Skip to main content

Advertisement

SpringerLink
Log in

Effects of low-level laser therapy on bone regeneration of the midpalatal suture after rapid maxillary expansion

  • Original Article
  • Published:
Lasers in Medical Science Aims and scope Submit manuscript

Abstract

This study evaluated the effect of low-level laser therapy (LLLT) on bone regeneration at the midpalatal suture (MPS) after rapid maxillary expansion (RME), using cone beam computed tomography. Fourteen 8–14-year-old patients with transverse maxillary deficiency underwent RME with a Hyrax-type expander activated with one full turn after installation and two half turn daily activations until achieving overcorrection. Patients were randomly assigned to either a control group (RME alone, n = 4) or an experimental group (n = 10) in which RME was followed by 12 LLLT sessions (GaAlAs, p = 70 mW, λ = 780 nm, Ø = 0.04 cm2). Two tomographic images of the MPS were obtained—T0, after disjunction and T1, after 4 months. Bone regeneration was evaluated by measuring the optical density (OD) on the tomographic images using InVivo Dental 5.0 software. Data were analyzed by the paired Student’s t test (α = 0.05 %). A statistically significant difference between T0 and T1 OD values was observed in the laser-treated group (p = 0.00), but this difference was not significant in the control group (p = 0.20). Intergroup comparison of OD values at T1 revealed higher OD in the laser-treated group (p = 0.05). In conclusion, LLLT had a positive influence on bone regeneration of the midpalatal suture by accelerating the repair process.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Haas AJ (1961) Rapid expansion of the maxillary dental arch and nasal cavity by opening the midpalatal suture. Angle Orthod 31:73–90

    Google Scholar 

  2. Silva Filho OG, Montes LAP, Torelly LF (1995) Rapid maxillary expansion in the deciduous and mixed dentition evaluated through posteroanterior cephalometric analysis. Am J Orthod Dentofac Orthop 107:268–275

    Article  Google Scholar 

  3. Sato FRL, Mannarino S, Asprino L, Moraes M (2014) Prevalence and treatment of dentofacial deformities on a multiethnic population: a retrospective study. Oral Maxillofac Surg 18:173–179

    PubMed  Google Scholar 

  4. Weissheimer A, Menezes LM, Mezomo M, Dias DM, Lima EMS, Rizzatto CSMD (2011) Immediate effects of rapid maxillary expansion with Haas-type and hyrax-type expanders: a randomized clinical trial. Am J Orthod Dentofac Orthop 140:366–376

    Article  Google Scholar 

  5. Gurgel JA, Malmstrom MFV, Pizan-Vercelino CRM (2012) Ossification of the midpalatal suture after surgically assisted rapid maxillary expansion. Eur J Orthod 34:39–43

    Article  Google Scholar 

  6. Skidmore KJ, Brook KJ, Thomson WM, Harding WJ (2006) Factors influencing treatment time in orthodontic patients. Am J Orthod Dentofac Orthop 129:230–238

    Article  Google Scholar 

  7. Cepera F, Torres FC, Scanavini MA, Paranhos LR, Capeloza LF, Cardoso MA et al (2012) Effect of a low-level laser on bone regeneration after rapid maxillary expansion. Am J Orthod Dentofac Orthop 141:444–450

    Article  Google Scholar 

  8. Santiago VCCE, Piram A, Fuziy A (2012) Effect of soft laser in bone repair after expansion of the midpalatal suture in dogs. Am J Orthod Dentofac Orthop 142:615–624

    Article  Google Scholar 

  9. Saito S, Shimizu N (1997) Stimulatory effects of low-power laser irradiation on bone regeneration in midpalatal suture during expansion in the rat. Am J Orthod Dentofac Orthop 111:525–532

    Article  CAS  Google Scholar 

  10. Rosa CB, Habib FAL, Araújo TS, Aragão JS, Gomes RS, Barbosa AFS et al (2014) Effect of the laser and light-emitting diode (LED) phototherapy on midpalatal suture bone formation after rapid maxilla expansion: a Raman spectroscopy analysis. Lasers Med Sci 29:859–867

    Article  PubMed  Google Scholar 

  11. Kanzaki H, Chiba M, Arai K, Takahashi I, Haruyama N, Nishimura M et al (2006) Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement. Gene Ther 13:678–685

    Article  CAS  PubMed  Google Scholar 

  12. Kim YD, Kim SS, Kim TG, Kim GC, Park SB, Son WS (2007) Effect of low level laser treatment during tooth movement-immunohistochemical study of RANKL, RANK, OPG: an experimental study in rats. Laser Phys Lett 4:616–623

    Article  CAS  Google Scholar 

  13. Fujita S, Yamaguchi M, Utsunomiya T, Yamamoto H, Kasai K (2008) Low-energy laser stimulates tooth movement velocity via expression of RANK and RANKL. Orthod Craniofacial Res 11:143–155

    Article  CAS  Google Scholar 

  14. Abreu MR, Viegas VN, Pagnoncelli RM, Lima EMS, Farret AM, Kulcznski FZ et al (2010) Infrared laser therapy after surgically assisted rapid palatal expansion to diminish pain and accelerate bone healing. World J Orthod 11:273–277

    PubMed  Google Scholar 

  15. Angeletti P, Pereira MD, Gomes HC, Hino CT, Ferreira LM (2010) Effect of low-level laser therapy (GaAlAs) on bone regeneration in midpalatal anterior suture after surgically assisted rapid maxillary expansion. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:38–46

