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Catalytic performance of CuO/MgO nanocomposite for the regioselective synthesis of triazoles and investigation of antimicrobial activity

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Abstract

In this research, CuO/MgO nanocomposite was synthesized and characterized as a new, efficient and recyclable nanocatalyst, and then its catalytic activity was investigated on the regioselective synthesis of 1,4-disubstituted-1,2,3-triazole derivatives. The nanocatalyst was characterized by various methods, including XRD, FE-SEM, EDS, BET and TGA. Various triazole derivatives were synthesized from the reaction between propargyl ethers or terminal alkynes with aryl halides or alkyl halides with very good efficiency. Moreover, CuO/MgO nanocomposite was tested against six standard strains of bacteria to determine its antimicrobial activity. The results indicated that CuO/MgO nanocomposite had different levels of inhibition against different bacteria.

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Acknowledgements

We are grateful to the Shahrekord University for the support of this research.

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This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors.

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Correspondence to Jalal Albadi.

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Hosseipour, D., Albadi, J., Samimi, H.A. et al. Catalytic performance of CuO/MgO nanocomposite for the regioselective synthesis of triazoles and investigation of antimicrobial activity. Res Chem Intermed 50, 2015–2030 (2024). https://doi.org/10.1007/s11164-024-05266-w

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