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Advances in polymer-based detection of environmental ibuprofen in wastewater

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Abstract

Globally, ibuprofen is the third most consumed drug and its presence in the environment is a concern because little is known about its adverse effects on humans and aquatic life. Environmentalists have made monitoring and the detection of ibuprofen in biological and environmental matrices a priority. For the detection and monitoring of ibuprofen, sensors and biosensors have provided rapid analysis time, sensitivity, high-throughput screening, and real-time analysis. Researchers are increasingly seeking eco-friendly technology, and this has led to an interest in developing biodegradable, bioavailable, and non-toxic sensors, or biosensors. The integration of polymers into sensor systems has proven to significantly improve sensitivity, selectivity, and stability and minimize sample preparation using bioavailable and biodegradable polymers. This review provides a general overview of perspectives and trends of polymer-based sensors and biosensors for the detection of ibuprofen compared to non-polymer-based sensors.

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The datasets used and/or analyzed during the current study are available on request from the corresponding authors on reasonable request.

References

  • Adham S, Dores R, Hussain A, Katebah M (2012) Using advanced water treatment technologies to treat produced water from the petroleum industry. In SPE International Production and Operations Conference & Exhibition. OnePetro

  • Ahad IZ, Harun SW, Gan SN, Phang SW (2018) Effect of polymerization temperatures on polyaniline coated fiber Bragg grating sensor for chloroform detection. In Macromolecular Symposia 382(1):1800088

    Article  Google Scholar 

  • Ahmed N, Kausar A, Muhammad B (2016) Shape memory properties of electrically conductive multi-walled carbon nanotube-filled polyurethane/modified polystyrene blends. J Plast Film Sheeting 32(3):272–292

    Article  CAS  Google Scholar 

  • Alqarni SA, Hussein MA, Ganash AA, Khan A (2020) Composite material–based conducting polymers for electrochemical sensor applications: a mini review. BioNanoScience 10(1):351–364

    Article  Google Scholar 

  • Al-Rekabi WS, Qiang H, Qiang WW (2007) Improvements in wastewater treatment technology. Pak J Nutr 6(2):104–110

    Article  Google Scholar 

  • Amin S, Soomro MT, Memon N, Solangi AR, Qureshi T, Behzad AR (2014) Disposable screen printed graphite electrode for the direct electrochemical determination of ibuprofen in surface water. Environ Nanotechnol Monit Manag 1:8–13

    Google Scholar 

  • Andreozzi R, Caprio V, Insola A, Marotta R (1999) Advanced oxidation processes (AOP) for water purification and recovery. Catal Today 53(1):51–59

    Article  CAS  Google Scholar 

  • Apetrei IM, Rodriguez-Mendez ML, Apetrei C, De Saja JA (2013) Enzyme sensor based on carbon nanotujbes/cobalt (II) phthalocyanine and tyrosinase used in pharmaceutical analysis. Sens Actuators, B Chem 177:138–144

    Article  CAS  Google Scholar 

  • Aragay G, Pino F, Merkoçi A (2012) Nanomaterials for sensing and destroying pesticides. Chem Rev 112(10):5317–5338

    Article  CAS  Google Scholar 

  • Araujo L, Troconis ME, Espina MB, Prieto A (2014) Persistence of ibuprofen, ketoprofen, diclofenac and clofibric acid in natural waters. J Environ Human 1(2):32–38

    Article  Google Scholar 

  • Arduini F, Cinti S, Scognamiglio V, Moscone D (2020) Nanomaterial-based sensors. In Handbook of Nanomaterials in Analytical Chemistry. Elsevier. pp. 329–359

  • Arenas MC, Sánchez G, Nicho ME, Elizalde-Torres J, Castaño VM (2012) Engineered doped and codoped polyaniline gas sensors synthesized in N, N, dimethylformamide media. Appl Phys A 106(4):901–908

    Article  CAS  Google Scholar 

  • Arora K, Prabhakar N, Chand S, Malhotra BD (2007) E scherichia coli genosensor based on polyaniline. Anal Chem 79(16):6152–6158

    Article  CAS  Google Scholar 

  • Arulraj AD, Sundaram E, Vasantha VS, Neppolian B (2018) Polypyrrole with a functionalized multi-walled carbon nanotube hybrid nanocomposite: a new and efficient nitrite sensor. New J Chem 42(5):3748–3757

    Article  CAS  Google Scholar 

  • Ates M (2013) A review study of (bio) sensor systems based on conducting polymers. Mater Sci Eng, C 33(4):1853–1859

    Article  CAS  Google Scholar 

  • Attia MS, Ramis MN, Khalil LH, Hashem SG (2012) Spectrofluorimetric assessment of chlorzoxazone and ibuprofen in pharmaceutical formulations by using Eu-tetracycline HCl optical sensor doped in sol-gel matrix. J Fluoresc 22(2):779–788

    Article  CAS  Google Scholar 

  • Aulestia M, Flores A, Mangas EL, Pérez-Pulido AJ, Santero E, Camacho EM (2021) Isolation and genomic characterization of the ibuprofen-degrading bacterium Sphingomonas strain MPO218. Environ Microbiol 23(1):267–280

    Article  CAS  Google Scholar 

  • Babudri F, Farinola GM, Naso F (2004) Synthesis of conjugated oligomers and polymers: the organometallic way. J Mater Chem 14(1):11–34

    Article  CAS  Google Scholar 

  • Bitinis N, Hernández M, Verdejo R, Kenny JM, Lopez-Manchado MA (2011) Recent advances in clay/polymer nanocomposites. Adv Mater 23(44):5229–5236

    Article  CAS  Google Scholar 

  • Boonchoo P, Rempel GL, Prasassarakich P (2014) Synthesis of polyisoprene–montmorillonite nanocomposites via differential microemulsion polymerization and application of PIP–Mt in natural rubber. Appl Clay Sci 88:186–193

    Article  Google Scholar 

  • Braz FS, Silva MR, Silva FS, Andrade SJ, Fonseca AL, Kondo MM (2014) Photocatalytic degradation of ibuprofen using TiO 2 and ecotoxicological assessment of degradation intermediates against Daphnia similis. Journal of Environmental Protection, 2014

  • Cai J, Sun B, Gou X, Gou Y, Li W, Hu F (2018) A novel way for analysis of calycosin via polyaniline functionalized graphene quantum dots fabricated electrochemical sensor. J Electroanal Chem 816:123–131

