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Application of liquid chromatography-tandem mass spectrometry in quantitative bioanalyses of organic molecules in aquatic environment and organisms

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Abstract

Analytical methods using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) for the simultaneous determination of metabolites or contaminants (or both) in various tissues of aquatic organisms and in the aquatic environment have received increasing attention in the last few years. This review discusses the findings relevant to such procedures published between 2005 and 2015. The aim is to evaluate the advantages, restrictions, and performances of the procedures from sample preparation to mass spectrometry measurement. To support these discussions, a general knowledge on LC-MS/MS is also provided.

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    1. Department of Fisheries and Wildlife, Michigan State University, 480 Wilson Road, Room 13, Natural Resources Bldg., East Lansing, MI, 48824, USA

      Ugo Bussy, Ke Li & Weiming Li

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    Ugo Bussy and Ke Li contributed equally to this work.

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    Bussy, U., Li, K. & Li, W. Application of liquid chromatography-tandem mass spectrometry in quantitative bioanalyses of organic molecules in aquatic environment and organisms. Environ Sci Pollut Res 23, 9459–9479 (2016). https://doi.org/10.1007/s11356-016-6433-7

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