Abstract
Aedes (Stegomyia) aegypti is a cosmopolitan species that transmits arbovirus of medical importance as dengue, Zika, and chikungunya. The main strategy employed for the control of this mosquito is the use of larvicidal agents. However, the overuse of synthetic chemical larvicides has led to an increase in resistant insects, making management difficult. Therefore, the use of botanical insecticide–based nanosystems as an alternative to the use of synthetic agents for the control of Ae. aegypti has gained more considerable attention in the last years, mainly due to the advantages of nanostructured delivery systems, such as (a) controlled release; (b) greater surface area; (c) improvement of biological activity; (d) protection of natural bioactive agents from the environment and thus achieving stability; and (e) lipophilic drugs are easier dispersed even in aqueous vehicles. This review summarizes the current knowledge about botanical insecticide–based nanosystems as larvicidal against Ae. aegypti larvae. The majority of papers used metallic nanoparticles (NPs) as larvicidal agents, mainly silver nanoparticles (AgNPs), showing potential for their use as an alternative, followed by nanoemulsions containing vegetable oils, most essential oils, nanosystems that allow the dispersion of this high hydrophobic product in water, the environment of larval development. The final section describes scientific findings about the mode of action of these NPs, showing the gap about this subject in literature.
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References
Aarthi C, Govindarajan M, Rajaraman P, Alharbi NS, Kadaikunnan S, Khaled JM, Mothana RA, Siddiqui NA, Benelli G (2018) Eco-friendly and cost-effective Ag nanocrystals fabricated using the leaf extract of Habenaria plantaginea: toxicity on six mosquito vectors and four non-target species. Environ Sci Pollut Res 25:10317–10327. https://doi.org/10.1007/s11356-017-9203-2
Ahmed T, Hyder MZ, Liaqat I, Scholz M (2019) Climatic conditions: conventional and nanotechnology-based methods for the control of mosquito vectors causing human health issues. Int J Environ Res Public Health 16:3165. https://doi.org/10.3390/ijerph16173165
Alharbi NS, Govindarajan M, Kadaikunnan S, Khaled JM, Almanaa TN, Alyahya SA, al-anbr MN, Gopinath K, Sudha A (2018) Nanosilver crystals capped with Bauhinia acuminata phytochemicals as new antimicrobials and mosquito larvicides. J Trace Elem Med Biol 50:146–153. https://doi.org/10.1016/j.jtemb.2018.06.016
Alphey L, McKemey A, Nimmo D, Neira Oviedo M, Lacroix R, Matzen K, Beech C (2013) Genetic control of Aedes mosquitoes. Pathog Glob Health 107:170–179. https://doi.org/10.1179/2047773213Y.0000000095
AlQahtani FS, AlShebly MM, Govindarajan M et al (2017) Green and facile biosynthesis of silver nanocomposites using the aqueous extract of Rubus ellipticus leaves: toxicity and oviposition deterrent activity against Zika virus, malaria and filariasis mosquito vectors. J Asia Pac Entomol 20:157–164. https://doi.org/10.1016/j.aspen.2016.12.004
Amado JRR, Prada AL, Diaz JG, Souto RNP, Arranz JCE, de Souza TP (2020) Development, larvicide activity, and toxicity in nontarget species of the Croton linearis Jacq essential oil nanoemulsion. Environ Sci Pollut Res 27:9410–9423. https://doi.org/10.1007/s11356-020-07608-8
Angajala G, Ramya R, Subashini R (2014) In-vitro anti-inflammatory and mosquito larvicidal efficacy of nickel nanoparticles phytofabricated from aqueous leaf extracts of Aegle marmelos Correa. Acta Trop 135:19–26 https://doi.org/10.1016/j.actatropica.2014.03.012
Anjali C, Sharma Y, Mukherjee A, Chandrasekaran N (2012) Neem oil (Azadirachta indica) nanoemulsion-a potent larvicidal agent against Culex quinquefasciatus. Pest Manag Sci 68:158–163. https://doi.org/10.1002/ps.2233
Ashokan AP, Paulpandi M, Dinesh D, Murugan K, Vadivalagan C, Benelli G (2017) Toxicity on dengue mosquito vectors through Myristica fragrans-synthesized zinc oxide nanorods, and their cytotoxic effects on liver cancer cells (HepG2). J Clust Sci 28:205–226. https://doi.org/10.1007/s10876-016-1075-y