    Article  CAS  Google Scholar 

  • Cai Z, Martin CR (1989) Electronically conductive polymer fibers with mesoscopic diameters show enhanced electronic conductivities. J Am Chem Soc 111(11):4138–4139

    Article  CAS  Google Scholar 

  • Cardenas JR, De França MGO, De Vasconcelos EA, De Azevedo WM, Da Silva EF (2007) Growth of sub-micron fibres of pure polyaniline using the electrospinning technique. J Phys D Appl Phys 40(4):1068

    Article  CAS  Google Scholar 

  • Caviglioli G, Valeria P, Brunella P, Sergio C, Attilia A, Gaetano B (2002) Identification of degradation products of ibuprofen arising from oxidative and thermal treatments. J Pharm Biomed Anal 30(3):499–509

    Article  CAS  Google Scholar 

  • Chianese S, Iovino P, Canzano S, Prisciandaro M, Musmarra D (2016) Ibuprofen degradation in aqueous solution by using UV light. Desalin Water Treat 57(48):22878–22886

    Article  CAS  Google Scholar 

  • Cho IH, Lee J, Kim J, Kang MS, Paik JK, Ku S, Cho HM, Irudayaraj J, Kim DH (2018) Current technologies of electrochemical immunosensors: perspective on signal amplification. Sensors 18(1):207

    Article  Google Scholar 

  • Chopra S, Kumar D (2020) Ibuprofen as an emerging organic contaminant in environment, distribution and remediation. Heliyon 6(6):e04087

    Article  Google Scholar 

  • Clementino FC, Peixoto VG, de Araújo DT, Ciuffi KJ, Nassar EJ, Vicente MA, de Faria EH (2022) Detection of Cr (III), prometryn, and ibuprofen by hybrid Eu (III)–dipicolinate kaolinite luminescent sensor. Appl Clay Sci 227:106591

    Article  CAS  Google Scholar 

  • Cole E (2014). The effects of tetracycline and ibuprofen on common duckweed, Lemna minor L.ESSAI, 12:1, 13

  • Coleman RJ, Lawrie G, Lambert LK, Whittaker M, Jack KS, Grøndahl L (2011) Phosphorylation of alginate: synthesis, characterization, and evaluation of in vitro mineralization capacity. Biomacromol 12(4):889–897

    Article  CAS  Google Scholar 

  • Daughton CG, Ternes TA (1999) Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ Health Perspect 107:907–938

    Article  CAS  Google Scholar 

  • de Oliveira AD, Beatrice CAG (2018) Polymer nanocomposites with different types of nanofiller. Nanocomposites-Recent Evolutions, 103–104

  • Dhand C, Dwivedi N, Mishra S, Solanki PR, Mayandi V, Beuerman RW, Malhotra BD (2015) Polyaniline-based biosensors. Nanobiosensors in disease diagnosis, 4, 25

  • Ding Y, Li X, Guo Y, Yan J, Ling J, Li W, Zha L (2017) Rapid and sensitive detection of ketamine in blood using novel fluorescence genosensor. Anal Bioanal Chem 409(30):7027–7034

    Article  CAS  Google Scholar 

  • Dondo N, Shumba M, Moyo M, Nyoni S (2020) Simultaneous non-steroidal anti-inflammatory drug electrodetection on nitrogen doped carbon nanodots and nanosized cobalt phthallocyanine conjugate modified glassy carbon electrode. Arab J Chem 13(11):7809–7819

    Article  CAS  Google Scholar 

  • Eisazadeh H (1994) Design and production of novel conducting polymer colloids

  • El Harrad L, Bourais I, Mohammadi H, Amine A (2018) Recent advances in electrochemical biosensors based on enzyme inhibition for clinical and pharmaceutical applications. Sensors 18(1):164

    Article  Google Scholar 

  • Eslami MR, Alizadeh N (2015) A dual usage smart sorbent/recognition element based on nanostructured conducting molecularly imprinted polypyrrole for simultaneous potential-induced nanoextraction/determination of ibuprofen in biomedical samples by quartz crystal microbalance sensor. Sens Actuators, B Chem 220:880–887

    Article  CAS  Google Scholar 

  • Faisal M, Harraz FA, Jalalah M, Alsaiari M, Al-Sayari SA, Al-Assiri MS (2020) Polythiophene doped ZnO nanostructures synthesized by modified sol-gel and oxidative polymerization for efficient photodegradation of methylene blue and gemifloxacin antibiotic. Mater Today Commun 24:101048

    Article  CAS  Google Scholar 

  • Faridbod F, Gupta, VK, Zamani HA (2011) Electrochemical sensors and biosensors. International Journal of Electrochemistry, 1–2

  • Finny AS, Cheng N, Andreescu S (2022) Advances in biosensing technology in the pharmaceutical industry. Biosensing and Micro-Nano Devices, 243–263

  • Flippin JL, Huggett DM, Foran CM (2007) Changes in the timing of reproduction following chronic exposure to ibuprofen in Japanese medaka. Oryzias Latipes Aquatic Toxicol 81(1):73–78

    Article  CAS  Google Scholar 

  • Ghadimi H, Tehrani RM, Basirun WJ, Aziz-NJ Ab, Mohamed N, Ab Ghani S (2016) Electrochemical determination of aspirin and caffeine at MWCNTs-poly-4-vinylpyridine composite modified electrode. J Taiwan Inst Chem Eng 65:101–109

    Article  CAS  Google Scholar 

  • Góngora JF, Elizondo P, Hernández-Ramírez A (2017) Photocatalytic degradation of ibuprofen using TiO 2 sensitized by Ru (II) polyaza complexes. Photochem Photobiol Sci 16(1):31–37

    Article  Google Scholar 

  • Gonzalez-Rey M, Bebianno MJ (2012) Does non-steroidal anti-inflammatory (NSAID) ibuprofen induce antioxidant stress and endocrine disruption in mussel Mytilus galloprovincialis? Environ Toxicol Pharmacol 33(2):361–371

    Article  CAS  Google Scholar 

  • Granot E, Basnar B, Cheglakov Z, Katz E, Willner I (2006) Enhanced bioelectrocatalysis using single-walled carbon nanotubes (SWCNTs)/polyaniline hybrid systems in thin-film and microrod structures associated with electrodes. Electroanalysis: An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis, 18:1, 26–34

  • Hackett AJ, Malmström J, Travas-Sejdic J (2017) Functionalization of conducting polymers for biointerface applications. Prog Polym Sci 70:18–33

