We studied the state of the LPO–antioxidant defense system in men aged from 46 to 55 years. The main group included patients with obstructive sleep breathing disorders. The state of the antioxidant defense system was assessed by measuring the blood levels of LPO substrates with conjugated double bonds, conjugated dienes, ketodienes and conjugated trienes, MDA, retinol, α-tocopherol, reduced and oxidized glutathione, SOD activity, and the level of total antioxidant activity of blood. Calculation of antioxidant potential helps to identify the processes of “oxidative stress” in the main group, which is a pathogenetic substantiation for including antioxidant drugs in the complex therapy of patients with OSBD.
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References
A. M. Veyn, T. S. Yeligulashvili, and M. G. Poluektov, Sleep Apnea Syndrome [in Russian], Мoscow (2002).
V. B. Gavrilov, A. R. Gavrilova, and L. M. Mazhul’, Vopr. Med. Khimii, No, 1, 118-122 (1987).
V. B. Gavrilov and M. I. Mishkorudnaya, Lab. Delo, No. 3, 33-36 (1983).
G. I. Klebanov, I. V. Babenkova, Yu. O. Teselkin, et al., Ibid., No. 5, 59-62 (1988).
I. M. Madaeva, L. I. Kolesnikova, V. A. Petrova, et al., Patol. Fiziol. i Eksper. Ter., No. 3,.24-27 (2009).
E. B. Menshchikova, N. K. Zenkov, V. Z. Lankin, et al., Oxidative Stress. Pathological States and Diseases [in Russian], Novosibirsk (2008).
Patent No. 2194984. Way of Estimating Anti-and Pro-Oxidant Status of the Body by Determining Antioxidant Potential / A. S. Losev, V. I. Petrov, and A. F. Fesyuk, Published 16.10.2000.
Yu. V. Smolyaninova, L. I. Kolesnikova, I. M. Madaeva, et al., Byul. VSNTS SO RAMN, No. 1, 239-240 (2007).
I. E. Chazova and A. Yu. Litvin, Sistemnyye Gipertenzii, No. 2, 15-21 (2009).
R. Ch. Chernyauskene, Z. Z. Varshkyavichene, and P. S. Gribauskas, Lab. Delo, No.6, 362-365 (1984).
P. J. Hissin and R. Hilf, Anal. Biochem., 74, No. 1, 214-226 (1976).
H. P. Misra and I. Fridovich, J. Biol. Chem., 247, No. 10, 3170-3175 (1972).
A. Rechtschaffen and A. Kales, Manual of Standardized Terminology, Tecniques, and Criteria for the Scoring of Stages of Sleep and Wakefulness of Human Subjects, NIH publication No 204, Washington (1968).
J. W. Shepard, Principles and Practice of Sleep Medicine, 2nd ed., Philadelphia (1994), pp. 657-666.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 154, No. 12, pp. 695-697, December, 2012
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Kolesnikova, L.I., Madaeva, I.M., Semenova, N.V. et al. Antioxidant Potential of the Blood in Men with Obstructive Sleep Breathing Disorders. Bull Exp Biol Med 154, 731–733 (2013). https://doi.org/10.1007/s10517-013-2041-4
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DOI: https://doi.org/10.1007/s10517-013-2041-4