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Risk Factors for Postoperative Complications Following Diverting Loop Ileostomy Takedown

  • Original Article
  • Published:
Journal of Gastrointestinal Surgery

Abstract

Introduction

Diverting loop ileostomies are frequently created to divert the fecal stream in an effort to protect downstream anastomoses. These are later reversed to restore intestinal continuity. The goal of this study is to evaluate risk factors for postoperative complications following diverting loop ileostomy takedown.

Materials and Methods

Patients who underwent diverting loop ileostomy takedown between January 1, 2010 and April 28, 2015 were identified in the Michigan Surgical Quality Collaborative registry. Candidate covariates were identified and a hierarchical logistic regression model was used to identify risk factors for postoperative complications.

Results

1,737 patients met the inclusion criteria. Rates of postoperative complications were generally low. Mean length of stay (LOS) was 5.6 (± 4.5) days. Outcomes of interest were the following: overall morbidity, serious morbidity, extended LOS, SSI, UTI, pneumonia, readmission, reoperation, and mortality. Risk factors for these outcomes included the following: ASA class, bleeding disorder, prolonged operative time, race, tobacco use, gender, steroid use, peripheral vascular disease, weight loss, and functional status.

Conclusions

Diverting loop ileostomy takedown has a complication rate of approximately 20%. Higher ASA class, longer operative times, history of bleeding disorder, and functional status were identified as risk factors for most complications.

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References

  1. Phatak UR, Kao LS, You YN, Rodriguez-Bigas MA, Skibber JM, Feig BW, et al. Impact of ileostomy-related complications on the multidisciplinary treatment of rectal cancer. Ann Surg Oncol. 2014;21(2):507–12.

    Article  PubMed  Google Scholar 

  2. Nurkin S, Kakarla VR, Ruiz DE, Cance WG, Tiszenkel HI. The role of faecal diversion in low rectal cancer: a review of 1791 patients having rectal resection with anastomosis for cancer, with and without a proximal stoma. Colorectal Dis. 2013;15(6):e309–16.

    Article  CAS  PubMed  Google Scholar 

  3. Man VC, Choi HK, Law WL, Foo DC. Morbidities after closure of ileostomy: analysis of risk factors. Int J Colorectal Dis. 2016;31(1):51–7.

    Article  PubMed  Google Scholar 

  4. Kaiser AM, Israelit S, Klaristenfeld D, Selvindoss P, Vukasin P, Ault G, et al. Morbidity of ostomy takedown. J Gastrointest Surg. 2008;12(3):437–41.

    Article  PubMed  Google Scholar 

  5. Mosdell DM, Doberneck RC. Morbidity and mortality of ostomy closure. Am J Surg. 1991;162(6):633–6; discussion 6-7.

    Article  CAS  PubMed  Google Scholar 

  6. Mansfield SD, Jensen C, Phair AS, Kelly OT, Kelly SB. Complications of loop ileostomy closure: a retrospective cohort analysis of 123 patients. World J Surg. 2008;32(9):2101–6.

    Article  CAS  PubMed  Google Scholar 

  7. Luglio G, Pendlimari R, Holubar SD, Cima RR, Nelson H. Loop ileostomy reversal after colon and rectal surgery: a single institutional 5-year experience in 944 patients. Arch Surg. 2011;146(10):1191–6.

    Article  PubMed  Google Scholar 

  8. Chiu A, Chan HT, Brown CJ, Raval MJ, Phang PT. Failing to reverse a diverting stoma after lower anterior resection of rectal cancer. Am J Surg. 2014;207(5):708–11; discussion 11.

    Article  PubMed  Google Scholar 

  9. Kye BH, Kim HJ, Kim JG, Cho HM. The nutritional impact of diverting stoma-related complications in elderly rectal cancer patients. Int J Colorectal Dis. 2013;28(10):1393–400.

    Article  PubMed  Google Scholar 

  10. Chun LJ, Haigh PI, Tam MS, Abbas MA. Defunctioning loop ileostomy for pelvic anastomoses: predictors of morbidity and nonclosure. Dis Colon Rectum. 2012;55(2):167–74.

    Article  PubMed  Google Scholar 

  11. Gessler B, Haglind E, Angenete E. A temporary loop ileostomy affects renal function. Int J Colorectal Dis. 2014;29(9):1131–5.

    Article  PubMed  Google Scholar 

  12. Bergquist JR, Thiels CA, Etzioni DA, Habermann EB, Cima RR. Failure of Colorectal Surgical Site Infection Predictive Models Applied to an Independent Dataset: Do They Add Value or Just Confusion? J Am Coll Surg. 2016;222(4):431–8.