    Article  CAS  Google Scholar 

  • Han S, Choi K, Kim J, Ji K, Kim S, Ahn B, Giesy JP (2010) Endocrine disruption and consequences of chronic exposure to ibuprofen in Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa. Aquat Toxicol 98(3):256–264

    Article  CAS  Google Scholar 

  • Haseler M, Balciunas A, Hauk R, Sabaliauskaite V, Chubarenko I, Ershova A, Schernewski G (2020) Marine litter pollution in Baltic Sea beaches–application of the sand rake method. Front Environ Sci 8:238

    Article  Google Scholar 

  • He G, Pan Q, Rempel GL (2003) Synthesis of poly(methyl methacrylate) nanosize particles by differential microemulsion polymerization. Macromol Rapid Commun 24:585–588

    Article  CAS  Google Scholar 

  • Huang H, Liu G, Yao K, Kang Y, Li F, Lin L (2015) Ozone-oxidation products of ibuprofen and toxicity analysis in simulated drinking water. J Drug Metab Toxicol 6(3):1

    Article  Google Scholar 

  • Idil N, Mattiasson B (2017) Imprinting of microorganisms for biosensor application. Sensors 17:1–15

    Article  Google Scholar 

  • Istakova OI, Konev DV, Glazkov AT, Medvedeva TO, Zolotukhina EV, Vorotyntsev MA (2019) Electrochemical synthesis of polypyrrole in powder form. J Solid State Electrochem 23(1):251–258

    Article  CAS  Google Scholar 

  • Jang J, Yoon H (2005) Formation mechanism of conducting polypyrrole nanotubes in reverse micelle systems. Langmuir 21(24):11484–11489

    Article  CAS  Google Scholar 

  • Jang J, Oh JH, Stucky GD (2002) Fabrication of ultrafine conducting polymer and graphite nanoparticles. Angew Chem Int Ed 41(21):4016–4019

    Article  CAS  Google Scholar 

  • Jia Y, Khanal SK, Yin L, Sun L, Lu H (2021) Influence of ibuprofen and its biotransformation products on different biological sludge systems and ecosystem. Environ Int 146:106265

    Article  CAS  Google Scholar 

  • Jiang Z, Feng B, Xu J, Zhang P, Qing Z (2020) Graphene biosensors for bacterial and viral pathogens. Biosens Bioelectron 166:1–19

    Article  Google Scholar 

  • Jurado A, Vàzquez-Suñé E, Carrera J, de Alda ML, Pujades E, Barceló D (2012) Emerging organic contaminants in groundwater in Spain: a review of sources, recent occurrence and fate in a European context. Sci Total Environ 440:82–94

    Article  CAS  Google Scholar 

  • Kang TS, Lee SW, Joo J, Lee JY (2005) Electrically conducting polypyrrole fibers spun by electrospinning. Synth Met 153(1):61–64

    Article  CAS  Google Scholar 

  • Kapishon V, Whitney RA, Champagne P, Cunningham MF, Neufeld RJ (2015) Polymerization induced self-assembly of alginate based amphiphilic graft copolymers synthesized by single electron transfer living radical polymerization. Biomacromol 16(7):2040–2048

    Article  CAS  Google Scholar 

  • Karaseva NA, Pluhar B, Beliaeva EA, Ermolaeva TN, Mizaikoff B (2019) Synthesis and application of molecularly imprinted polymers for trypsin piezoelectric sensors. Sens Actuators, B Chem 280:272–279

    Article  CAS  Google Scholar 

  • Kaur G, Kaur A, Kaur H (2021) Review on nanomaterials/conducting polymer based nanocomposites for the development of biosensors and electrochemical sensors. Polymer-Plastics Technol Mater 60(5):502–519

    CAS  Google Scholar 

  • Kausar A (2020) Polyaniline and quantum dot-based nanostructures: developments and perspectives. J Plast Film Sheeting 36(4):430–447

    Article  CAS  Google Scholar 

  • Kausar A, Meer S, Iqbal T (2017) Structure, morphology, thermal, and electro-magnetic shielding properties of polystyrene microsphere/polyaniline/multi-walled carbon nanotube nanocomposite. J Plast Film Sheeting 33(3):262–289

    Article  CAS  Google Scholar 

  • Khizar S, Zine N, Jaffrezic-Renault N, Elaissari A (2022) Prospective analytical role of sensors for environmental screening and monitoring. TrAC Trends in Analytical Chemistry, 116751

  • Khokhar D, Jadoun S, Arif R, Jabin S (2021) Functionalization of conducting polymers and their applications in optoelectronics. Polymer-Plastics Technol Mater 60(5):463–485

    CAS  Google Scholar 

  • Kiebooms R, Menon R, Lee K (2001) Synthesis, electrical, and optical properties of conjugated polymers. In Handbook of advanced electronic and photonic materials and devices. Academic Press. 1–100

  • Kim M, Guerra P, Shah A, Parsa M, Alaee M, Smyth SA (2014) Removal of pharmaceuticals and personal care products in a membrane bioreactor wastewater treatment plant. Water Sci Technol 69(11):2221–2229

    Article  CAS  Google Scholar 

  • Kim YJ, Kim YS, Niazi JH, Gu MB (2010a) Electrochemical aptasensor for tetracycline detection. Bioprocess Biosyst Eng 33(1):31–37

    Article  CAS  Google Scholar 

  • Kim YS, Hyun CJ, Kim IA, Gu MB (2010b) Isolation and characterization of enantioselective DNA aptamers for ibuprofen. Bioorg Med Chem 18(10):3467–3473

    Article  CAS  Google Scholar 

  • Kim SD, Cho J, Kim IS, Vanderford BJ, Snyder SA (2007) Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters. Water Res 41(5):1013–1021

    Article  CAS  Google Scholar 

  • Kline RJ, McGehee MD, Kadnikova EN, Liu J, Fréchet JM, Toney MF (2005) Dependence of regioregular poly (3-hexylthiophene) film morphology and field-effect mobility on molecular weight. Macromolecules 38(8):3312–3319

    Article  CAS  Google Scholar 

  • Koinkar PM, Patil SS, Moriga T, More MA (2016) Electrochemical synthesis of conducting polypyrrole film on tin substrate: structural, chemical and field emission investigations. J Nano Res Trans Tech Publications Ltd 36:44–50

    CAS  Google Scholar 

  • Kuchmenko TA, Kozhukhova AV, Orobinskii YI (2008) Procedure for the analysis of sedative drugs with the use of an array of piezoelectric sensors (exemplified in the determination of the drug Corvalol). J Anal Chem 63(3):285–291

