R. Liu, B.D. Zhao and Y.F. Zheng, In Vitro Corrosion and Cytocompatibility of a Microarc Oxidation Coating and Poly(L-lactic acid) Composite Coating on Mg-1Li-1Ca Alloy for Orthopedic Implants, ACS Appl. Mater. Inter., 2016, 8, p 10014–10028.

    Article  CAS  Google Scholar 

  40. R. Deblieck, B. Gerets, M. Boerakker, H. Caelers, A. Wilbers and T. Boonen, Relation between Life Time, Failure Stress and Craze Microstructure in Polyethylene as Evidenced by Fracture Surface Texture Analysis after An Accelerated Full-Notch Creep Test, Polymer, 2019, 176, p 264–273.

    Article  CAS  Google Scholar 

  41. H. Tsuji and K. Ikarashi, In Vitro Hydrolysis of Poly(L-lactide) Crystalline Residues as Extended-Chain Crystallites: III. Effects of pH and Enzyme, Polym. Degrad. Stabil., 2018, 85, p 647–656.

    Article  Google Scholar 

  42. W.F. Ng, K.Y. Chiu and F.T. Cheng, Effect of pH on the In Vitro Corrosion Rate of Magnesium Degradable Implant Material, Mater. Sci. Eng. C, 2010, 30, p 898–903.

    Article  CAS  Google Scholar 

  43. Y.F. Zheng, X.N. Gu and F. Witte, Biodegradable Metals, Mater. Sci. Eng. R, 2014, 77, p 1–34.

    Article  Google Scholar 

  44. G. Narayanan, V.N. Vernekar, E.L. Kuyinu and C.T. Laurencin, Poly(lactic acid)-Based Biomaterials for Orthopaedic Regenerative Engineering, Adv. Drug Deliver. Rev., 2016, 107, p 247–276.

    Article  CAS  Google Scholar 

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Acknowledgment

This work was jointly supported by National Natural Science Foundation of China (No. 51771054, No. 51971062), Science and Technology Project of Jiangsu Province (No. BE2019679), Introduction of Talent Research Fund in Nanjing Institute of Technology (YKJ202008, YKJ201704), Natural Science Foundation of Jiangsu Province (BK20181020) and Outstanding Scientific and Technological Innovation Team in Colleges and Universities of Jiangsu Province.

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Authors and Affiliations

  1. School of Materials Science and Engineering, Nanjing Institute of Technology, Nanjing, 211167, Jiangsu, China

    Hong Cai, Hongxing Wang, Ding Zhu, Xuan Li, Bing Han, Wentong Gao & Zusheng Hang

  2. Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology, Nanjing Institute of Technology, Nanjing, 211167, Jiangsu, China

    Hong Cai, Hongxing Wang, Ding Zhu, Xuan Li, Bing Han, Wentong Gao & Zusheng Hang

  3. School of Materials Science and Engineering, Southeast University, Jiangning, Nanjing, 211189, Jiangsu, China

    Feng Xue, Chenglin Chu & Jing Bai

  4. Jiangsu Key Laboratory for Advanced Metallic Materials, Jiangning, Nanjing, 211189, Jiangsu, China

    Feng Xue, Chenglin Chu & Jing Bai

  5. Institute of Biomedical Devices (Suzhou), Southeast University, Suzhou, 215163, Jiangsu, China

    Jing Bai

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  1. Hong Cai
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  2. Feng Xue
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Cai, H., Xue, F., Chu, C. et al. Internal Morphology Evolution of Mg Wire/Poly(Lactic Acid) Composites during Degradation Process Characterized by X-Ray Computed Tomography. J. of Materi Eng and Perform 31, 4507–4518 (2022). https://doi.org/10.1007/s11665-021-06555-w

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