Summary
J. B. S. Haldane has recently developed a theory for experiments in which induced autosomal recessive lethals in the monse are detected through their linkage with single marker genes in several different chromosomes. A theory is now given for experiments using several marker genes in one chromosome; linkage group V is taken as an example. It is concluded that the two methods may not differ greatly in their efficiency.
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References
Carter, T. C. (1954).Z. indukt. Abstamm.-u. Vererhlehre,86, 210–23.
Carter, T. C., Lyon, M. F. &Phillips, R. J. S. (1955).J. Genet. 53, 154–66.
Carter, T. C., Lyon, M. F. &Phillips, R. J. S. (1956).J. Genet. 54, 462–73.
Carter, T. C. &Robertson, A. (1952).Proc. Boy. Soc. B,139, 410–26.
Falconee, D. S. &Snell, G. D. (1962).J. Hered. 43, 53–7.
Grüneberg, H. (1935).J. Genet. 31, 157–62.
Grüneberg, H. (1936).J. Genet. 33, 255–65.
Haldane, J. B. S. (1919).J. Genet. 8, 299–309.
Haldane, J. B. S. (1956).J. Genet. 54, 327–42.
Mallyon, S. (1951).Nature, Lond.,168, 113–9.
Slizynski, B. M. (1949).J. Genet. 49, 242–5.
Slizynski, B. M. (1955).J. Genet. 53, 597–605.
Slizynski, B. M. (1956).Heredity,10, 283.
Snell, G. D. (1935).Genetics,20, 545–67.
Snell, G. D. (1946).Genetics,31, 157–80.
Snell, G. D. &Dickie, M. M. (1954).Heredity,8, 271–3.
Wallis.W. A. (1947). InTechniques of Statistical Analysis (editors C. Eisenhart, M. W. Hastay and W. A. Wallis); New York: McGraw-Hill Book Company, Inc.
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Carter, T.C. The use of linked masker genes for detecting recessive autosomal lethals in the mouse. J Genet 55, 585–595 (1957). https://doi.org/10.1007/BF02984074
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DOI: https://doi.org/10.1007/BF02984074