    Article  CAS  Google Scholar 

  • Kumar A, Rana A, Sharma G, Naushad M, Dhiman P, Kumari A, Stadler FJ (2019) Recent advances in nano-Fenton catalytic degradation of emerging pharmaceutical contaminants. J Mol Liq 290:111177

    Article  CAS  Google Scholar 

  • Lagashetty A, Venkataraman A (2005) Polymer nanocomposites. Resonance 10(7):49–57

    Article  CAS  Google Scholar 

  • Le TH, Kim Y, Yoon H (2017) Electrical and electrochemical properties of conducting polymers. Polymers 9(4):150

    Article  Google Scholar 

  • Lenik J (2016) Fabrication of a developed potentiometric ibuprofen electrode based on new functionalized beta -cyclodextrins for pharmaceuticals determination. IEEE Sens J 17(5):1215–1221

    Article  Google Scholar 

  • Lenik J, Nieszporek J (2018) Construction of a glassy carbon ibuprofen electrode modified with multi-walled carbon nanotubes and cyclodextrins. Sens Actuators, B Chem 255:2282–2289

    Article  CAS  Google Scholar 

  • Lenik J, Wardak C (2013) Studies on influence of (2-hydroxypropyl)-beta-cyclodextrin on properties of a new indomethacin electrode. IEEE Sens J 13(12):4638–4647

    Article  CAS  Google Scholar 

  • Li S, Chen S, Zhuo B, Li Q, Liu W, Guo X (2017) Flexible ammonia sensor based on PEDOT: PSS/silver nanowire composite film for meat freshness monitoring. IEEE Electron Device Lett 38(7):975–978

    Article  CAS  Google Scholar 

  • Li S, Ge W, Suryoprabowo S, Liu J, Kuang H, Zhu J, Xu C (2021) A paper-based sensor for rapid and ultrasensitive detection of ibuprofen in water and herbal tea. Analyst 146(22):6874–6882

    Article  CAS  Google Scholar 

  • Li ZF, Blum FD, Bertino MF, Kim CS (2012) Amplified response and enhanced selectivity of metal-PANI fiber composite based vapor sensors. Sens Actuators, B Chem 161(1):390–395

    Article  CAS  Google Scholar 

  • Li ZF, Blum FD, Bertino MF, Kim CS, Pillalamarri SK (2008) One-step fabrication of a polyaniline nanofiber vapor sensor. Sens Actuators, B Chem 134(1):31–35

    Article  CAS  Google Scholar 

  • Licona KPM, Geaquinto LDO, Nicolini JV, Figueiredo NG, Chiapetta SC, Habert AC, Yokoyama L (2018) Assessing potential of nanofiltration and reverse osmosis for removal of toxic pharmaceuticals from water. J Water Process Eng 25:195–204

    Article  Google Scholar 

  • Lima HRS, da Silva JS, de Oliveira Farias EA, Teixeira PRS, Eiras C, Nunes LCC (2018) Electrochemical sensors and biosensors for the analysis of antineoplastic drugs. Biosens Bioelectron 108:27–37

    Article  CAS  Google Scholar 

  • Lishman L, Smyth SA, Sarafin K, Kleywegt S, Toito J, Peart T, Seto P (2006) Occurrence and reductions of pharmaceuticals and personal care products and estrogens by municipal wastewater treatment plants in Ontario Canada. Sci Total Environ 367(2):544–558

    Article  CAS  Google Scholar 

  • Liu A, Jiang L, Liu F, Zhao L, Wang J, Lu G (2021) The gas sensor utilizing polyaniline/MoS2 nanosheets/SnO2 nanotubes for the room temperature detection of ammonia. Sens Actuators, B Chem 332:129444

    Article  CAS  Google Scholar 

  • Liu G, Lin Y (2007) Nanomaterial labels in electrochemical immunosensors and immunoassays. Talanta 74(3):308–317

    Article  CAS  Google Scholar 

  • Liu Y, Feng X, Shen J, Zhu JJ, Hou W (2008) Fabrication of a novel glucose biosensor based on a highly electroactive polystyrene/polyaniline/Au nanocomposite. J Phys Chem B 11(30):9237–9242

    Article  Google Scholar 

  • Loffredo F, Burrasca G, Quercia L, Sala DD (2007) Gas sensor devices obtained by ink-jet printing of polyaniline suspensions. Macromol Symposia Weinheim: WILEY-VCH Verlag 247(1):357–436

    Article  CAS  Google Scholar 

  • Loftsson T, Duchêne D (2007) Cyclodextrins and their pharmaceutical applications. Int J Pharm 329(1):1–11

    Article  CAS  Google Scholar 

  • Long Y, Li W, Nie L, Yao S (2001) Ion-selective piezoelectric sensor for niacinamide assay in serum and urine. J Pharm Biomed Anal 24(3):361–369

    Article  CAS  Google Scholar 

  • Luo Y, Guo W, Ngo HH, Nghiem LD, Hai FI, Zhang J, Wang XC (2014) A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment. Sci Total Environ 473:619–641

    Article  Google Scholar 

  • MacDiarmid AG, Jones WE Jr, Norris ID, Gao J, Johnson AT Jr, Pinto NJ, Llaguno M (2001) Electrostatically-generated nanofibers of electronic polymers. Synth Met 119(1):27–30

    Article  CAS  Google Scholar 

  • Madikizela LM, Chimuka L (2017) Occurrence of naproxen, ibuprofen, and diclofenac residues in wastewater and river water of KwaZulu-Natal Province in South Africa. Environ Monit Assess 189(7):1–12

    Article  CAS  Google Scholar 

  • Maduraiveeran G, Sasidharan M, Ganesan V (2018) Electrochemical sensor and biosensor platforms based on advanced nanomaterials for biological and biomedical applications. Biosens Bioelectron 103:113–129

    Article  CAS  Google Scholar 

  • Malaeb L, Ayoub GM (2011) Reverse osmosis technology for water treatment: state of the art review. Desalination 267(1):1–8

    Article  CAS  Google Scholar 

  • Manea F, Motoc S, Pop A, Remes A, Schoonman J (2012) Silver-functionalized carbon nanofiber composite electrodes for ibuprofen detection. Nanoscale Res Lett 7(1):1–4

    Article  Google Scholar 

  • Marcos-Hernández M, Villagrán D (2019) Mesoporous composite nanomaterials for dye removal and other applications. In Composite Nanoadsorbents, Elsevier, 265-293

