Skip to main content

Advertisement

Log in

Manipulation under anesthesia as a therapy option for postoperative knee stiffness: a retrospective matched-pair analysis

  • Knee Arthroplasty
  • Published:
Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Introduction

Due to demographic changes, total knee arthroplasty (TKA) is one of the most frequently performed orthopedic surgeries. Therapies for associated postoperative complications, such as postoperative knee stiffness (PKS), are becoming increasingly important. The aim of this retrospective matched-pair analysis was to evaluate mid-term-results following manipulation under anesthesia (MUA).

Materials and methods

Fifty-one patients with PKS were evaluated and 51 matched-pair patients without PKS after primary TKA were chosen for the control group. In addition to the range of motion, the functionality was recorded by Knee Society Score (KSS), Western Ontario and Mc Masters Universities Osteoarthritis Index (WOMAC), and Short-Form-12 Questionnaire (SF-12). Experience of pain was mapped using a 10-point Numeric Rating Scale (NRS), and the analgesic requirement was mapped using the WHO step scheme. A final follow-up examination was conducted approximately three years after TKA. To evaluate potential risk factors for the development of PKS, TKA alignment was measured via postoperative X-ray images.

Results

Improvement of the average knee flexion of 35.7° and total flexion of 107.4° was detected in PKS patients after MUA. The flexion of the control group was 112.4°; no significant between-group difference was present regarding prosthesis type, sex, age and BMI. Regarding KSS, WOMAC, and SF-12, the MUA cohort achieved statistically-relevant lower overall scores than the control group, p = 0.006, p = 0.005, p = 0.001, respectively. Significantly higher experiences of pain and a higher need for analgesics in MUA patients were reported (p = 0.001 and p < 0.001, respectively). Radiological evaluation of the prosthesis alignment did not show any differences between the two groups.

Conclusions

MUA can improve mobility after PKS, whereby MUA seemed to be a functional therapy option for PKS. Compared to the control group, the MUA group showed lower functional values and an increased experience of pain. A correlation between prosthesis malalignment and MUA could not be detected radiologically. Further studies are necessary to investigate the reasons for PKS.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Jenkins PJ, Clement ND, Hamilton DF, Gaston P, Patton JT, Howie CR (2013) Predicting the cost-effectiveness of total hip and knee replacement: a health economic analysis. Bone Jt J 95(1):115–121

    Article  Google Scholar 

  2. Jacobs CA, Christensen CP (2014) Factors influencing patient satisfaction two to five years after primary total knee arthroplasty. J Arthroplasty 29(6):1189–1191

    Article  PubMed  Google Scholar 

  3. Bozic KJ, Kurtz SM, Lau E, Ong K, Chiu V, Vail TP (2010) The epidemiology of revision total knee arthroplasty in the United States. Clin Orthop Relat Res 468(1):45–51

    Article  PubMed  Google Scholar 

  4. March LM, Cross MJ, Lapsley H, Brnabic AJ, Tribe KL, Bachmeier CJ (1999) Outcomes after hip or knee replacement surgery for osteoarthritis. A prospective cohort study comparing patients’ quality of life before and after surgery with age-related population norms. Med J Aust 171(5):235–238

    Article  CAS  PubMed  Google Scholar 

  5. Jones CA, Voaklander DC, Johnston DW, Suarez-Almazor ME (2000) Health related quality of life outcomes after total hip and knee arthroplasties in a community based population. J Rheumatol 27(7):1745–1752

    CAS  PubMed  Google Scholar 

  6. Shields RK, Enloe LJ, Leo KC (1999) Health related quality of life in patients with total hip or knee replacement. Arch Phys Med Rehabil 80(5):572–579

    Article  CAS  PubMed  Google Scholar 

  7. Brander VA, Stulberg SD, Adams AD, Harden RN, Bruehl S, Stanos SP (2003) Predicting total knee replacement pain: a prospective, observational study. Clin Orthop Relat Res 416:27–36

    Article  Google Scholar 

  8. Du H, Tang H, Gu JM, Zhou YX (2014) Patient satisfaction after posterior-stabilized total knee arthroplasty: a functional specific analysis. Knee 21(4):866–870

    Article  PubMed  Google Scholar 

  9. Quintana JM, Escobar A, Arostegui I, Bilbao A, Azkarate J, Goenaga JI (2006) Health-related quality of life and appropriateness of knee or hip joint replacement. Arch Intern Med 166(2):220–226

    Article  PubMed  Google Scholar 

  10. Bawa HS, Wera GD, Kraay MJ, Marcus RE, Goldberg VM (2013) Predictors of range of motion in patients undergoing manipulation after TKA. Clin Orthop Relat Res 471(1):258–263