  13. Chen M, Song X, Chen LZ, Lin ZD, Zhang XL. Comparing Mechanical Bowel Preparation With Both Oral and Systemic Antibiotics Versus Mechanical Bowel Preparation and Systemic Antibiotics Alone for the Prevention of Surgical Site Infection After Elective Colorectal Surgery: A Meta-Analysis of Randomized Controlled Clinical Trials. Dis Colon Rectum. 2016;59(1):70–8.

    Article  PubMed  Google Scholar 

  14. Scarborough JE, Mantyh CR, Sun Z, Migaly J. Combined mechanical and oral antibiotic bowel preparation reduces incisional surgical site infection and anastomotic leak rates after elective colorectal resection: an analysis of colectomy-targeted ACS NSQIP. Ann Surg. 2015;262(2):331–7.

    Article  PubMed  Google Scholar 

  15. Berenguer CM, Ochsner MG, Jr., Lord SA, Senkowski CK. Improving surgical site infections: using National Surgical Quality Improvement Program data to institute Surgical Care Improvement Project protocols in improving surgical outcomes. J Am Coll Surg. 2010;210(5):737–41, 41-3.

    Article  PubMed  Google Scholar 

  16. Lahat G, Tulchinsky H, Goldman G, Klauzner JM, Rabau M. Wound infection after ileostomy closure: a prospective randomized study comparing primary vs. delayed primary closure techniques. Tech Coloproctol. 2005;9(3):206–8.

    Article  CAS  PubMed  Google Scholar 

  17. Wick EC, Shore AD, Hirose K, Ibrahim AM, Gearhart SL, Efron J, et al. Readmission rates and cost following colorectal surgery. Dis Colon Rectum. 2011;54(12):1475–9.

    Article  PubMed  Google Scholar 

  18. Schneider EB, Hyder O, Brooke BS, Efron J, Cameron JL, Edil BH, et al. Patient readmission and mortality after colorectal surgery for colon cancer: impact of length of stay relative to other clinical factors. J Am Coll Surg. 2012;214(4):390–8; discussion 8-9.

    Article  PubMed  Google Scholar 

  19. Martin TD, Lorenz T, Ferraro J, Chagin K, Lampman RM, Emery KL, Zurkan JE, Boyd JL, Montgomergy K, Lang RE, Vandewarker JF, Cleary RK. Newly implemented enhanced recovery pathway positively impacts hospital length of stay. Surg Endosc. 2016;30(9):4014–28.

  20. Kerwel TG, Leichtle SW, Asgeirsson T, Hendren SK, Cleary RK, Luchtefeld MA. Risk factors for readmission after elective colectomy: postoperative complications are more important than patient and operative factors. Dis Colon Rectum. 2014;57(1):98–104.

    Article  PubMed  Google Scholar 

  21. Baraza W, Wild J, Barber W, Brown S. Postoperative management after loop ileostomy closure: are we keeping patients in hospital too long? Ann R Coll Surg Engl. 2010;92(1):51–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Shelygin YA, Chernyshov SV, Rybakov EG. Stapled ileostomy closure results in reduction of postoperative morbidity. Tech Coloproctol. 2010;14(1):19–23.

    Article  CAS  PubMed  Google Scholar 

  23. Saha AK, Tapping CR, Foley GT, Baker RP, Sagar PM, Burke DA, et al. Morbidity and mortality after closure of loop ileostomy. Colorectal Dis. 2009;11(8):866–71.

    Article  CAS  PubMed  Google Scholar 

  24. Williams LA, Sagar PM, Finan PJ, Burke D. The outcome of loop ileostomy closure: a prospective study. Colorectal Dis. 2008;10(5):460–4.

    Article  CAS  PubMed  Google Scholar 

  25. Perez RO, Habr-Gama A, Seid VE, Proscurshim I, Sousa AH, Jr., Kiss DR, et al. Loop ileostomy morbidity: timing of closure matters. Dis Colon Rectum. 2006;49(10):1539–45.

    Article  PubMed  Google Scholar 

  26. Wong KS, Remzi FH, Gorgun E, Arrigain S, Church JM, Preen M, et al. Loop ileostomy closure after restorative proctocolectomy: outcome in 1,504 patients. Dis Colon Rectum. 2005;48(2):243–50.

