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Potential therapeutic effects of crocin

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Abstract

Crocin, a natural bioactive compound derived from saffron (Crocus sativus) and other Crocus genera, has gained significant attention recently due to its potential therapeutic properties. The multifaceted nature of crocin’s biological effects has piqued the interest of researchers and health enthusiasts, prompting further investigations into its mechanisms of action and therapeutic applications. This review article comprehensively explores the emerging evidence supporting crocin’s role as a promising ally in protecting against metabolic disorders. The review covers the molecular mechanisms underlying crocin’s beneficial effects and highlights its potential applications in preventing and treating diverse pathological conditions. Understanding the mechanisms through which crocin exerts its protective effects could advance scientific knowledge and offer potential avenues for developing novel therapeutic interventions. As we uncover the potential of crocin as a valuable ally in the fight against disorders, it becomes evident that nature’s palette holds remarkable solutions for enhancing our health.

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Acknowledgements

The authors wish to thank the Deputy for Research and Technology of the Islamic Azad University of Tabriz for support of the study. We would like to thank the Clinical Research Development Unit of Tabriz Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, Iran for their assistance in this research.

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  1. Department of Sport Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran

    Laleh Pourmousavi, Rasoul Hashemkandi Asadi, Farzad Zehsaz & Roghayeh Pouzesh Jadidi

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  1. Laleh Pourmousavi
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  2. Rasoul Hashemkandi Asadi
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  3. Farzad Zehsaz
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  4. Roghayeh Pouzesh Jadidi
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The authors have equally contributed to the conceptualization, data curation, original draft preparation, and editing work. The authors confirm that no paper mill and artificial intelligence were used.

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Correspondence to Rasoul Hashemkandi Asadi.

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Pourmousavi, L., Asadi, R.H., Zehsaz, F. et al. Potential therapeutic effects of crocin. Naunyn-Schmiedeberg's Arch Pharmacol (2024). https://doi.org/10.1007/s00210-024-03131-6

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