  • McCullough RD (1998) The chemistry of conducting polythiophenes. Adv Mater 10(2):93–116

    Article  CAS  Google Scholar 

  • Mekassa B, Tessema M, Chandravanshi BS, Tefera M (2017) Square wave voltammetric determination of ibuprofen at poly (l-aspartic acid) modified glassy carbon electrode. IEEE Sens J 18(1):37–44

    Article  Google Scholar 

  • Mendez-Arriaga F, Almanza R (2014) Water remediation by UV–vis/H2O2 process, photo-Fenton-like oxidation, and zeolite ZSM5. Desalin Water Treat 52(31):5822–5832

    Article  CAS  Google Scholar 

  • Micari M, Giacalone F, Cipollina A, Micale G, Tamburini A (2022). Reverse electrodialysis heat engine (REDHE). In Salinity Gradient Heat Engines. Woodhead Publishing, 127–162

  • Misra SCK, Mathur P, Srivastava BK (2004) Vacuum-deposited nanocrystalline polyaniline thin film sensors for detection of carbon monoxide. Sens Actuators, A 114(1):30–35

    Article  CAS  Google Scholar 

  • Miyata S (1997) Organic electroluminescent materials and devices. CRC Press

    Google Scholar 

  • Mondal S, Wickramasinghe SR (2008) Produced water treatment by nanofiltration and reverse osmosis membranes. J Membr Sci 322(1):162–170

    Article  CAS  Google Scholar 

  • Mostafavi M, Yaftian MR, Piri F, Shayani-Jam H (2018) A new diclofenac molecularly imprinted electrochemical sensor based upon a polyaniline/reduced graphene oxide nano-composite. Biosens Bioelectron 122:160–167

    Article  CAS  Google Scholar 

  • Motoc S, Remes A, Pop A, Manea F, Schoonman J (2013) Electrochemical detection and degradation of ibuprofen from water on multi-walled carbon nanotubes-epoxy composite electrode. J Environ Sci 25(4):838–847

    Article  CAS  Google Scholar 

  • Müller K, Bugnicourt E, Latorre M, Jorda M, Echegoyen Sanz Y, Lagaron JM, Schmid M et al (2017) Review on the processing and properties of polymer nanocomposites and nanocoatings and their applications in the packaging, automotive and solar energy fields. Nanomaterials 7(4):74

    Article  Google Scholar 

  • Nagaraj VJ, Jacobs M, Vattipalli KM, Annam VP, Prasad S (2014) Nanochannel-based electrochemical sensor for the detection of pharmaceutical contaminants in water. Environ Sci Process Impacts 16(1):135–140

    Article  CAS  Google Scholar 

  • Nair AS, Sooraj MP (2020) Molecular imprinted polymer-wrapped AgNPs-decorated acid-functionalized graphene oxide as a potent electrochemical sensor for ibuprofen. J Mater Sci 55(8):3700–3711

    Article  CAS  Google Scholar 

  • Namsheer K, Rout CS (2021) Conducting polymers: a comprehensive review on recent advances in synthesis, properties and applications. RSC Adv 11(10):5659–5697

    Article  Google Scholar 

  • Ngqwala NP, Muchesa P (2020) Occurrence of pharmaceuticals in aquatic environments: a review and potential impacts in South Africa. S Afr J Sci 116(7):1–7

    Google Scholar 

  • Niu Z, Yang Z, Hu Z, Lu Y, Han CC (2003) Polyaniline–silica composite conductive capsules and hollow spheres. Adv Func Mater 13(12):949–954

    Article  CAS  Google Scholar 

  • Ogunwole GA, Saliu JK., Osuala FI, Odunjo FO (2021) Chronic levels of ibuprofen induces haematoxic and histopathology damage in the gills, liver, and kidney of the African sharptooth catfish (Clarias gariepinus). Environmental Science and Pollution Research, 1–11

  • Oh WK, Kwon OS, Jang J (2013) Conducting polymer nanomaterials for biomedical applications: cellular interfacing and biosensing. Polym Rev 53(3):407–442

    Article  CAS  Google Scholar 

  • Pahurkar VG, Tamgadge YS, Gambhire AB, Muley GG (2015) Evanescent wave absorption based polyaniline cladding modified fiber optic intrinsic biosensor for glucose sensing application. Measurement 61:9–15

    Article  Google Scholar 

  • Pan L, Qiu H, Dou C, Li Y, Pu L, Xu J, Shi Y (2010) Conducting polymer nanostructures: template synthesis and applications in energy storage. Int J Mol Sci 11(7):2636–2657

    Article  CAS  Google Scholar 

  • Park CS, Kim DH, Shin BJ, Kim DY, Lee HK, Tae HS (2016) Conductive polymer synthesis with single crystallinity via a novel plasma polymerization technique for gas sensor applications. Materials 9(10):812

    Article  Google Scholar 

  • Patel M, Kumar R, Kishor K, Mlsna T, Pittman CU, Mohan D (2019) Pharmaceuticals of emerging concern in aquatic systems: chemistry, occurrence, effects, and removal methods. Chem Rev 119(6):3510–3673

    Article  CAS  Google Scholar 

  • Pawar SP, Gore AH, Walekar LS, Anbhule PV, Patil SR, Kolekar GB (2015) Turn-on fluorescence probe for selective and sensitive detection of d-penicillamine by CdS quantum dots in aqueous media: application to pharmaceutical formulation. Sens Actuators, B Chem 209:911–918

    Article  CAS  Google Scholar 

  • Ping J, He Z, Liu J, Xie X (2018) Smartphone-based colorimetric chiral recognition of ibuprofen using aptamers-capped gold nanoparticles. Electrophoresis 39(3):486–495

    Article  CAS  Google Scholar 

  • Pinto NJ, Johnson AT, MacDiarmid AG, Mueller CH, Theofylaktos N, Robinson DC, Miranda FA (2003) Electrospun polyaniline/polyethylene oxide nanofiber field-effect transistor. Appl Phys Lett 83(20):4244–4246

    Article  CAS  Google Scholar 

  • Power AC, Morrin A (2013) Electroanalytical sensor technology. InTech, Rijeka, 141–178

  • Pron A, Rannou P (2002) Processible conjugated polymers: from organic semiconductors to organic metals and superconductors. Prog Polym Sci 27(1):135–190

    Article  CAS  Google Scholar 

  • Qian L, Durairaj S, Prins S, Chen A (2021) Nanomaterial-based electrochemical sensors and biosensors for the detection of pharmaceutical compounds. Biosens Bioelectron 175:112836