Aswini R, Murugesan S, Kannan K (2020) Bio-engineered TiO2 nanoparticles using Ledebouria revoluta extract: larvicidal, histopathological, antibacterial and anticancer activity. Int J Environ Anal Chem 00:1–11. https://doi.org/10.1080/03067319.2020.1718668
Aziz AT, Alshehri MA, Panneerselvam C, Murugan K, Trivedi S, Mahyoub JA, Hassan M'M, Maggi F, Sut S, Dall'Acqua S, Canale A, Benelli G (2018) The desert wormwood (Artemisia herba-alba) – from Arabian folk medicine to a source of green and effective nanoinsecticides against mosquito vectors. J Photochem Photobiol B Biol 180:225–234
Balasubramani G, Ramkumar R, Krishnaveni N, Sowmiya R, Deepak P, Arul D, Perumal P (2015) GC-MS analysis of bioactive components and synthesis of gold nanoparticle using Chloroxylon swietenia DC leaf extract and its larvicidal activity. J Photochem Photobiol B Biol 148:1–8. https://doi.org/10.1016/j.jphotobiol.2015.03.016
Balasubramani S, Rajendhiran T, Moola AK, Diana RKB (2017) Development of nanoemulsion from Vitex negundo L. essential oil and their efficacy of antioxidant, antimicrobial and larvicidal activities (Aedes aegypti L.). Environ Sci Pollut Res 24:15125–15133. https://doi.org/10.1007/s11356-017-9118-y
Barik TK, Kamaraju R, Gowswami A (2012) Silica nanoparticle: a potential new insecticide for mosquito vector control. Parasitol Res 111:1075–1083. https://doi.org/10.1007/s00436-012-2934-6
Baylis M (2017) Potential impact of climate change on emerging vector-borne and other infections in the UK. Environ Health A Glob Access Sci Sour 16:112. https://doi.org/10.1186/s12940-017-0326-1
Benelli G (2018) Mode of action of nanoparticles against insects. Environ Sci Pollut Res 25:12329–12341. https://doi.org/10.1007/s11356-018-1850-4
Benelli G, Govindarajan M, Senthilmurugan S, Vijayan P, Kadaikunnan S, Alharbi NS, Khaled JM (2018) Fabrication of highly effective mosquito nanolarvicides using an Asian plant of ethno-pharmacological interest, Priyangu (Aglaia elaeagnoidea): toxicity on non-target mosquito natural enemies. Environ Sci Pollut Res 25:10283–10293. https://doi.org/10.1007/s11356-017-8898-4
Bhakyaraj K, Kumaraguru S, Gopinath K, Sabitha V, Kaleeswarran PR, Karthika V, Sudha A, Muthukumaran U, Jayakumar K, Mohan S, Arumugam A (2017) Eco-friendly synthesis of palladium nanoparticles using Melia azedarach leaf extract and their evaluation for antimicrobial and larvicidal activities. J Clust Sci 28:463–576
Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, Drake JM, Brownstein JS, Hoen AG, Sankoh O, Myers MF, George DB, Jaenisch T, Wint GRW, Simmons CP, Scott TW, Farrar JJ, Hay SI (2013) The global distribution and burden of dengue. Nature 496:504–507. https://doi.org/10.1038/nature12060
Bisset J, Rodríguez MM, Fernández D (2006) Selection of insensitive acetylcholinesterase as a resistance mechanism in Aedes aegypti (Diptera: Culicidae) from Santiago de Cuba. J Med Entomol 43:1185–1189. https://doi.org/10.1603/0022-2585(2006)43[1185:soiaaa]2.0.co;2
Botas G, Cruz R, de Almeida F, Duarte J, Araújo R, Souto R, Ferreira R, Carvalho J, Santos M, Rocha L, Pereira V, Fernandes C (2017) Baccharis reticularia DC. and limonene nanoemulsions: promising larvicidal agents for Aedes aegypti (Diptera: Culicidae) Control. Molecules 22:1990. https://doi.org/10.3390/molecules22111990
Caragata EP, Dutra HLC, Moreira LA (2016) Exploiting intimate relationships: controlling mosquito-transmitted disease with Wolbachia. Trends Parasitol 32:207–218. https://doi.org/10.1016/j.pt.2015.10.011
Cavalcanti ESB, de Morais SM, Lima MAA, Santana EWP (2004) Larvicidal activity of essential oils from Brazilian plants against Aedes aegypti L. Mem Inst Oswaldo Cruz 99:541–544 https://doi.org/10.1590/S0074-02762004000500015
Chitra G, Balasubramani G, Ramkumar R, Sowmiya R, Perumal P (2015) Mukia maderaspatana (Cucurbitaceae) extract-mediated synthesis of silver nanoparticles to control Culex quinquefasciatus and Aedes aegypti (Diptera: Culicidae). Parasitol Res 114:1407–1415. https://doi.org/10.1007/s00436-015-4320-7