    Article  PubMed  Google Scholar 

  27. Mennigen R, Sewald W, Senninger N, Rijcken E. Morbidity of loop ileostomy closure after restorative proctocolectomy for ulcerative colitis and familial adenomatous polyposis: a systematic review. J Gastrointest Surg. 2014;18(12):2192–200.

    Article  PubMed  Google Scholar 

  28. D’Haeninck A, Wolthuis AM, Penninckx F, D’Hondt M, D’Hoore A. Morbidity after closure of a defunctioning loop ileostomy. Acta Chir Belg. 2011;111(3):136–41.

    Article  PubMed  Google Scholar 

  29. Poskus E, Kildusis E, Smolskas E, Ambrazevicius M, Strupas K. Complications after loop ileostomy closure: a retrospective analysis of 132 patients. Viszeralmedizin. 2014;30(4):276–80.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Rubio-Perez I, Leon M, Pastor D, Diaz Dominguez J, Cantero R. Increased postoperative complications after protective ileostomy closure delay: An institutional study. World J Gastrointest Surg. 2014;6(9):169–74.

    Article  PubMed  PubMed Central  Google Scholar 

  31. van der Valk ME, Mangen MJ, Severs M, van der Have M, Dijkstra G, van Bodegraven AA, et al. Comparison of costs and quality of life in ulcerative colitis patients with an ileal pouch-anal anastomosis, ileostomy and anti-TNFalpha Therapy. J Crohns Colitis. 2015;9(11):1016–23.

    Article  PubMed  Google Scholar 

  32. Sier MF, van Gelder L, Ubbink DT, Bemelman WA, Oostenbroek RJ. Factors affecting timing of closure and non-reversal of temporary ileostomies. Int J Colorectal Dis. 2015;30(9):1185–92.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  33. Lewis P, Bartolo DC. Closure of loop ileostomy after restorative proctocolectomy. Ann R Coll Surg Engl. 1990;72(4):263–5.

    CAS  PubMed  PubMed Central  Google Scholar 

  34. Sharma A, Deeb AP, Rickles AS, Iannuzzi JC, Monson JR, Fleming FJ. Closure of defunctioning loop ileostomy is associated with considerable morbidity. Colorectal Dis. 2013;15(4):458–62.

    Article  CAS  PubMed  Google Scholar 

  35. Mokart D, Giaoui E, Barbier L, Lambert J, Sannini A, Chow-Chine L, et al. Postoperative sepsis in cancer patients undergoing major elective digestive surgery is associated with increased long-term mortality. J Crit Care. 2016;31(1):48–53.

    Article  PubMed  Google Scholar 

  36. Fazio VW, Kiran RP, Remzi FH, Coffey JC, Heneghan HM, Kirat HT, et al. Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients. Ann Surg. 2013;257(4):679–85.

    Article  PubMed  Google Scholar 

  37. Geltzeiler CB, Rotramel A, Wilson C, Deng L, Whiteford MH, Frankhouse J. Prospective study of colorectal enhanced recovery after surgery in a community hospital. JAMA Surg. 2014;149(9):955–61.

    Article  PubMed  Google Scholar 

  38. Greco M, Capretti G, Beretta L, Gemma M, Pecorelli N, Braga M. Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials. World J Surg. 2014;38(6):1531–41.

    Article  PubMed  Google Scholar 

  39. Adamina M, Kehlet H, Tomlinson GA, Senagore AJ, Delaney CP. Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery. Surgery. 2011;149(6):830–40.

    Article  PubMed  Google Scholar 

  40. Lawrence JK, Keller DS, Samia H, Ermlich B, Brady KM, Nobel T, et al. Discharge within 24 to 72 hours of colorectal surgery is associated with low readmission rates when using Enhanced Recovery Pathways. J Am Coll Surg. 2013;216(3):390–4.

    Article  PubMed  Google Scholar 

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Correspondence to Anuradha R. Bhama.

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The St. Joseph Mercy Health System Institutional Review Board approval was obtained for this study.

Additional information

Previous Communication: Presented as a podium presentation at the American Society of Colon and Rectal Surgeons Annual Scientific Meeting, April 30 – May 4, 2016, Los Angeles, California

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Bhama, A.R., Batool, F., Collins, S.D. et al. Risk Factors for Postoperative Complications Following Diverting Loop Ileostomy Takedown. J Gastrointest Surg 21, 2048–2055 (2017). https://doi.org/10.1007/s11605-017-3567-y

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  • DOI: https://doi.org/10.1007/s11605-017-3567-y

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