    Article  CAS  Google Scholar 

  • Qiu H, Wan M, Matthews B, Dai L (2001) Conducting polyaniline nanotubes by template-free polymerization. Macromolecules 34(4):675–677

    Article  CAS  Google Scholar 

  • Quero-Pastor MJ, Garrido-Perez MC, Acevedo A, Quiroga JM (2014) Ozonation of ibuprofen: a degradation and toxicity study. Sci Total Environ 466:957–964

    Article  Google Scholar 

  • Rácz G, Csenki Z, Kovács R, Hegyi Á, Baska F, Sujbert L, Szende B et al (2012) Subacute toxicity assessment of water disinfection byproducts on zebrafish. Pathol Oncol Res 18(3):579–584

    Article  Google Scholar 

  • Radjenović J, Petrović M, Ventura F, Barceló D (2008) Rejection of pharmaceuticals in nanofiltration and reverse osmosis membrane drinking water treatment. Water Res 42(14):3601–3610

    Article  Google Scholar 

  • Ramanathan K, Bangar MA, Yun M, Chen W, Mulchandani A, Myung NV (2004) Individually addressable conducting polymer nanowires array. Nano Lett 4(7):1237–1239

    Article  CAS  Google Scholar 

  • Ramanavicius S, Jagminas A, Ramanavicius A (2021) Advances in molecularly imprinted polymers based affinity sensors. Polymers 13(6):974

    Article  CAS  Google Scholar 

  • Rasmussen SC (2018) Early history of conductive organic polymers. In Conductive Polymers, CRC Press, pp. 1-22

  • Ren C, Song Y, Li Z, Zhu G (2005) Hydrogen peroxide sensor based on horseradish peroxidase immobilized on a silver nanoparticles/cysteamine/gold electrode. Anal Bioanal Chem 381(6):1179–1185

    Article  CAS  Google Scholar 

  • Rivera-Utrilla J, Sánchez-Polo M, Ferro-García MÁ, Prados-Joya G, Ocampo-Pérez R (2013) Pharmaceuticals as emerging contaminants and their removal from water. Rev Chem 93(7):1268–1287

    CAS  Google Scholar 

  • Roh JG, Hwang HR, Yu JB, Lim JO, Huh JS (2002) Oxidant effects on polypyrrole and polyaniline sensor for several volatile organic gases. J Macromol Sci Part A 39(10):1095–1105

    Article  Google Scholar 

  • Rosman N, Salleh WN, Mohamed MA, Jaafar J, Ismail AF, Harun Z (2018) Hybrid membrane filtration-advanced oxidation processes for removal of pharmaceutical residue. J Colloid Interface Sci 532:236–260

    Article  CAS  Google Scholar 

  • Roushani M, Shahdost-Fard F (2015) Fabrication of an ultrasensitive ibuprofen nanoaptasensor based on covalent attachment of aptamer to electrochemically deposited gold-nanoparticles on glassy carbon electrode. Talanta 144:510–516

    Article  CAS  Google Scholar 

  • Roushani M, Shahdost-Fard F (2016) Covalent attachment of aptamer onto nanocomposite as a high performance electrochemical sensing platform: fabrication of an ultra-sensitive ibuprofen electrochemical aptasensor. Mater Sci Eng, C 68:128–135

    Article  CAS  Google Scholar 

  • Roushani M, Shahdost-Fard F (2017) Ultra-sensitive detection of ibuprofen (IBP) by electrochemical aptasensor using the dendrimer-quantum dot (Den-QD) bioconjugate as an immobilization platform with special features. Mater Sci Eng, C 75:1091–1096

    Article  CAS  Google Scholar 

  • Ruggeri G, Ghigo G, Maurino V, Minero C, Vione D (2013) Photochemical transformation of ibuprofen into harmful 4-isobutylacetophenone: pathways, kinetics, and significance for surface waters. Water Res 47(16):6109–6121

    Article  CAS  Google Scholar 

  • Sadik OA, Aluoch AO, Zhou A (2009) Status of biomolecular recognition using electrochemical techniques. Biosens Bioelectron 24(9):2749–2765

    Article  CAS  Google Scholar 

  • Saha K, Agasti SS, Kim C, Li X, Rotello VM (2012) Gold nanoparticles in chemical and biological sensing. Chem Rev 112(5):2739–2779

    Article  CAS  Google Scholar 

  • Saleh TA, Sarı A, Tuzen M (2017) Effective adsorption of antimony (III) from aqueous solutions by polyamide-graphene composite as a novel adsorbent. Chem Eng J 307:230–238

    Article  CAS  Google Scholar 

  • Sanches S, Galinha CF, Crespo MB, Pereira VJ, Crespo JG (2013) Assessment of phenomena underlying the removal of micropollutants during water treatment by nanofiltration using multivariate statistical analysis. Sep Purif Technol 118:377–386

    Article  CAS  Google Scholar 

  • Sanvicens N, Mannelli I, Salvador JP, Valera E, Marco MP (2011) Biosensors for pharmaceuticals based on novel technology. TrAC, Trends Anal Chem 30(3):541–553

    Article  CAS  Google Scholar 

  • Saucier C, Karthickeyan P, Ranjithkumar V, Lima EC, Dos Reis GS, de Brum IA (2017) Efficient removal of amoxicillin and paracetamol from aqueous solutions using magnetic activated carbon. Environ Sci Pollut Res 24(6):5918–5932

    Article  CAS  Google Scholar 

  • Sawall DD, Villahermosa RM, Lipeles RA, Hopkins AR (2004) Interfacial polymerization of polyaniline nanofibers grafted to Au surfaces. Chem Mater 16(9):1606–1608

    Article  CAS  Google Scholar 

  • Sciacca B, Secret E, Pace S, Gonzalez P, Geobaldo F, Quignard F, Cunin F (2011) Chitosan-functionalized porous silicon optical transducer for the detection of carboxylic acid-containing drugs in water. J Mater Chem 21(7):2294–2302

    Article  CAS  Google Scholar 

  • Shariatinia Z (2019) Pharmaceutical applications of chitosan. Adv Coll Interface Sci 263:131–194

    Article  CAS  Google Scholar 

  • Sieber R, Rehberger BS, Walther B (2011) Milk lipids| removal of cholesterol from dairy products

  • Simões FR, Xavier MG (2017) Electrochemical sensors. Nanoscience and its Applications, 155–178