Ciccia G, Coussio J, Mongelli E (2000) Insecticidal activity against Aedes aegypti larvae of some medicinal South American plants. J Ethnopharmacol 72:185–189. https://doi.org/10.1016/S0378-8741(00)00241-5
Consoli RAGB, Oliveiera RL (1998) Principais mosquitos de importância sanitária no Brasil, 1st edn. Fundação Oswaldo Cruz, Rio de Janeiro
da Silva MRM, Ricci-Júnior E (2020) An approach to natural insect repellent formulations: from basic research to technological development. Acta Trop 105419:105419. https://doi.org/10.1016/j.actatropica.2020.105419
Duarte JL, Amado JRR, Oliveira AEMFM, Cruz RAS, Ferreira AM, Souto RNP, Falcão DQ, Carvalho JCT, Fernandes CP (2015) Evaluation of larvicidal activity of a nanoemulsion of Rosmarinus officinalis essential oil. Rev Bras Farmacogn 25:189–192
Dusfour I, Vontas J, David JP, Weetman D, Fonseca DM, Corbel V, Raghavendra K, Coulibaly MB, Martins AJ, Kasai S, Chandre F (2019) Management of insecticide resistance in the major Aedes vectors of arboviruses: advances and challenges. PLoS Negl Trop Dis 13:1–22. https://doi.org/10.1371/journal.pntd.0007615
Elumalai D, Hemavathi M, Deepaa CV, Kaleena PK (2017) Evaluation of phytosynthesised silver nanoparticles from leaf extracts of Leucas aspera and Hyptis suaveolens and their larvicidal activity against malaria, dengue and filariasis vectors. Parasit Epidemiol Control 2:15–26. https://doi.org/10.1016/j.parepi.2017.09.001
Fernández-Salas I, Danis-Lozano R, Casas-Martínez M, Ulloa A, Bond JG, Marina CF, Lopez-Ordóñez T, Elizondo-Quiroga A, Torres-Monzón JA, Díaz-González EE (2015) Historical inability to control Aedes aegypti as a main contributor of fast dispersal of chikungunya outbreaks in Latin America. Antivir Res 124:30–42. https://doi.org/10.1016/j.antiviral.2015.10.015
Ferreira RMA, Duarte JL, Cruz RAS, Oliveira AEMFM, Araújo RS, Carvalho JCT, Mourão RHV, Souto RNP, Fernandes CP (2019) A herbal oil in water nano-emulsion prepared through an ecofriendly approach affects two tropical disease vectors. Rev Bras Farmacogn 29:778–784. https://doi.org/10.1016/j.bjp.2019.05.003
Fouet C, Kamdem C (2019) Integrated mosquito management: is precision control a luxury or necessity? Trends Parasitol 35:85–95. https://doi.org/10.1016/j.pt.2018.10.004
Gharsan FN (2019) A review of the bioactivity of plant products against Aedes aegypti (Diptera: Culicidae). J Entomol Sci 54:256. https://doi.org/10.18474/JES18-82
Ghosh SK, Chakaravarthy P, Panch SR, Krishnappa P, Tiwari S, Ojha VP, R M, Dash AP (2011) Comparative efficacy of two poeciliid fish in indoor cement tanks against chikungunya vector Aedes aegypti in villages in Karnataka, India. BMC Public Health 11:1–8. https://doi.org/10.1186/1471-2458-11-599
Ghosh V, Mukherjee A, Chandrasekaran N (2013) Formulation and characterization of plant essential oil based nanoemulsion: evaluation of its larvicidal activity against Aedes aegypti. Asian J Chem 25
Ghosh V, Mukherjee A, Chandrasekaran N (2014) Optimization of process parameters to formulate nanoemulsion by spontaneous emulsification: evaluation of larvicidal activity against Culex quinquefasciatus larva. Bionanoscience 4:157–165 https://doi.org/10.1007/s12668-014-0131-z
Gnanadesigan M, Anand M, Ravikumar S, Maruthupandy M, Vijayakumar V, Selvam S, Dhineshkumar M, Kumaraguru AK (2011) Biosynthesis of silver nanoparticles by using mangrove plant extract and their potential mosquito larvicidal property. Asian Pac J Trop Med 4:799–803. https://doi.org/10.1016/S1995-7645(11)60197-1
Gomathi M, Prakasam A, Chandrasekaran R, Gurusubramaniam G, Revathi K, Rajeshkumar S (2019) Assessment of silver nanoparticle from Cocos nucifera (coconut) shell on dengue vector toxicity, detoxifying enzymatic activity and predatory response of aquatic organism. J Clust Sci 7:1525–1532. https://doi.org/10.1007/s10876-019-01596-7
Govindarajan M, Hoti SL, Rajeswary M, Benelli G (2016) One-step synthesis of polydispersed silver nanocrystals using Malva sylvestris: an eco-friendly mosquito larvicide with negligible impact on non-target aquatic organisms. Parasitol Res 115:2685–2695. https://doi.org/10.1007/s00436-016-5038-x