    Article  PubMed  Google Scholar 

  11. Issa K, Kapadia BH, Kester M, Khanuja HS, Delanois RE, Mont MA (2014) Clinical, objective, and functional outcomes of manipulation under anesthesia to treat knee stiffness following total knee arthroplasty. J Arthroplasty 29(3):548–552

    Article  PubMed  Google Scholar 

  12. Keating EM, Ritter MA, Harty LD, Haas G, Meding JB, Faris PM (2007) Manipulation after total knee arthroplasty. J Bone Jt Surg Am 89(2):282–286

    Article  Google Scholar 

  13. Rubinstein RA Jr, DeHaan A (2010) The incidence and results of manipulation after primary total knee arthroplasty. Knee 17(1):29–32

    Article  PubMed  Google Scholar 

  14. Ipach I, Mittag F, Lahrmann J, Kunze B, Kluba T (2011) Arthrofibrosis after TKA—influence factors on the absolute flexion and gain in flexion after manipulation under anaesthesia. BMC Musculoskelet Disord 12(12):184

    Article  PubMed  PubMed Central  Google Scholar 

  15. Yeoh D, Nicolaou N, Goddard R, Willmott H, Miles K, East D (2012) Manipulation under anaesthesia post total knee replacement: long term follow up. Knee 19(4):329–331

    Article  PubMed  Google Scholar 

  16. Kim SH, Gaiser S, Meehan JP (2012) Epidemiology of primary hip and knee arthroplasties in Germany: 2004 to 2008. J Arthroplasty 27(10):1777–1782

    Article  PubMed  Google Scholar 

  17. Ghani H, Maffulli N, Khanduja V (2012) Management of stiffness following total knee arthroplasty: a systematic review. Knee 19(6):751–759

    Article  CAS  PubMed  Google Scholar 

  18. Yercan HS, Sugun TS, Bussiere C, Ait Si Selmi T, Davies A, Neyret P (2006) Stiffness after total knee arthroplasty: prevalence, management and outcomes. Knee 13(2):111–117

    Article  PubMed  Google Scholar 

  19. Calliess T, Ettinger M, Hulsmann N, Ostermeier S, Windhagen H (2015) Update on the etiology of revision TKA—evident trends in a retrospective survey of 1449 cases. Knee 22(3):174–179

    Article  PubMed  Google Scholar 

  20. Ayers DC, Franklin PD, Ploutz-Snyder R, Boisvert CB (2005) Total knee replacement outcome and coexisting physical and emotional illness. Clin Orthop Relat Res 440:157–161

    Article  PubMed  Google Scholar 

  21. Gadinsky NE, Ehrhardt JK, Urband C, Westrich GH (2011) Effect of body mass index on range of motion and manipulation after total knee arthroplasty. J Arthroplasty 26(8):1194–1197

    Article  PubMed  Google Scholar 

  22. Pfefferle KJ, Shemory ST, Dilisio MF, Fening SD, Gradisar IM (2014) Risk factors for manipulation after total knee arthroplasty: a pooled electronic health record database study. J Arthroplasty 29(10):2036–2038

    Article  PubMed  Google Scholar 

  23. Gandhi R, de Beer J, Leone J, Petruccelli D, Winemaker M, Adili A (2006) Predictive risk factors for stiff knees in total knee arthroplasty. J Arthroplasty 21(1):46–52

    Article  PubMed  Google Scholar 

  24. Mohammed R, Syed S, Ahmed N (2009) Manipulation under anaesthesia for stiffness following knee arthroplasty. Ann R Coll Surg Engl 91(3):220–223

    Article  PubMed  PubMed Central  Google Scholar 

  25. Ritter MA, Harty LD, Davis KE, Meding JB, Berend ME (2003) Predicting range of motion after total knee arthroplasty. Clustering, log-linear regression, and regression tree analysis. J Bone Jt Surg Am 85(7):1278–1285

    Article  Google Scholar 

  26. Kim J, Nelson CL, Lotke PA (2004) Stiffness after total knee arthroplasty. Prevalence of the complication and outcomes of revision. J Bone Jt Surg Am 86(7):1479–1484

    Article  Google Scholar 

  27. Boldt JG, Stiehl JB, Hodler J, Zanetti M, Munzinger U (2006) Femoral component rotation and arthrofibrosis following mobile-bearing total knee arthroplasty. Int Orthop 30(5):420–425

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  28. Bellemans J, Robijns F, Duerinckx J, Banks S, Vandenneucker H (2005) The influence of tibial slope on maximal flexion after total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 13(3):193–196

    Article  CAS  PubMed  Google Scholar 

  29. Harvie P, Larkin J, Scaddan M, Longstaff LM, Sloan K, Beaver RJ (2013) Stiffness after total knee arthroplasty: does component alignment differ in knees requiring manipulation? A retrospective cohort study of 281 patients. J Arthroplasty 28(1):14–19