  • Solanki PR, Kaushik A, Ansari AA, Sumana G, Malhotra BD (2011) Horse radish peroxidase immobilized polyaniline for hydrogen peroxide sensor. Polym Adv Technol 22(6):903–908

    Article  CAS  Google Scholar 

  • Song E, Jin-Woo C (2014) A selective hydrogen peroxide sensor based on chemiresistive polyaniline nanowires modified with silver catalytic nanoparticles. J Micromech Microeng 24:606–614

    Article  Google Scholar 

  • Song W, Guo M (2014) Residual veterinary pharmaceuticals in animal manures and their environmental behaviors in soils. In Applied manure and nutrient chemistry for sustainable agriculture and environment. Springer, Dordrecht, 23-52

  • Sousa TFA, Amorim CG, Montenegro MC, Araújo AN (2013) Cyclodextrin based potentiometric sensor for determination of ibuprofen in pharmaceuticals and waters. Sens Actuators, B Chem 176:660–666

    Article  CAS  Google Scholar 

  • Stancova V, Plhalova L, Blahova J, Zivna D, Bartoskova M, Siroka Z, Svobodova Z et al (2017) Effects of the pharmaceutical contaminants ibuprofen, diclofenac, and carbamazepine alone, and in combination, on oxidative stress parameters in early life stages of tench (Tinca tinca). Veterinární Medicína 62(2):90–97

    Article  CAS  Google Scholar 

  • Stenger-Smith JD (1998) Intrinsically electrically conducting polymers. Synthesis, characterization, and their applications. Progress in Polymer Science, 23:1, 57–79

  • Su S, Wu W, Gao J, Lu J, Fan C (2012) Nanomaterials-based sensors for applications in environmental monitoring. J Mater Chem 22(35):18101–18110

    Article  CAS  Google Scholar 

  • Suresh E, Sundaram K, Kavitha B, Kumar NS (2016) Electroanalysis of ibuprofen on conducting polyaniline nanofiber coated glassy carbon surface. Int J Curr Pharmaceut Res 8:44–48

    Article  CAS  Google Scholar 

  • Taghizadeh MT, Nasirianfar S (2018) Ultraviolet irradiation effect on polyvinylpyrrolidone/polyaniline films with additives. Polymer-Plastics Technology and Engineering

  • Tanguy NR, Arjmand M, Yan N (2019) Nanocomposite of nitrogen-doped graphene/polyaniline for enhanced ammonia gas detection. Adv Mater Interfaces 6(16):1900552

    Article  Google Scholar 

  • Tarahomi S, Rounaghi GH, Daneshvar L (2019) A novel disposable sensor based on gold digital versatile disc chip modified with graphene oxide decorated with Ag nanoparticles/β-cyclodextrin for voltammetric measurement of naproxen. Sens Actuators, B Chem 286:445–450

    Article  CAS  Google Scholar 

  • Tawfik SM, Huy BT, Sharipov M, Abd-Elaal A, Lee YI (2018) Enhanced fluorescence of CdTe quantum dots capped with a novel nonionic alginate for selective optosensing of ibuprofen. Sens Actuators, B Chem 256:243–250

    Article  CAS  Google Scholar 

  • Timko MP, Ehlers JD, Roberts PA (2007) Cowpea. In Pulses, sugar and tuber crops. Springer, Berlin, Heidelberg, pp. 49-67

  • Touayi A, Braiek M, Benounis M, Jaffrezic-Renault N (2021) Application of new aptasensor modifies with nanocomposite for selective estradiol valerate determination in pharmaceutical and real biological samples. Monatshefte Fur Chemie-Chemical Monthly 152(6):577–585

    Article  Google Scholar 

  • Tran HD, Shin K, Hong WG, D’Arcy JM, Kojima RW, Weiller BH, Kaner RB (2007) A template-free route to polypyrrole nanofibers. Macromol Rapid Commun 28(24):2289–2293

    Article  CAS  Google Scholar 

  • Verliefde A, Cornelissen E, Amy G, Van der Bruggen B, Van Dijk H (2007) Priority organic micropollutants in water sources in Flanders and the Netherlands and assessment of removal possibilities with nanofiltration. Environ Pollut 146(1):281–289

    Article  CAS  Google Scholar 

  • Virji S, Huang J, Kaner RB, Weiller BH (2004) Polyaniline nanofiber gas sensors: examination of response mechanisms. Nano Lett 4(3):491–496

    Article  CAS  Google Scholar 

  • Wang G, Han R, Su X, Li Y, Xu G, Luo X (2017a) Zwitterionic peptide anchored to conducting polymer PEDOT for the development of antifouling and ultrasensitive electrochemical DNA sensor. Biosens Bioelectron 92:396–401

    Article  CAS  Google Scholar 

  • Wang P, Liu M, Kan J (2009) Amperometric phenol biosensor based on polyaniline. Sens Actuators, B Chem 140(2):577–584

    Article  CAS  Google Scholar 

  • Wang QL, Xie J, Ding LS, Liang J, Luo P, Qing LS (2017b) Development of a nano-SiO2 based enzyme-linked ligand binding assay for the determination of ibuprofen in human urine. Talanta 167:617–622

    Article  CAS  Google Scholar 

  • Wang Y, Liu A, Han Y, Li T (2020) Sensors based on conductive polymers and their composites: a review. Polym Int 69(1):7–17

    Article  CAS  Google Scholar 

  • Wayu MB, Schwarzmann MA, Gillespie SD, Leopold MC (2017) Enzyme-free uric acid electrochemical sensors using β-cyclodextrin-modified carboxylic acid-functionalized carbon nanotubes. J Mater Sci 52(10):6050–6062

    Article  CAS  Google Scholar 

  • Wessling B (1993) Dissipative structure formation in colloidal systems

  • Wijaya L, Alyemeni M, Ahmad P, Alfarhan A, Barcelo D, El-Sheikh MA, Pico Y (2020) Ecotoxicological effects of ibuprofen on plant growth of Vigna unguiculata L. Plants 9(11):1473

    Article  CAS  Google Scholar 

  • Willner MR, Vikesland PJ (2018) Nanomaterial enabled sensors for environmental contaminants. J Nanobiotechnol 16(1):1–16

    Article  Google Scholar 

  • Wong A, Santos AM, Cincotto FH, Moraes FC, Fatibello-Filho O, Sotomayor MD (2020) A new electrochemical platform based on low cost nanomaterials for sensitive detection of the amoxicillin antibiotic in different matrices. Talanta 206:120252