Gray L, Florez SD, Barreiro AM, Vadillo-Sánchez J, González-Olvera G, Lenhart A, Manrique-Saide P, Vazquez-Prokopec GM (2018) Experimental evaluation of the impact of household aerosolized insecticides on pyrethroid resistant Aedes aegypti. Sci Rep 8:1–11. https://doi.org/10.1038/s41598-018-30968-8
Gubler DJ, Halstead SB (2019) Is Dengvaxia a useful vaccine for dengue endemic areas? Bmj 5710:l5710 https://doi.org/10.1136/bmj.l5710
Gutiérrez JM, González C, Maestro A, Solè I, Pey CM, Nolla J (2008) Nano-emulsions: new applications and optimization of their preparation. Curr Opin Colloid Interface Sci 13:245–251. https://doi.org/10.1016/j.cocis.2008.01.005
Haghighat-Khah RE, Harvey-Samuel T, Basu S, StJohn O, Scaife S, Verkuijl S, Lovett E, Alphey L (2019) Engineered action at a distance: blood-mealinducible paralysis in Aedes aegypti. PLoS Negl Trop Dis 13:1–17. https://doi.org/10.1371/journal.pntd.0007579
Hoffmann AA, Montgomery BL, Popovici J, Iturbe-Ormaetxe I, Johnson PH, Muzzi F, Greenfield M, Durkan M, Leong YS, Dong Y, Cook H, Axford J, Callahan AG, Kenny N, Omodei C, McGraw EA, Ryan PA, Ritchie SA, Turelli M, O’Neill SL (2011) Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission. Nature 476:454–459. https://doi.org/10.1038/nature10356
Ishwarya R, Vaseeharan B, Anuradha R, Rekha R, Govindarajan M, Alharbi NS, Kadaikunnan S, Khaled JM, Benelli G (2017) Eco-friendly fabrication of Ag nanostructures using the seed extract of Pedalium murex, an ancient Indian medicinal plant: histopathological effects on the Zika virus vector Aedes aegypti and inhibition of biofilm-forming pathogenic bacteria. J Photochem Photobiol B Biol 174:133–143. https://doi.org/10.1016/j.jphotobiol.2017.07.026
Islan GA, Durán M, Cacicedo ML, Nakazato G, Kobayashi RKT, Martinez DST, Castro GR, Durán N (2017) Nanopharmaceuticals as a solution to neglected diseases: is it possible? Acta Trop 170:16–42. https://doi.org/10.1016/j.actatropica.2017.02.019
Jampílek J, Kráľová K (2019) Nanobiopesticides in agriculture: state of the art and future opportunities. In: Nano-Biopesticides Today and Future Perspectives. Elsevier, pp 397–447
Jesus FLM, De Almeida FB, Duarte JL et al (2017, 2017) Preparation of a nanoemulsion with Carapa guianensis Aublet (Meliaceae) oil by a low-energy/solvent-free method and evaluation of its preliminary residual larvicidal activity. Evid Based Complement Alternat Med. https://doi.org/10.1155/2017/6756793
Jinu U, Rajakumaran S, Senthil-Nathan S, Geetha N, Venkatachalam P (2018) Potential larvicidal activity of silver nanohybrids synthesized using leaf extracts of Cleistanthus collinus (Roxb.) Benth. ex Hook.f. and Strychnos nux-vomica L. nux-vomica against dengue, Chikungunya and Zika vectors. Physiol Mol Plant Pathol 101:163–171. https://doi.org/10.1016/j.pmpp.2017.05.003
Johnson PH, Williams CR, Silcock RM et al (2009) A lethal ovitrap-based mass trapping scheme for dengue control in Australia: II. Impact on populations of the mosquito Aedes aegypti. Med Vet Entomol 23:303–316. https://doi.org/10.1111/j.1365-2915.2009.00834.x
Johnson BJ, Ritchie SA, Fonseca DM (2017) The state of the art of lethal oviposition trap-based mass interventions for arboviral control. Insects:8. https://doi.org/10.3390/insects8010005
Kalaiselvi A, Aswin Jeno JG, Roopan SM, Madhumitha G, Nakkeeran E (2019) Chemical composition of clove bud oil and development of clove bud oil loaded niosomes against three larvae species. Int Biodeterior Biodegrad 137:102–108. https://doi.org/10.1016/j.ibiod.2018.12.004
Kovendan K, Chandramohan B, Dinesh D, Abirami D, Vijayan P, Govindarajan M, Vincent S, Benelli G (2016) Green-synthesized silver nanoparticles using Psychotria nilgiriensis: toxicity against the dengue vector Aedes aegypti (Diptera: Culicidae) and impact on the predatory efficiency of the non-target organism Poecilia sphenops (Cyprinodontiformes: Poeciliida). J Asia Pac Entomol 19:1001–1007. https://doi.org/10.1016/j.aspen.2016.09.001
