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Effect of Preparation Based on Trametes Pubescens Xylotroph Fungi on Lipid Peroxidation in the Blood of Experimental Animals under Conditions of Dark Stress

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Using the model of dark stress caused by animal maintenance at dimmed light we showed that Trametin (product obtained during liquid-phase culturing of Trametes pubescens xylotroph fungi) effectively prevented oxidative stress under conditions of light deprivation. The preparation increased the level of unsaturation of lipids, reduced the concentration of primary and end-products of LPO, and increases both the integral parameter of the antioxidant defense system (total antioxidant activity) and its components (activity of superoxide dismutase and reduced glutathione).

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Authors and Affiliations

  1. Research Center for Family Health and Human Reproduction, Irkutsk, Russia

    L. I. Kolesnikova, S. I. Kolesnikov, M. A. Darenskaya, L. A. Grebenkina, L. I. Korytov, O. V. Bugun & N. V. Koroleva

  2. A. A. Ezhevsky Irkutsk State Agrarian University, Irkutsk, Russia

    E. D. Romanova & V. A. Chkhenkeli

  3. Irkutsk State University, Irkutsk, Russia

    I. N. Gutnik

  4. Russian X-Radiology Research Center, the Ministry of Health of the Russian Federation, Moscow, Russia

    F. F. Antonenko

Authors
  1. L. I. Kolesnikova
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  2. S. I. Kolesnikov
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  3. E. D. Romanova
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  4. V. A. Chkhenkeli
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  5. M. A. Darenskaya
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  6. L. A. Grebenkina
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  7. L. I. Korytov
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  8. O. V. Bugun
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  9. N. V. Koroleva
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  10. I. N. Gutnik
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  11. F. F. Antonenko
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Corresponding author

Correspondence to M. A. Darenskaya.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 12, pp. 730-733, December, 2016

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Kolesnikova, L.I., Kolesnikov, S.I., Romanova, E.D. et al. Effect of Preparation Based on Trametes Pubescens Xylotroph Fungi on Lipid Peroxidation in the Blood of Experimental Animals under Conditions of Dark Stress. Bull Exp Biol Med 162, 762–764 (2017). https://doi.org/10.1007/s10517-017-3707-0

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  • DOI: https://doi.org/10.1007/s10517-017-3707-0

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