    Article  CAS  Google Scholar 

  • Xie D, Jiang Y, Pan W, Li D, Wu Z, Li Y (2002) Fabrication and characterization of polyaniline-based gas sensor by ultra-thin film technology. Sens Actuators, B Chem 81(2):158–164

    Article  CAS  Google Scholar 

  • Yamamoto T, Koizumi TA (2007) Synthesis of π-conjugated polymers bearing electronic and optical functionalities by organometallic polycondensations and their chemical properties. Polymer 48(19):5449–5472

    Article  CAS  Google Scholar 

  • Yan M, Wu Y (2020) Fabrication and evaluation of bioinspired pDA@ TiO 2-based ibuprofen-imprinted nanocomposite membranes for highly selective adsorption and separation applications. New J Chem 44(25):10703–10712

    Article  CAS  Google Scholar 

  • Yang X, Yang Z (2021) Simple and rapid detection of ibuprofen─ a typical pharmaceuticals and personal care products─ by a liquid crystal aptasensor. Langmuir 38(1):282–288

    Article  Google Scholar 

  • Yao J, Li P, Li L, Yang M (2018) Biochemistry and biomedicine of quantum dots: from biodetection to bioimaging, drug discovery, diagnostics, and therapy. Acta Biomater 74:36–55

    Article  CAS  Google Scholar 

  • Yoon H, Kim JH, Lee N, Kim BG, Jang J (2008) A novel sensor platform based on aptamer-conjugated polypyrrole nanotubes for label-free electrochemical protein detection. ChemBioChem 9(4):634–641

    Article  CAS  Google Scholar 

  • Yoon Y, Westerhoff P, Yoon J, Snyder SA (2004) Removal of 17β estradiol and fluoranthene by nanofiltration and ultrafiltration. J Environ Eng 130(12):1460–2146

    Article  CAS  Google Scholar 

  • Zargar B, Hatamine A (2014) Prussian blue nanoparticles: a simple and fast optical sensor for colorimetric detection of hydrazine in pharmaceutical samples. Anal Methods 6(15):5951–5956

    Article  CAS  Google Scholar 

  • Zhang C, She Y, Li T, Zhao F, Jin M, Guo Y, Wang J (2017a) A highly selective electrochemical sensor based on molecularly imprinted polypyrrole-modified gold electrode for the determination of glyphosate in cucumber and tap water. Anal Bioanal Chem 409(30):7133–7144

    Article  CAS  Google Scholar 

  • Zhang DQ, Hua T, Gersberg RM, Zhu J, Tan SK (2013) Carbamazepine and naproxen: fate in wetland mesocosms planted with Scirpus validus. Chemosphere 91(1):14–21

    Article  CAS  Google Scholar 

  • Zhang L, Wan M (2003) Self-assembly of polyaniline—from nanotubes to hollow microspheres. Adv Func Mater 13(10):815–820

    Article  CAS  Google Scholar 

  • Zhang X, Lee JS, Lee GS, Cha DK, Kim MJ, Yang DJ, Manohar SK (2006) Chemical synthesis of PEDOT nanotubes. Macromolecules 39(2):470–472

    Article  Google Scholar 

  • Zhang Z, Xu J, Wen Y, Zhang J, Ding W (2017b) The electro-synthesized imprinted PEDOT film as a simple voltammetric sensor for highly sensitive and selective detection of vitamin K3 in poultry drug samples. Synth Met 230:79–88

    Article  CAS  Google Scholar 

  • Zhao J, Guo W, Pei M, Ding F (2016) GR–Fe 3 O 4 NPs and PEDOT–AuNPs composite based electrochemical aptasensor for the sensitive detection of penicillin. Anal Methods 8(22):4391–4397

    Article  CAS  Google Scholar 

  • Zheng BG, Zheng Z, Zhang JB, Luo XZ, Wang JQ, Liu Q, Wang LH (2011) Degradation of the emerging contaminant ibuprofen in aqueous solution by gamma irradiation. Desalination 276:379–385

    Article  CAS  Google Scholar 

  • Zhou C, Han J, Guo R (2009) Synthesis of polyaniline hierarchical structures in a dilute SDS/HCl solution: nanostructure-covered rectangular tubes. Macromolecules 42(4):1252–1257

    Article  CAS  Google Scholar 

  • Zhou H, Smith DW (2001) Advanced technologies in water and wastewater treatment. Can J Civ Eng 28(S1):49–66

    Article  Google Scholar 

  • Zhu Y, Hu D, Wan MX, Jiang L, Wei Y (2007) Conducting and superhydrophobic rambutan-like hollow spheres of polyaniline. Adv Mater 19(16):2092–2096

    Article  CAS  Google Scholar 

  • Zhu X, Shi L (2019) Nano-inspired biosensors for protein assay with clinical applications. Elsevier, 209–236

  • Zur J, Piński A, Marchlewicz A, Hupert-Kocurek K, Wojcieszyńska D, Guzik U (2018) Organic micropollutants paracetamol and ibuprofen—toxicity, biodegradation, and genetic background of their utilization by bacteria. Environ Sci Pollut Res 25(22):21498–21524

    Article  CAS  Google Scholar 

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Acknowledgements

We would like to acknowledge the Water Research Commission for the research opportunity.

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  1. Institute for Nanotechnology and Water Sustainability (iNanoWS), College of Science, Engineering and Technology, University of South Africa, Florida Campus, Johannesburg, 1710, South Africa

    Ntombenhle Masanabo, Benjamin Orimolade, Azeez O. Idris, Thabo T. I. Nkambule, Bhekie B. Mamba & Usisipho Feleni

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  1. Ntombenhle Masanabo
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Contributions

All authors contributed to the study conception and design. Ntombenhle Masanabo and Usisipho Feleni conceptualized the idea, coordinated the writing of the review article, and compiled the various sections contributed by other authors (Benjamin Orimolade, Azeez O. Idris, Thabo T.I Nkambule, and Bhekie B. Mamba). The first draft of the manuscript was written by Ntombenhle Masanabo, and all authors commented on previous versions of the manuscript. Benjamin Orimolade and Azeez O. Idris contributed to correcting the sections on electrochemical sensor applications. All authors read and approved the final manuscript.

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Correspondence to Usisipho Feleni.

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Masanabo, N., Orimolade, B., Idris, A.O. et al. Advances in polymer-based detection of environmental ibuprofen in wastewater. Environ Sci Pollut Res 30, 14062–14090 (2023). https://doi.org/10.1007/s11356-022-24858-w

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