Kudom AA (2020) Entomological surveillance to assess potential outbreak of Aedes-borne arboviruses and insecticide resistance status of Aedes aegypti from Cape Coast, Ghana. Acta Trop 202:105257. https://doi.org/10.1016/j.actatropica.2019.105257
Kumar D, Kumar G, Agrawal V (2018) Green synthesis of silver nanoparticles using Holarrhena antidysenterica (L.) Wall.bark extract and their larvicidal activity against dengue and filariasis vectors. Parasitol Res 117:377–389 https://doi.org/10.1007/s00436-017-5711-8
Li W, Huang C, Wang K, Fu J, Cheng D, Zhang Z (2015) Laboratory evaluation of aqueous leaf extract of Tephrosia vogelii against larvae of Aedes albopictus (Diptera: Culicidae) and non-target aquatic organisms. Acta Trop 146:36–41. https://doi.org/10.1016/j.actatropica.2015.02.004
Maia JD, La Corte R, Martinez J et al (2019) Improved activity of thyme essential oil (Thymus vulgaris) against Aedes aegypti larvae using a biodegradable controlled release system. Ind Crop Prod 136:110–120. https://doi.org/10.1016/j.indcrop.2019.03.040
Mann SR, Kaufman EP (2012) Natural product pesticides: their development, delivery and use against insect vectors. Mini Rev Org Chem 9:185–202. https://doi.org/10.2174/157019312800604733
Martins MM, Prata-Barbosa A, da Cunha AJLA (2019) Arboviral diseases in pediatrics†. J Pediatr 96:2–11. https://doi.org/10.1016/j.jped.2019.08.005
Mishra P, Samuel MK, Reddy R, Tyagi BK, Mukherjee A, Chandrasekaran N (2018) Environmentally benign nanometric neem-laced urea emulsion for controlling mosquito population in environment. Environ Sci Pollut Res 25:2211–2230. https://doi.org/10.1007/s11356-017-0591-0
Moreira LA, Iturbe-Ormaetxe I, Jeffery JA, Lu G, Pyke AT, Hedges LM, Rocha BC, Hall-Mendelin S, Day A, Riegler M, Hugo LE, Johnson KN, Kay BH, McGraw EA, van den Hurk AF, Ryan PA, O'Neill SL (2009) A Wolbachia symbiont in Aedes aegypti limits infection with dengue, chikungunya, and plasmodium. Cell 139:1268–1278. https://doi.org/10.1016/j.cell.2009.11.042
Muthukumaran U, Govindarajan M, Rajeswary M (2015a) Green synthesis of silver nanoparticles from Cassia roxburghii—a most potent power for mosquito control. Parasitol Res 114:4385–4395. https://doi.org/10.1007/s00436-015-4677-7
Muthukumaran U, Govindarajan M, Rajeswary M, Hoti SL (2015b) Synthesis and characterization of silver nanoparticles using Gmelina asiatica leaf extract against filariasis, dengue, and malaria vector mosquitoes. Parasitol Res 114:1817–1827. https://doi.org/10.1007/s00436-015-4368-4
Nazeer AA, Rajan HV, Vijaykumar SD, Saravanan M (2019) Evaluation of larvicidal and repellent activity of nanocrystal emulsion synthesized from F. glomerata and neem oil against mosquitoes. J Clust Sci 0123456789:1649–1661. https://doi.org/10.1007/s10876-019-01611-x
Nuchuchua O, Sakulku U, Uawongyart N, Puttipipatkhachorn S, Soottitantawat A, Ruktanonchai U (2009) In vitro characterization and mosquito (Aedes aegypti) repellent activity of essential-oils-loaded nanoemulsions. AAPS PharmSciTech 10:1234–1242. https://doi.org/10.1208/s12249-009-9323-1
Oliveira AEMFM, Duarte JL, Amado JRR, Cruz RAS, Rocha CF, Souto RNP, Ferreira RMA, Santos K, da Conceição EC, de Oliveira LAR, Kelecom A, Fernandes CP, Carvalho JCT (2016) Development of larvicidal nanoemulsion with pterodon emarginatus Vogel oil. PLoS One 11:e0145835. https://doi.org/10.1371/journal.pone.0145835
Oliveira AEMFM, Bezerra DC, Duarte JL, Cruz RAS, Souto RNP, Ferreira RMA, Nogueira J, da Conceição EC, Leitão S, Bizzo HR, Gama PE, Carvalho JCT, Fernandes CP (2017) Essential oil from Pterodon emarginatus as a promising natural raw material for larvicidal nanoemulsions against a tropical disease vector. Sustain Chem Pharm 6:1–9. https://doi.org/10.1016/j.scp.2017.06.001
Parthiban E, Manivannan N, Ramanibai R, Mathivanan N (2019) Green synthesis of silver-nanoparticles from Annona reticulata leaves aqueous extract and its mosquito larvicidal and anti-microbial activity on human pathogens. Biotechnol Reports 21:e00297 https://doi.org/10.1016/j.btre.2018.e00297