    Article  Google Scholar 

  16. Petrick S, Hothan T, Hietschold V (2011) Bone density of the midpalatal suture 7 months after surgically assisted rapid palatal expansion in adults. Am J Orthod Dentofac Orthop 139:109–116

    Article  Google Scholar 

  17. Parenti SI, Checchi L, Fini M, Tschon M (2014) Different doses of low-level laser irradiation modulate the in vitro response of osteoblast-like cells. J Biomed Opt 19:108002

    Article  Google Scholar 

  18. Sannomiya EK, Macedo MMC, Siqueira DF, Goldenberg FC, Bommarito S (2007) Evaluation of optical density of the midpalatal suture 3 months after surgically assisted rapid maxillary expansion. Dentomaxillofac Radiol 36:97–101

    Article  CAS  PubMed  Google Scholar 

  19. Lione R, Ballanti F, Franchi L, Baccetti T, Cozza P (2008) Treatment and posttreatment skeletal effects of rapid maxillary expansion studied with low-dose computed tomography in growing subjects. Am J Orthod Dentofac Orthop 134:389–392

    Article  Google Scholar 

  20. Pereira MD, Prado GPR, Abramoff MMF, Aloise AC, Ferreira LM (2010) Classification of midpalatal suture opening after surgically assisted rapid maxillary expansion using computed tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110:41–45

    Article  PubMed  Google Scholar 

  21. Ahrari F, Madani AS, Ghafouri ZS, Tunér J (2014) The efficacy of low-level laser therapy for the treatment of myogenous temporomandibular joint disorder. Lasers Med Sci 29:551–557

    Article  PubMed  Google Scholar 

  22. Ferrante M, Petrini M, Trentini P, Perfetti G, Spoto G (2013) Effect of low-level laser therapy after extraction of impacted lower third molars. Lasers Med Sci 28:845–849

    Article  PubMed  Google Scholar 

  23. Obradovic R, Kesie L, Mihailovic D, Antic S, Jovanovic G, Petrovic A et al (2013) A histological evaluation of a low-level laser therapy as an adjunct to periodontal therapy in patients with diabetes mellitus. Lasers Med Sci 28:19–24

    Article  PubMed  Google Scholar 

  24. Machado MAAM, Sakai VT, Silva TC, Tessarolli V, Carvalho FP, Moretti ABS et al (2010) Therapeutic laser in surgical procedures of pediatric dentistry: case reports. J Oral Laser Appl 10:175–180

    Google Scholar 

  25. Cruz DR, Kohara EK, Ribeiro MS, Wetter NV (2004) Effects of low-intensity laser therapy on the orthodontic movement velocity of human teeth: a preliminary study. Lasers Surg Med 35:117–120

    Article  PubMed  Google Scholar 

  26. Camacho AD, Paredes AC, Aldana RL (2008) An in vitro study of the reaction of periodontal and gingival fibroblasts to low-level laser irradiation: a pilot study. J Oral Laser Appl 6:235–244

    Google Scholar 

  27. Abi-Ramia LBP, Stuani AS, Stuani MBS, Mendes AM (2010) Effects of low-level laser therapy and orthodontic tooth movement on dental pulps in rats. Angle Orthod 80:116–122

    Article  PubMed  Google Scholar 

  28. Yamaguchi M, Hayashi M, Fujita S, Yoshida T, Utsunomiya T, Yamamoto H et al (2010) Low-energy laser irradiation facilitates the velocity of tooth movement and the expressions of matrix metalloproteinase-9, cathepsin K, and alpha(v) beta(3) integrin in rats. Eur J Orthod 32:131–139

    Article  PubMed  Google Scholar 

  29. Silva APRB, Petri AD, Crippa GE, Stuani AS, Stuani AS, Rosa AL et al (2012) Effect of low-level laser therapy after rapid maxillary expansion on proliferation and differentiation of osteoblastic cells. Lasers Med Sci 27:777–783

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Dental Clinics, School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Rua Alexandre Baraúna, 949 - Rodolfo Teófilo, Fortaleza, CE, CEP: 60430160, Brazil

    Fabíola Nogueira Holanda Ferreira, Juliana Oliveira Gondim, José Jeová Siebra Moreira Neto, Pedro Cesar Fernandes dos Santos, Lúcio Mitsuo Kurita & Maria Walderez Andrade de Araújo

  2. Department of Restorative Dentistry, School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, CE, Brazil

    Karina Matthes de Freitas Pontes

Authors
  1. Fabíola Nogueira Holanda Ferreira
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Juliana Oliveira Gondim
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. José Jeová Siebra Moreira Neto
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Pedro Cesar Fernandes dos Santos
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Karina Matthes de Freitas Pontes
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Lúcio Mitsuo Kurita
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Maria Walderez Andrade de Araújo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Fabíola Nogueira Holanda Ferreira.

Ethics declarations

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This research received approval from the institutional ethics committee of the Federal University of Ceará (protocol #58/12).

Conflict of interest

The authors deny any conflicts of interest.

Informed consent

The study purposes were fully explained to the parents/guardians, who signed a written informed consent form authorizing children’s enrolment in the study. Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ferreira, F.N.H., Gondim, J.O., Neto, J.J.S.M. et al. Effects of low-level laser therapy on bone regeneration of the midpalatal suture after rapid maxillary expansion. Lasers Med Sci 31, 907–913 (2016). https://doi.org/10.1007/s10103-016-1933-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10103-016-1933-8

Keywords

Search

Navigation