    Article  PubMed  Google Scholar 

  30. Laskin RS, Beksac B (2004) Stiffness after total knee arthroplasty. J Arthroplasty 19(4 Suppl 1):41–46

    Article  PubMed  Google Scholar 

  31. Shoji H, Solomonow M, Yoshino S, D'Ambrosia R, Dabezies E (1990) Factors affecting postoperative flexion in total knee arthroplasty. Orthopedics 13(6):643–649

    CAS  PubMed  Google Scholar 

  32. Peters CL, Shirley B, Erickson J (2006) The effect of a new multimodal perioperative anesthetic regimen on postoperative pain, side effects, rehabilitation, and length of hospital stay after total joint arthroplasty. J Arthroplasty 21(6 Suppl 2):132–138

    Article  PubMed  Google Scholar 

  33. Evans KN, Lewandowski L, Pickett A, Strauss JE, Gordon WT (2013) Outcomes of manipulation under anesthesia versus surgical management of combat-related arthrofibrosis of the knee. J Surg Orthop Adv 22(1):36–41

    Article  PubMed  Google Scholar 

  34. Ipach I, Schafer R, Lahrmann J, Kluba T (2011) Stiffness after knee arthrotomy: evaluation of prevalence and results after manipulation under anaesthesia. Orthop Traumatol Surg Res 97(3):292–296

    Article  CAS  PubMed  Google Scholar 

  35. Scranton PE Jr (2001) Management of knee pain and stiffness after total knee arthroplasty. J Arthroplasty 16(4):428–435

    Article  PubMed  Google Scholar 

  36. Fox JL, Poss R (1981) The role of manipulation following total knee replacement. J Bone Jt Surg Am 63(3):357–362

    Article  CAS  Google Scholar 

  37. Namba RS, Inacio M (2007) Early and late manipulation improve flexion after total knee arthroplasty. J Arthroplasty 22(6 Suppl 2):58–61

    Article  PubMed  Google Scholar 

  38. Esler CN, Lock K, Harper WM, Gregg PJ (1999) Manipulation of total knee replacements. Is the flexion gained retained? J Bone Jt Surg Br 81(1):27–29

    Article  CAS  Google Scholar 

  39. Bullinger M, Kirchberger I (1998) SF-36 Fragebogen zum Gesundheitszustand. Hogrefe-Verlag GmbH & Co. KG, Göttingen

    Google Scholar 

  40. Meneghini RM, Pierson JL, Bagsby D, Ziemba-Davis M, Berend ME, Ritter MA (2007) Is there a functional benefit to obtaining high flexion after total knee arthroplasty? J Arthroplasty 22(6 Suppl 2):43–46

    Article  PubMed  Google Scholar 

  41. Desai AS, Karmegam A, Dramis A, Board TN, Raut V (2014) Manipulation for stiffness following total knee arthroplasty: when and how often to do it? Eur J Orthop Surg Traumatol 24(7):1291–1295

    Article  PubMed  Google Scholar 

  42. Schiavone Panni A, Cerciello S, Vasso M, Tartarone M (2009) Stiffness in total knee arthroplasty. J Orthop Traumatol 10(3):111–118

    Article  PubMed  PubMed Central  Google Scholar 

  43. Issa K, Banerjee S, Kester MA, Khanuja HS, Delanois RE, Mont MA (2014) The effect of timing of manipulation under anesthesia to improve range of motion and functional outcomes following total knee arthroplasty. J Bone Jt Surg Am 96(16):1349–1357

    Article  Google Scholar 

  44. Lavernia CJ, Villa JM, Iacobelli DA (2015) What is the role of mental health in primary total knee arthroplasty? Clin Orthop Relat Res 473(1):159–163

    Article  PubMed  Google Scholar 

  45. Cheuy VA, Foran JRH, Paxton RJ, Bade MJ, Zeni JA, Stevens-Lapsley JE (2017) Arthrofibrosis associated with total knee arthroplasty. J Arthroplasty 32(8):2604–2611

    Article  PubMed  Google Scholar 

  46. Mayr HO, Fassbender FF, Prall WC, Haasters F, Bernstein A, Stoehr A (2019) Immunohistochemical examination in arthrofibrosis of the knee joint. Arch Orthop Trauma Surg 139(3):383–391

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daiwei Yao.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yao, D., Bruns, F., Ettinger, S. et al. Manipulation under anesthesia as a therapy option for postoperative knee stiffness: a retrospective matched-pair analysis. Arch Orthop Trauma Surg 140, 785–791 (2020). https://doi.org/10.1007/s00402-020-03381-y

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00402-020-03381-y

Keywords

Navigation