Patil CD, Borase HP, Patil SV, Salunkhe RB, Salunke BK (2012a) Larvicidal activity of silver nanoparticles synthesized using Pergularia daemia plant latex against Aedes aegypti and Anopheles stephensi and nontarget fish Poecillia reticulata. Parasitol Res 111:555–562. https://doi.org/10.1007/s00436-012-2867-0
Patil CD, Patil SV, Borase HP, Salunke BK, Salunkhe RB (2012b) Larvicidal activity of silver nanoparticles synthesized using Plumeria rubra plant latex against Aedes aegypti and Anopheles stephensi. Parasitol Res 110:1815–1822. https://doi.org/10.1007/s00436-011-2704-x
Pavela R, Benelli G, Pavoni L, Bonacucina G, Cespi M, Cianfaglione K, Bajalan I, Morshedloo MR, Lupidi G, Romano D, Canale A, Maggi F (2019a) Microemulsions for delivery of Apiaceae essential oils—towards highly effective and eco-friendly mosquito larvicides? Ind Crop Prod 129:631–640. https://doi.org/10.1016/j.indcrop.2018.11.073
Pavela R, Pavoni L, Bonacucina G, Cespi M, Kavallieratos NG, Cappellacci L, Petrelli R, Maggi F, Benelli G (2019b) Rationale for developing novel mosquito larvicides based on isofuranodiene microemulsions. J Pest Sci 92(2004):909–921. https://doi.org/10.1007/s10340-018-01076-3
Peniche T, Duarte LL, Amaral FAS et al (2019) Hyptis suaveolens (L.) Poit. Essential oil: a raw material for a larvicidal nano-emulsion. Lat Am J Pharm 38:938–944
Poopathi S, De Britto LJ, Praba VL et al (2015) Synthesis of silver nanoparticles from Azadirachta indica—a most effective method for mosquito control. Environ Sci Pollut Res 22:2956–2963. https://doi.org/10.1007/s11356-014-3560-x
Portilla Cabrera CV, Selvaraj JJ (2020) Geographic shifts in the bioclimatic suitability for Aedes aegypti under climate change scenarios in Colombia. Heliyon 6:e03101 https://doi.org/10.1016/j.heliyon.2019.e03101
Pravena A, Sanjayan KP (2011) Inhibition of acetylcholisterase in three insects of economic importance by linalool, a monoterpene phytochemical. Insect Pest Manag:340–345
Rajaganesh R, Murugan K, Panneerselvam C, Jayashanthini S, Aziz AT, Roni M, Suresh U, Trivedi S, Rehman H, Higuchi A, Nicoletti M, Benelli G (2016) Fern-synthesized silver nanocrystals: towards a new class of mosquito oviposition deterrents? Res Vet Sci 109:40–51. https://doi.org/10.1016/j.rvsc.2016.09.012
Rajkumar R, Shivakumar MS, Senthil Nathan S, Selvam K (2018) Pharmacological and larvicidal potential of green synthesized silver nanoparticles using Carmona retusa (Vahl) Masam leaf extract. J Clust Sci 29:1243–1253. https://doi.org/10.1007/s10876-018-1443-x
Rattan RS (2010) Mechanism of action of insecticidal secondary metabolites of plant origin. Crop Prot 29:913–920. https://doi.org/10.1016/j.cropro.2010.05.008
Reis NN, da Silva AL, Reis EPG et al (2017) Viruses vector control proposal: genus Aedes emphasis. Braz J Infect Dis 21:457–463. https://doi.org/10.1016/j.bjid.2017.03.020
Rodrigues E d CR, Ferreir AM, Vilhen JCE et al (2014) Development of a larvicidal nanoemulsion with Copaiba (Copaifera duckei) oleoresin. Braz J Pharmacogn 24:699–705. https://doi.org/10.1016/j.bjp.2014.10.013
Roiz D, Wilson AL, Scott TW, Fonseca DM, Jourdain F, Müller P, Velayudhan R, Corbel V (2018) Integrated Aedes management for the control of Aedes-borne diseases. PLoS Negl Trop Dis 12:1–21. https://doi.org/10.1371/journal.pntd.0006845
Romero G, Moya SE (2012) Synthesis of organic nanoparticles. In: Frontiers of Nanoscience, 1st edn. Elsevier LTD, pp 115–141
Sakulku U, Nuchuchua O, Uawongyart N, Puttipipatkhachorn S, Soottitantawat A, Ruktanonchai U (2009) Characterization and mosquito repellent activity of citronella oil nanoemulsion. Int J Pharm 372:105–111. https://doi.org/10.1016/j.ijpharm.2008.12.029
Schröfel A, Kratošová G, Šafařík I, Šafaříková M, Raška I, Shor LM (2014) Applications of biosynthesized metallic nanoparticles - A review. Acta Biomater 10:4023–4042. https://doi.org/10.1016/j.actbio.2014.05.022
Shahzad K, Manzoor F (2019) Nanoformulations and their mode of action in insects: a review of biological interactions. Drug Chem Toxicol:1–11. https://doi.org/10.1080/01480545.2018.1525393
Sharma A, Kumar S, Tripathi P (2019) A facile and rapid method for green synthesis of Achyranthes aspera stem extract-mediated silver nano-composites with cidal potential against Aedes aegypti L. Saudi J Biol Sci 26:698–708. https://doi.org/10.1016/j.sjbs.2017.11.001
Sharma A, Tripathi P, Kumar S (2020) One-pot synthesis of silver nanocomposites from Achyranthes aspera: an eco-friendly larvicide against Aedes aegypti L. Asian Pac J Trop Biomed 10:54–64 https://doi.org/10.4103/2221-1691.275420
Silva IMA, Martins GF, Melo CR, Santana AS, Faro RRN, Blank AF, Alves PB, Picanço MC, Cristaldo PF, Araújo APA, Bacci L (2018) Alternative control of Aedes aegypti resistant to pyrethroids: lethal and sublethal effects of monoterpene bioinsecticides. Pest Manag Sci 74:1001–1012. https://doi.org/10.1002/ps.4801
Silva LS, Mar JM, Azevedo SG, Rabelo MS, Bezerra JA, Campelo PH, Machado MB, Trovati G, dos Santos AL, da Fonseca Filho HD, de Souza TP, Sanches EA (2019) Encapsulation of Piper aduncum and Piper hispidinervum essential oils in gelatin nanoparticles: a possible sustainable control tool of Aedes aegypti, Tetranychus urticae and Cerataphis lataniae. J Sci Food Agric 99:685–695. https://doi.org/10.1002/jsfa.9233
Solans C, Izquierdo P, Nolla J et al (2005) Nano-emulsions. Curr Opin Colloid Interface Sci 10:102–110. https://doi.org/10.1016/j.cocis.2005.06.004
Souza-Neto JA, Powell JR, Bonizzoni M (2019) Aedes aegypti vector competence studies: a review. Infect Genet Evol 67:191–209. https://doi.org/10.1016/j.meegid.2018.11.009
Suganya P, Vaseeharan B, Vijayakumar S, Balan B, Govindarajan M, Alharbi NS, Kadaikunnan S, Khaled JM, Benelli G (2017) Biopolymer zein-coated gold nanoparticles: synthesis, antibacterial potential, toxicity and histopathological effects against the Zika virus vector Aedes aegypti. J Photochem Photobiol B Biol 173:404–411. https://doi.org/10.1016/j.jphotobiol.2017.06.004
Sugumar S, Clarke SK, Nirmala MJ, Tyagi BK, Mukherjee A, Chandrasekaran N (2014) Nanoemulsion of eucalyptus oil and its larvicidal activity against Culex quinquefasciatus. Bull Entomol Res 104:393–402. https://doi.org/10.1017/S0007485313000710
Sundararajan B, Ranjitha Kumari BD (2017) Novel synthesis of gold nanoparticles using Artemisia vulgaris L. leaf extract and their efficacy of larvicidal activity against dengue fever vector Aedes aegypti L. J Trace Elem Med Biol 43:187–196. https://doi.org/10.1016/j.jtemb.2017.03.008
Suresh G, Gunasekar PH, Kokila D, Prabhu D, Dinesh D, Ravichandran N, Ramesh B, Koodalingam A, Vijaiyan Siva G (2014) Green synthesis of silver nanoparticles using Delphinium denudatum root extract exhibits antibacterial and mosquito larvicidal activities. Spectrochim Acta A Mol Biomol Spectrosc 127:61–66. https://doi.org/10.1016/j.saa.2014.02.030
Suresh U, Murugan K, Panneerselvam C, Rajaganesh R, Roni M, Aziz AT, Naji al-Aoh HA, Trivedi S, Rehman H, Kumar S, Higuchi A, Canale A, Benelli G (2018) Suaeda maritima-based herbal coils and green nanoparticles as potential biopesticides against the dengue vector Aedes aegypti and the tobacco cutworm Spodoptera litura. Physiol Mol Plant Pathol 101:225–235. https://doi.org/10.1016/j.pmpp.2017.01.002
Thakkar KN, Mhatre SS, Parikh RY (2010) Biological synthesis of metallic nanoparticles. Nanomed Nanotechnol Biol Med 6:257–262. https://doi.org/10.1016/j.nano.2009.07.002
Thandapani K, Kathiravan M, Namasivayam E, Padiksan IA, Natesan G, Tiwari M, Giovanni B, Perumal V (2018) Enhanced larvicidal, antibacterial, and photocatalytic efficacy of TiO 2 nanohybrids green synthesized using the aqueous leaf extract of Parthenium hysterophorus. Environ Sci Pollut Res 25:10328–10339. https://doi.org/10.1007/s11356-017-9177-0
Thomas SJ, Yoon I-K (2019) A review of Dengvaxia®: development to deployment. Hum Vaccin Immunother 15:1–20. https://doi.org/10.1080/21645515.2019.1658503
Undurraga EA, Halasa YA, Shepard DS (2016) Economic analysis of genetically modified mosquito strategies. Elsevier Inc.
Veerakumar K, Govindarajan M, Hoti SL (2014) Evaluation of plant-mediated synthesized silver nanoparticles against vector mosquitoes. Parasitol Res 113:4567–4577. https://doi.org/10.1007/s00436-014-4147-7
Velayutham K, Ramanibai R, Umadevi M (2016) Green synthesis of silver nanoparticles using Manihot esculenta leaves against Aedes aegypti and Culex quinquefasciatus. J Basic Appl Zool 74:37–40. https://doi.org/10.1016/j.jobaz.2016.06.002
Velu K, Elumalai D, Hemalatha P, Janaki A, Babu M, Hemavathi M, Kaleena PK (2015) Evaluation of silver nanoparticles toxicity of Arachis hypogaea peel extracts and its larvicidal activity against malaria and dengue vectors. Environ Sci Pollut Res 22:17769–17779. https://doi.org/10.1007/s11356-015-4919-3
Vijayaraghavan K, Ashokkumar T (2017) Plant-mediated biosynthesis of metallic nanoparticles: a review of literature, factors affecting synthesis, characterization techniques and applications. J Environ Chem Eng 5:4866–4883. https://doi.org/10.1016/j.jece.2017.09.026
Vimala RTV, Sathishkumar G, Sivaramakrishnan S (2015) Optimization of reaction conditions to fabricate nano-silver using Couroupita guianensis Aubl. (leaf & fruit) and its enhanced larvicidal effect. Spectrochim Acta A Mol Biomol Spectrosc 135:110–115. https://doi.org/10.1016/j.saa.2014.06.009
Weeratunga P, Rodrigo C, Fernando SD (2017) Rajapakse S (2017) Control methods for Aedes albopictus and Aedes aegypti. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD012759
WHO (2005) Guidelines for laboratory and field testing of mosquito larvicides, Geneve
WHO (2012) Global plan for insecticide resistance management in malaria vectors, Geneve
WHO (World Health Organization) (2016) Dengue control. In: https://www.who.int/denguecontrol/epidemiology/en/
Wilke ABB, Beier JC, Benelli G (2018) Transgenic mosquitoes – fact or fiction? Trends Parasitol 34:456–465. https://doi.org/10.1016/j.pt.2018.02.003
Yang S, Bai M, Yang J, Yuan Y, Zhang Y, Qin J, Kuang Y, Sampietro DA (2020) Chemical composition and larvicidal activity of essential oils from Peganum harmala, Nepeta cataria and Phellodendron amurense against Aedes aegypti (Diptera: Culicidae). Saudi Pharm J 28:560–564. https://doi.org/10.1016/j.jsps.2020.03.007
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We would like to thank CAPES by the doctorate fellowship conceived to the first author.
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On behalf of the co-authors of the manuscript entitled “Botanical insecticide–based nanosystems for the control of Aedes (Stegomyia) aegypti (L.) larvae”, I would like to inform that the overall contributions were as follows:
J.L.D. carried out the bibliographic search, summarized the papers, and wrote the initial draft of this review. A.E.M.F.M.O wrote and performed the revision of the manuscript M.C.P and M.L supervised the first author and performed the final revision and submission of the manuscript.
Yours sincerely,
Dr. Marlus Chorilli
Faculdade de Ciências Farmacêuticas—UNESPCampus Araraquara
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Duarte, J.L., Maciel de Faria Motta Oliveira, A., Pinto, M.C. et al. Botanical insecticide–based nanosystems for the control of Aedes (Stegomyia) aegypti larvae. Environ Sci Pollut Res 27, 28737–28748 (2020). https://doi.org/10.1007/s11356-020-09278-y
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DOI: https://doi.org/10.1007/s11356-020-09278-y